PMID- 35058131
OWN - NLM
STAT- MEDLINE
DCOM- 20220328
LR  - 20220401
IS  - 1878-7533 (Electronic)
IS  - 1550-7289 (Linking)
VI  - 18
IP  - 3
DP  - 2022 Mar
TI  - Parallel improvement of systolic function with surgical weight loss in patients 
      with heart failure and reduced ejection fraction: a systematic review and 
      patient-level meta-analysis.
PG  - 433-438
LID - S1550-7289(21)00596-7 [pii]
LID - 10.1016/j.soard.2021.12.016 [doi]
AB  - BACKGROUND: Morbid obesity (MO) is an increasingly common condition in patients 
      with heart failure with reduced ejection fraction (HFrEF). Although substantial 
      weight loss in morbidly obese patients has proved to slow the progression of 
      heart failure, parallel alteration of ejection fraction (EF) and New York Heart 
      Association (NYHA) functional class along with post-bariatric surgery weight loss 
      is yet to be determined. OBJECTIVES: This systematic review aimed to measure the 
      effect of bariatric weight loss on EF and NYHA functional class in patients with 
      HFrEF. METHODS: A systematic literature review was performed in Medline/PubMed to 
      identify studies in patients with MO and pre-existing HFrEF, who underwent 
      bariatric surgery. RESULTS: A total of 11 studies encompassing 136 patients with 
      HFrEF undergoing bariatric surgery for MO were included. Six studies provided 
      patient-level data on 37 cases. Patients lost an average body mass index (BMI) of 
      12.9 +/- 4.2 kg/m(2) (5.1 to 23 kg/m(2)) after an average follow up of 22.43 +/- 18.6 
      months (2-89 mo). There was a direct correlation between BMI loss and EF 
      improvement (r = 0.61, P < .0001), but not between BMI loss and NYHA functional 
      class changes (r = 0.17, P = .4). CONCLUSION: Weight loss induced by bariatric 
      surgery results in parallel EF increase in patients with MO and HFrEF. However, 
      current data does not indicate a parallel improvement of clinical symptoms (NYHA 
      functional class) along with such an increase in EF in this population of 
      patients.
CI  - Copyright (c) 2021 American Society for Bariatric Surgery. Published by Elsevier 
      Inc. All rights reserved.
FAU - Shoar, Saeed
AU  - Shoar S
AD  - Department of Clinical Research, ScientificWriting Corp, Houston, Texas. 
      Electronic address: saeedshoar@scientificwriting.org.
FAU - Manzoor, Asifa
AU  - Manzoor A
AD  - Akhtar Saeed Medical and Dental College, Lahore, Pakistan.
FAU - Abdelrazek, Ahmad Saeed
AU  - Abdelrazek AS
AD  - School of Medicine, October 6 University School of Medicine, Giza, Egypt.
FAU - Ikram, Waleed
AU  - Ikram W
AD  - Division of Hematology and Oncology, Department of Medicine, Mayo Clinic, 
      Phoenix, Arizona.
FAU - Hosseini, Fatemeh
AU  - Hosseini F
AD  - School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.
FAU - Shoar, Nasrin
AU  - Shoar N
AD  - Department of Clinical Research, ScientificWriting Corp, Houston, Texas; School 
      of Medicine, Kashan University of Medical Sciences, Kashan, Iran.
FAU - Khavandi, Soheila
AU  - Khavandi S
AD  - Division of Cardiology, Department of Medicine, Tabriz University of Medical 
      Sciences, Tabriz, Iran.
FAU - Shah, Ahmed Ali
AU  - Shah AA
AD  - School of Medicine, Quaid-e-Azam Medical College, Bahawalpur, Pakistan.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20211217
PL  - United States
TA  - Surg Obes Relat Dis
JT  - Surgery for obesity and related diseases : official journal of the American 
      Society for Bariatric Surgery
JID - 101233161
SB  - IM
MH  - *Bariatric Surgery
MH  - Body Mass Index
MH  - Gastrectomy/methods
MH  - *Gastric Bypass/methods
MH  - *Heart Failure/complications/surgery
MH  - Humans
MH  - *Obesity, Morbid/complications/surgery
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - Treatment Outcome
MH  - Weight Loss
OTO - NOTNLM
OT  - Bariatric surgery
OT  - EF
OT  - Ejection fraction
OT  - HFrEF
OT  - Heart failure with reduced ejection fraction
OT  - Morbid obesity
OT  - NYHA
OT  - New York Heart Association
OT  - Roux-en-Y gastric bypass
OT  - Sleeve Gastrectomy
EDAT- 2022/01/22 06:00
MHDA- 2022/03/29 06:00
CRDT- 2022/01/21 05:56
PHST- 2021/09/03 00:00 [received]
PHST- 2021/11/18 00:00 [revised]
PHST- 2021/12/11 00:00 [accepted]
PHST- 2022/01/22 06:00 [pubmed]
PHST- 2022/03/29 06:00 [medline]
PHST- 2022/01/21 05:56 [entrez]
AID - S1550-7289(21)00596-7 [pii]
AID - 10.1016/j.soard.2021.12.016 [doi]
PST - ppublish
SO  - Surg Obes Relat Dis. 2022 Mar;18(3):433-438. doi: 10.1016/j.soard.2021.12.016. 
      Epub 2021 Dec 17.