PMID- 35049421
OWN - NLM
STAT- MEDLINE
DCOM- 20230210
LR  - 20230307
IS  - 1502-7732 (Electronic)
IS  - 0300-9742 (Linking)
VI  - 52
IP  - 2
DP  - 2023 Mar
TI  - Complications after minor salivary gland biopsy: a retrospective study of 630 
      patients from two Swedish centres.
PG  - 208-216
LID - 10.1080/03009742.2021.1999671 [doi]
AB  - OBJECTIVES: The aims of the study were to investigate the prevalence of impaired 
      sensation after minor salivary gland biopsy (MSGB) in two Swedish centres 
      [Karolinska University Hospital (KUH) and Skane University Hospital (SUH)] and to 
      assess its impact on quality of life (QoL) and associated risk factors. METHOD: A 
      questionnaire including questions regarding the presence of impaired sensation, 
      impact on QoL, and impact on everyday life was sent to patients who had undergone 
      MSGB between 2007 and 2016, and their medical notes were scrutinized. RESULTS: 
      The study included 630 patients (505 from KUH and 125 from SUH). In KUH the 
      biopsies were performed by rheumatologists and in SUH by dentists or oral and 
      maxillofacial surgeons (OMSs). Long-standing, probably permanent, impaired 
      sensation after MSGB was reported by 21% of patients, and was associated with 
      lower age and absence of anti-SSA antibodies. Patients with long-standing 
      impaired sensation reported the inconvenience (1-10) of impaired sensation as 4.0 
      (2.0-7.0) [median (interquartile range)], and 32% reported an influence on their 
      QoL, the reported influence (1-10) on everyday life being 3.0 (1.0-5.0). When 
      comparing the outcomes from KUH and SUH, patients from SUH reported a 
      significantly lower frequency of long-standing impaired sensation (14% vs 23%; p 
      = 0.02). CONCLUSION: A high frequency of long-standing impaired sensation after 
      MSGB was found among patients who had undergone MSGB, although it had a low 
      impact on everyday life. The complication frequency was less pronounced when a 
      dentist or an OMS had performed the biopsy.
FAU - Olsson, P
AU  - Olsson P
AUID- ORCID: 0000-0001-7318-833X
AD  - Department of Clinical Sciences, Malmo, Rheumatology, Lund University, Malmo, 
      Sweden.
AD  - Section of Rheumatology, Department of Medicine, Helsingborg Central Hospital, 
      Sweden.
FAU - Ekblad, F
AU  - Ekblad F
AD  - Department of Clinical Sciences, Malmo, Rheumatology, Lund University, Malmo, 
      Sweden.
FAU - Hassler, A
AU  - Hassler A
AD  - Department of Clinical Sciences, Malmo, Rheumatology, Lund University, Malmo, 
      Sweden.
FAU - Bengtsson, M
AU  - Bengtsson M
AUID- ORCID: 0000-0003-0838-5737
AD  - Department of Clinical Sciences, Faculty of Medicine, Lund University, Lund, 
      Sweden.
AD  - Department of Oral & Maxillofacial Surgery, Skane University Hospital, Lund, 
      Sweden.
FAU - Warfvinge, G
AU  - Warfvinge G
AUID- ORCID: 0000-0002-0682-3871
AD  - Department of Oral Biology and Pathology, Faculty of Odontology, Malmo 
      University, Malmo, Sweden.
FAU - Mandl, T
AU  - Mandl T
AUID- ORCID: 0000-0002-7143-7088
AD  - Department of Clinical Sciences, Malmo, Rheumatology, Lund University, Malmo, 
      Sweden.
FAU - Kvarnstrom, M
AU  - Kvarnstrom M
AUID- ORCID: 0000-0002-4948-8380
AD  - Rheumatology Unit, Department of Medicine, Karolinska University Hospital, 
      Karolinska Institutet, Stockholm, Sweden.
AD  - Academic Specialist Center, Center for Rheumatology, Stockholm Health Services 
      Region, Stockholm, Sweden.
LA  - eng
PT  - Journal Article
DEP - 20220120
PL  - England
TA  - Scand J Rheumatol
JT  - Scandinavian journal of rheumatology
JID - 0321213
RN  - 89022-11-7 (2'-carbomethoxyphenyl 4-guanidinobenzoate)
SB  - IM
MH  - Humans
MH  - *Salivary Glands, Minor/pathology
MH  - *Sjogren's Syndrome/pathology
MH  - Retrospective Studies
MH  - Quality of Life
MH  - Sweden/epidemiology
MH  - Hypesthesia/pathology
MH  - Biopsy/adverse effects
EDAT- 2022/01/21 06:00
MHDA- 2023/02/11 06:00
CRDT- 2022/01/20 12:21
PHST- 2022/01/21 06:00 [pubmed]
PHST- 2023/02/11 06:00 [medline]
PHST- 2022/01/20 12:21 [entrez]
AID - 10.1080/03009742.2021.1999671 [doi]
PST - ppublish
SO  - Scand J Rheumatol. 2023 Mar;52(2):208-216. doi: 10.1080/03009742.2021.1999671. 
      Epub 2022 Jan 20.