PMID- 35067709 OWN - NLM STAT- MEDLINE DCOM- 20220317 LR - 20240317 IS - 1760-4788 (Electronic) IS - 1279-7707 (Linking) VI - 26 IP - 1 DP - 2022 TI - Association of Cognitive Performance with Frailty in Older Individuals with Cognitive Complaints. PG - 89-95 LID - 10.1007/s12603-021-1712-5 [doi] AB - OBJECTIVES: Frailty is a risk factor for poor cognitive performance in older adults. However, few studies have evaluated the association of cognitive performance with frailty in a low- to middle-income country (LMIC). This study aimed to investigate an association between cognitive performance and frailty in older adults with memory complaints in Brazil. Secondarily, we aim to assess an association of cognitive performance with gait speed and grip strength. DESIGN: Cross-sectional study. SETTING: Outpatient service from a LMIC. PARTICIPANTS: Older adults with memory complaints reported by the participants, their proxies, or their physicians. MEASUREMENTS: Frailty was evaluated using the Cardiovascular Health Study criteria. A neuropsychological battery evaluated memory, attention, language, visuospatial function, executive function. Linear regression analysis with adjustment for age, sex, and education was used. We also evaluated the interaction of education with frailty, grip strength, and gait speed. RESULTS: Prefrailty was associated with poor performance in the memory domain, as well as slower gait speed was associated with worse performance in memory, attention, language, and executive function. Frailty and grip strength were not associated with cognitive performance. Interactions of education with gait speed were significant for global performance, as well as for attention and visuospatial ability. CONCLUSION: In elderly patients with memory complaints, prefrailty was associated with poor memory performance. Slowness was associated with poorer performance in some cognitive domains, mainly in participants with low education. FAU - Lin, S M AU - Lin SM AD - Claudia K. Suemoto, Division of Geriatrics, University of Sao Paulo Medical School, Av. Doutor Arnaldo, 455, room 1353, Sao Paulo, Brazil., Phone number: +551130618725, E-mail: cksuemoto@usp.br. FAU - Apolinario, D AU - Apolinario D FAU - Vieira Gomes, G C AU - Vieira Gomes GC FAU - Cassales Tosi, F AU - Cassales Tosi F FAU - Magaldi, R M AU - Magaldi RM FAU - Busse, A L AU - Busse AL FAU - Gil, G AU - Gil G FAU - Ribeiro, E AU - Ribeiro E FAU - Satomi, E AU - Satomi E FAU - Aprahamian, I AU - Aprahamian I FAU - Filho, W J AU - Filho WJ FAU - Suemoto, C K AU - Suemoto CK LA - eng PT - Journal Article PL - France TA - J Nutr Health Aging JT - The journal of nutrition, health & aging JID - 100893366 SB - IM MH - Aged MH - Cognition MH - *Cognition Disorders MH - *Cognitive Dysfunction/psychology MH - Cross-Sectional Studies MH - Executive Function MH - Frail Elderly MH - *Frailty/complications MH - Humans OTO - NOTNLM OT - Frailty OT - cognitive impairment OT - dementia OT - older adults COIS- None to declare EDAT- 2022/01/25 06:00 MHDA- 2022/03/18 06:00 CRDT- 2022/01/24 05:49 PHST- 2022/01/24 05:49 [entrez] PHST- 2022/01/25 06:00 [pubmed] PHST- 2022/03/18 06:00 [medline] AID - S1279-7707(23)00907-7 [pii] AID - 10.1007/s12603-021-1712-5 [doi] PST - ppublish SO - J Nutr Health Aging. 2022;26(1):89-95. doi: 10.1007/s12603-021-1712-5.