PMID- 35067618
OWN - NLM
STAT- MEDLINE
DCOM- 20220812
LR  - 20230928
IS  - 1549-8425 (Electronic)
IS  - 1549-8417 (Print)
IS  - 1549-8417 (Linking)
VI  - 18
IP  - 5
DP  - 2022 Aug 1
TI  - Postdischarge Adverse Events Among Neonates Admitted to the Neonatal Intensive 
      Care Unit.
PG  - 462-469
LID - 10.1097/PTS.0000000000000960 [doi]
AB  - OBJECTIVES: We aimed to determine the rate of postdischarge adverse events (AEs), 
      classify the types of postdischarge AEs, and identify risk factors for 
      postdischarge AEs among neonates admitted to the neonatal intensive care unit 
      (NICU). STUDY DESIGN: This was a prospective cohort study of neonates admitted to 
      the NICU from February 2017 through June 2019. We enrolled 170 neonates from a 
      level 4 NICU who were being discharged home and whose parents can speak English 
      and could be contacted after discharge. The main outcome of the study was 
      postdischarge AEs based on structured telephone interviews, health record review, 
      and adjudication by 2 blinded, trained physicians using a previously established 
      methodology. RESULTS: Fourteen percent of 170 neonates admitted to the NICU 
      experienced postdischarge AEs, with 48% being either preventable or ameliorable. 
      Adverse drug events and procedural complications comprised most of the AEs (48%), 
      but most of the preventable and ameliorable AEs were due to management, 
      therapeutic, or diagnostic errors. Seventy-nine percent of neonates who suffered 
      an AE experienced either a readmission to the hospital or an emergency department 
      visit. Neonates admitted to a level 4 NICU from another NICU (level 1, 2, or 3) 
      (adjusted odds ratio, 3.62; 95% confidence interval, 1.27-12.60; P = 0.01) and 
      those 28 to 36 weeks (adjusted odds ratio, 11.38; 95% confidence interval, 
      1.67-127.98; P = 0.01) had a significantly higher risk of AEs at discharge. 
      CONCLUSIONS: Neonates discharged from a level 4 NICU were at high risk for 
      experiencing postdischarge AEs. The identification of AE types and risk factors 
      can be used to guide efforts to develop interventions to improve neonatal patient 
      safety during the postdischarge period.
CI  - Copyright (c) 2022 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Tsilimingras, Dennis
AU  - Tsilimingras D
AD  - From the Department of Family Medicine & Public Health Sciences, Wayne State 
      University School of Medicine, Detroit.
FAU - Natarajan, Girija
AU  - Natarajan G
FAU - Bajaj, Monika
AU  - Bajaj M
FAU - Agarwal, Prashant
AU  - Agarwal P
AD  - Neonatology, Children's Hospital of Michigan.
FAU - Lua, Jorge
AU  - Lua J
FAU - Deriemacker, Amanda
AU  - Deriemacker A
AD  - Wayne State University College of Nursing, Detroit, Michigan.
FAU - Zuair, Areeg
AU  - Zuair A
AD  - Taibah University College of Nursing, Kingdom of Saudi Arabia.
FAU - Misra, Dawn
AU  - Misra D
AD  - Department of Epidemiology and Biostatistics, Michigan State University College 
      of Human Medicine, East Lansing, Michigan.
FAU - Janisse, James
AU  - Janisse J
AD  - From the Department of Family Medicine & Public Health Sciences, Wayne State 
      University School of Medicine, Detroit.
FAU - Zhang, Liying
AU  - Zhang L
AD  - From the Department of Family Medicine & Public Health Sciences, Wayne State 
      University School of Medicine, Detroit.
FAU - Schnipper, Jeffrey
AU  - Schnipper J
AD  - Division of General Medicine, Brigham and Women's Hospital and Harvard Medical 
      School, Boston, Massachusetts.
LA  - eng
GR  - R01 HD089000/HD/NICHD NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
DEP - 20220124
PL  - United States
TA  - J Patient Saf
JT  - Journal of patient safety
JID - 101233393
SB  - IM
MH  - Aftercare
MH  - Hospitalization
MH  - Humans
MH  - Infant, Newborn
MH  - *Intensive Care Units, Neonatal
MH  - *Patient Discharge
MH  - Prospective Studies
PMC - PMC9300771
MID - NIHMS1754541
COIS- The authors disclose no conflict of interest.
EDAT- 2022/01/25 06:00
MHDA- 2022/08/13 06:00
PMCR- 2023/08/01
CRDT- 2022/01/24 05:48
PHST- 2022/01/25 06:00 [pubmed]
PHST- 2022/08/13 06:00 [medline]
PHST- 2022/01/24 05:48 [entrez]
PHST- 2023/08/01 00:00 [pmc-release]
AID - 01209203-202208000-00014 [pii]
AID - 10.1097/PTS.0000000000000960 [doi]
PST - ppublish
SO  - J Patient Saf. 2022 Aug 1;18(5):462-469. doi: 10.1097/PTS.0000000000000960. Epub 
      2022 Jan 24.