PMID- 35056978
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220128
IS  - 1999-4923 (Print)
IS  - 1999-4923 (Electronic)
IS  - 1999-4923 (Linking)
VI  - 14
IP  - 1
DP  - 2021 Dec 29
TI  - Rowan Berries: A Potential Source for Green Synthesis of Extremely Monodisperse 
      Gold and Silver Nanoparticles and Their Antimicrobial Property.
LID - 10.3390/pharmaceutics14010082 [doi]
LID - 82
AB  - Rowanberries (Sorbus aucuparia) are omnipresent in Europe. The medicinal 
      importance of rowanberries is widely known and corresponds to the active 
      ingredients present in the fruits, mainly polyphenols, carotenoids, and organic 
      acids. In the current study, we explored rowanberries for the reduction of gold 
      and silver salts into nanoparticles. Rowanberries-mediated gold nanoparticles 
      (RB-AuNPs) formed within 5 s at room temperature, and silver nanoparticles 
      (RB-AgNPs) formed in 20 min at 90  degrees C. The produced nanoparticles were thoroughly 
      characterized by UV-Vis spectroscopy, scanning electron microscopy (SEM), energy 
      dispersive X-ray (EDX), transmission electron microscopy (TEM), dynamic light 
      scattering (DLS), single-particle inductively coupled plasma-mass spectrometry 
      (sp-ICP-MS), thermogravimetric analysis (TGA), Fourier transform-infrared 
      spectroscopy (FT-IR) and matrix-assisted laser desorption/ionization time of 
      flight mass spectrometry (MALDI-TOF). The characterization confirmed that the 
      nanoparticles are highly monodisperse, spherical, stable over long periods, and 
      exhibit a high negative zeta potential values. The produced RB-AuNPs and RB-AgNPs 
      were 90-100 nm and 20-30 nm in size with a thick biological corona layer 
      surrounding them, providing extreme stability but lowering the antimicrobial 
      activity. The antimicrobials study of RB-AgNPs revealed that the nanoparticles 
      have antimicrobial potential with an MBC value of 100 microg/mL against P. aeruginosa 
      and 200 microg/mL against E. coli.
FAU - Singh, Priyanka
AU  - Singh P
AUID- ORCID: 0000-0001-7654-5339
AD  - The Novo Nordisk Foundation, Center for Biosustainability, Technical University 
      of Denmark, DK-2800 Kogens Lyngby, Denmark.
FAU - Mijakovic, Ivan
AU  - Mijakovic I
AD  - The Novo Nordisk Foundation, Center for Biosustainability, Technical University 
      of Denmark, DK-2800 Kogens Lyngby, Denmark.
AD  - Systems and Synthetic Biology Division, Department of Biology and Biological 
      Engineering, Chalmers University of Technology, SE-412 96 Gothenburg, Sweden.
LA  - eng
PT  - Journal Article
DEP - 20211229
PL  - Switzerland
TA  - Pharmaceutics
JT  - Pharmaceutics
JID - 101534003
PMC - PMC8781835
OTO - NOTNLM
OT  - Sorbus aucuparia
OT  - antimicrobial activity
OT  - gold nanoparticles
OT  - monodisperse
OT  - rowanberries
OT  - silver nanoparticles
OT  - stable
COIS- The authors declare that the submitted work was not carried out in the presence 
      of any personal, professional, or financial relationships that could potentially 
      be construed as a conflict of interest.
EDAT- 2022/01/22 06:00
MHDA- 2022/01/22 06:01
PMCR- 2021/12/29
CRDT- 2022/01/21 01:16
PHST- 2021/12/07 00:00 [received]
PHST- 2021/12/17 00:00 [revised]
PHST- 2021/12/24 00:00 [accepted]
PHST- 2022/01/21 01:16 [entrez]
PHST- 2022/01/22 06:00 [pubmed]
PHST- 2022/01/22 06:01 [medline]
PHST- 2021/12/29 00:00 [pmc-release]
AID - pharmaceutics14010082 [pii]
AID - pharmaceutics-14-00082 [pii]
AID - 10.3390/pharmaceutics14010082 [doi]
PST - epublish
SO  - Pharmaceutics. 2021 Dec 29;14(1):82. doi: 10.3390/pharmaceutics14010082.