PMID- 35047229
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220430
IS  - 2151-4585 (Print)
IS  - 2151-4593 (Electronic)
IS  - 2151-4585 (Linking)
VI  - 13
DP  - 2022
TI  - Association of Acute Perioperative Myocardial Injury With All-Cause Mortality 
      Within 90 Days After Hip Fracture Repair in the Elderly: A Prospective Study.
PG  - 21514593211070129
LID - 10.1177/21514593211070129 [doi]
LID - 21514593211070129
AB  - INTRODUCTION: It remains unclear whether acute perioperative myocardial injury 
      (APMI) increases mortality in the elderly. This study aimed to investigate APMI's 
      association with mortality within 90 days after hip fracture repair in elderly 
      patients. MATERIALS AND METHODS: This prospective study enrolled elderly patients 
      admitted to the department of Traumatology and Orthopaedics in XXX Hospital, who 
      underwent surgery in 2018-2019 with a 90-day follow-up. According to survival 
      status within 90 days, survival and death groups were constituted. Clinical, 
      demographic, and laboratory indicators and 90-day mortality post-surgery were 
      recorded. APMI's association with 90-day mortality post-surgery was analyzed by 
      logistic regression. RESULTS: Totally 248 participants were enrolled, including 
      224 and 24 in the survival and death groups, respectively, for a mortality rate 
      of 9.7%. Compared with surviving individuals, the death group was older [81 
      (75-86) vs 87 (82-89) years], and had higher incidence rates of APMI (24.6% vs 
      58.3%), intertrochanteric fractures (41.1% vs 62.5%), preoperative atrial 
      fibrillation (8.9% vs 29.2%), and dementia (73.7% vs 95.8%) (all P<.05). They 
      also showed higher pre-injury frail scale scores [1 (0-2) vs 3 (1-4)] and 
      Nottingham hip fracture scores (NHFSs) [4 (4-5) vs 6.5 (5-7)], lower Glomerular 
      filtration [62 (46.1-78.6) vs 44.37 (35-61.92) ml/min], and reduced odds of 
      glomerular filtration rate <60 mL/min (75.0% vs 46.9%) (all P < .05). APMI (OR = 
      3.294, 95% CI: 1.217-8.913) and NHFS (OR = 2.089, 95% CI: 1.353-3.225) 
      independently predicted 90-day mortality post-surgery (all P<.05). CONCLUSIONS: 
      APMI is associated with increased mortality risk within 90 days after hip 
      fracture repair in elderly patients.
CI  - (c) The Author(s) 2022.
FAU - Wang, Lei
AU  - Wang L
AD  - Department of Geratology, Beijing Jishuitan Hospital, Beijing, China. RINGGOLD: 
      66526
FAU - Cai, Meng
AU  - Cai M
AD  - Department of Geratology, Beijing Jishuitan Hospital, Beijing, China. RINGGOLD: 
      66526
FAU - Li, Xiaoying
AU  - Li X
AD  - Department of Geratology, Beijing Jishuitan Hospital, Beijing, China. RINGGOLD: 
      66526
FAU - Deng, Xiaohui
AU  - Deng X
AD  - Department of Geratology, Beijing Jishuitan Hospital, Beijing, China. RINGGOLD: 
      66526
FAU - Xue, Qiang
AU  - Xue Q
AD  - Department of Geratology, Beijing Jishuitan Hospital, Beijing, China. RINGGOLD: 
      66526
FAU - Zhou, Li
AU  - Zhou L
AD  - Department of Geratology, Beijing Jishuitan Hospital, Beijing, China. RINGGOLD: 
      66526
FAU - Yang, Minghui
AU  - Yang M
AUID- ORCID: 0000-0003-1244-4242
AD  - Department of Orthopaedics and Traumatology, Beijing Jishuitan Hospital, Beijing, 
      China. RINGGOLD: 66526
LA  - eng
PT  - Journal Article
DEP - 20220112
PL  - United States
TA  - Geriatr Orthop Surg Rehabil
JT  - Geriatric orthopaedic surgery & rehabilitation
JID - 101558150
PMC - PMC8761883
OTO - NOTNLM
OT  - 90-day all-cause mortality
OT  - acute perioperative myocardial injury
OT  - elderly population
OT  - hip fracture
OT  - myocardial injury and mortality
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2022/01/21 06:00
MHDA- 2022/01/21 06:01
PMCR- 2022/01/12
CRDT- 2022/01/20 06:04
PHST- 2022/01/20 06:04 [entrez]
PHST- 2022/01/21 06:00 [pubmed]
PHST- 2022/01/21 06:01 [medline]
PHST- 2022/01/12 00:00 [pmc-release]
AID - 10.1177_21514593211070129 [pii]
AID - 10.1177/21514593211070129 [doi]
PST - epublish
SO  - Geriatr Orthop Surg Rehabil. 2022 Jan 12;13:21514593211070129. doi: 
      10.1177/21514593211070129. eCollection 2022.