PMID- 35040740
OWN - NLM
STAT- MEDLINE
DCOM- 20230911
LR  - 20230911
IS  - 1549-7852 (Electronic)
IS  - 1040-8398 (Linking)
VI  - 63
IP  - 23
DP  - 2023
TI  - Application of starch-based nanoparticles and cyclodextrin for prebiotics 
      delivery and controlled glucose release in the human gut: a review.
PG  - 6126-6137
LID - 10.1080/10408398.2022.2028127 [doi]
AB  - Starches are a major constituent of staple foods and are the main source of 
      energy in the human diet (55-70%). In the gastrointestinal tract, starches are 
      hydrolyzed into glucose by alpha-amylase and alpha-glucosidase, which leads to a 
      postprandial glucose elevation. High levels of blood glucose levels over 
      sustained periods may promote type 2 diabetes mellitus (T2DM) and obesity. 
      Increasing consumption of starchy foods with a lower glycemic index may therefore 
      contribute to improved health. In this paper, the preparation and properties of 
      several starch-based nanoparticles (SNPs) and cyclodextrins (CDs) derivatives are 
      reviewed. In particular, we focus on the various mechanisms responsible for the 
      ability of these edible nanomaterials to modulate glucose release and the gut 
      microbiome in the gastrointestinal tract. The probiotic functions are achieved 
      through encapsulation and protection of prebiotics or bioactive components in 
      foods or the human gut. This review therefore provides valuable information that 
      could be used to design functional foods for improving human health and 
      wellbeing.
FAU - Liu, Yuwan
AU  - Liu Y
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
FAU - Qiu, Chao
AU  - Qiu C
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
FAU - Li, Xiaojing
AU  - Li X
AD  - College of Light Industry and Food Engineering, Nanjing Forestry University, 
      Jiangsu, China.
FAU - McClements, David Julian
AU  - McClements DJ
AD  - Department of Food Science, University of Massachusetts, Amherst, MA, USA.
FAU - Wang, Chenxi
AU  - Wang C
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
FAU - Zhang, Zhiheng
AU  - Zhang Z
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
FAU - Jiao, Aiquan
AU  - Jiao A
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
FAU - Long, Jie
AU  - Long J
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
FAU - Zhu, Kunfu
AU  - Zhu K
AD  - Shandong Zhushi Pharmaceutical Group Co., LTD, Heze, China.
FAU - Wang, Jinpeng
AU  - Wang J
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
AD  - Beijing Advanced Innovation Center for Food Nutrition and Human Health, 
      China-Canada Joint Lab of Food Nutrition and Health (Beijing), School of Food and 
      Health, Beijing Technology and Business University (BTBU), Beijing, China.
FAU - Jin, Zhengyu
AU  - Jin Z
AUID- ORCID: 0000-0002-7802-9722
AD  - State Key Laboratory of Food Science and Technology, School of Food Science and 
      Technology, Synergetic Innovation Center of Food Safety and Nutrition, Jiangnan 
      University, Wuxi, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220118
PL  - United States
TA  - Crit Rev Food Sci Nutr
JT  - Critical reviews in food science and nutrition
JID - 8914818
RN  - IY9XDZ35W2 (Glucose)
RN  - 0 (Prebiotics)
RN  - 9005-25-8 (Starch)
RN  - 0 (Cyclodextrins)
RN  - 0 (Blood Glucose)
SB  - IM
MH  - Humans
MH  - Glucose
MH  - Prebiotics
MH  - Starch
MH  - *Diabetes Mellitus, Type 2
MH  - *Cyclodextrins
MH  - *Nanoparticles
MH  - Blood Glucose
OTO - NOTNLM
OT  - Nanoparticles
OT  - blood glucose control
OT  - delivery
OT  - diabetes
OT  - probiotic function
EDAT- 2022/01/19 06:00
MHDA- 2023/09/11 06:42
CRDT- 2022/01/18 12:22
PHST- 2023/09/11 06:42 [medline]
PHST- 2022/01/19 06:00 [pubmed]
PHST- 2022/01/18 12:22 [entrez]
AID - 10.1080/10408398.2022.2028127 [doi]
PST - ppublish
SO  - Crit Rev Food Sci Nutr. 2023;63(23):6126-6137. doi: 
      10.1080/10408398.2022.2028127. Epub 2022 Jan 18.