PMID- 35049024
OWN - NLM
STAT- MEDLINE
DCOM- 20220407
LR  - 20220407
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 26
IP  - 1
DP  - 2022 Jan
TI  - A systematic review and meta-analysis on the efficacy of probiotics for bacterial 
      vaginosis.
PG  - 90-98
LID - 27752 [pii]
LID - 10.26355/eurrev_202201_27752 [doi]
AB  - OBJECTIVE: The current study aimed at assessing the overall efficacy of 
      probiotics for the treatment of bacterial vaginosis (BV) through the review of 
      relevant studies. MATERIALS AND METHODS: A systematic literature review was 
      conducted based largely on the following electronic databases updated to May 
      2021: Embase, the Cochrane Library, and PubMed, with the use of keywords. The 
      investigators also thoroughly reviewed key pertinent sources in the literature 
      for further inclusion. RESULTS: Eighteen studies including 1651 patients were 
      selected in the present meta-analysis. In comparison with antibiotics, 
      antibiotics plus probiotics significantly decreased the recurrence rate of BV (at 
      1-3 months and overall analysis) and increased the cure/remission rate of BV (at 
      1-3 months and overall analysis). Compared with placebo, probiotics decreased the 
      recurrence rate of BV (at 1-3 months and overall analysis) and increased the 
      cure/remission rate of BV (at 1-3 months). Compared with antibiotics, probiotics 
      significantly decreased the recurrence rate of BV (at <1 month, 1-3 months and 
      overall analysis) as well as the incidence of adverse events (AEs) (at less than 
      1 month) and increased the cure/remission rate of BV (at 1-3 months). 
      CONCLUSIONS: In comparison with short-term probiotics treatment (<1 month), 
      long-term probiotics treatment (1-3 months) yields superior beneficial outcomes 
      and efficacy in the treatment of BV.
FAU - Liu, H-F
AU  - Liu HF
AD  - Department of Gynecology, Beijing Ditan Hospital, Capital Medical University, 
      Beijing, China. yinuo_76@126.com.
FAU - Yi, N
AU  - Yi N
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Systematic Review
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Administration, Intravaginal
MH  - Anti-Bacterial Agents/therapeutic use
MH  - Female
MH  - Humans
MH  - *Probiotics/therapeutic use
MH  - *Vaginosis, Bacterial/drug therapy
EDAT- 2022/01/21 06:00
MHDA- 2022/04/08 06:00
CRDT- 2022/01/20 09:07
PHST- 2022/01/20 09:07 [entrez]
PHST- 2022/01/21 06:00 [pubmed]
PHST- 2022/04/08 06:00 [medline]
AID - 27752 [pii]
AID - 10.26355/eurrev_202201_27752 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2022 Jan;26(1):90-98. doi: 
      10.26355/eurrev_202201_27752.