PMID- 35069231
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220125
IS  - 1664-042X (Print)
IS  - 1664-042X (Electronic)
IS  - 1664-042X (Linking)
VI  - 12
DP  - 2021
TI  - The Systolic and Diastolic Cardiac Function of Patients With Type 2 Diabetes 
      Mellitus: An Evaluation of Left Ventricular Strain and Torsion Using Conventional 
      and Speckle Tracking Echocardiography.
PG  - 726719
LID - 10.3389/fphys.2021.726719 [doi]
LID - 726719
AB  - Objectives: This study aimed to quantify left ventricular (LV) myocardial strain 
      and torsion in patients with type 2 diabetes mellitus (T2DM) and evaluate their 
      systolic and diastolic function using conventional and speckle tracking 
      echocardiography. Methods: Forty-seven patients with T2DM were divided into a 
      group without microvascular complications (the DM A group) and a group with 
      microvascular complications (the DM B group), while another 27 healthy 
      participants acted as the control group. All the participants had had an 
      echocardiography examination. All the original data were imported into EchoPAC 
      workstation for the analysis and quantification of LV strain and torsion. 
      Results: Compared with the control group, the LV end-diastolic volume, 
      end-systolic volume, and ejection fraction of the DM A and DM B groups showed no 
      significant differences, but the global longitudinal strain and the global 
      circular strain were reduced in the DM B group. There were significant 
      differences in the left ventricular relative wall thickness (RWT), left 
      ventricular mass index (LVMI), the early mitral valvular blood flow velocity 
      peak/left ventricular sidewall mitral annulus late peak velocity, left 
      ventricular sidewall mitral annulus early peak velocity/left ventricular sidewall 
      mitral annulus late peak velocity, isovolumic relaxation time, peak twisting, 
      peak untwisting velocity (PUV), untwisting rate (UntwR), time peak twisting 
      velocity (TPTV), and time peak untwisting velocity (TPUV) between the DM A, DM B, 
      and control groups. While the peak twisting velocity (PTV) was slower in the DM B 
      group compared with the control group, the RWT, PTV, PUV, UntwR, TPTV, and TPUV 
      in the DM B group were significantly different from the DM A group. Conclusion: 
      The cardiac function of patients with T2DM in its early stages, when there are no 
      microvascular complications, could be monitored with the analysis of 
      two-dimensional strain and torsion.
CI  - Copyright (c) 2022 Yang, Fang, Chen, Lv and Kang.
FAU - Yang, Qing-Mei
AU  - Yang QM
AD  - Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical 
      Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, 
      Taiyuan, China.
AD  - Department of Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Fang, Jian-Xiu
AU  - Fang JX
AD  - Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical 
      Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, 
      Taiyuan, China.
AD  - Department of Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Chen, Xiao-Yan
AU  - Chen XY
AD  - Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical 
      Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, 
      Taiyuan, China.
AD  - Department of Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Lv, Hong
AU  - Lv H
AD  - Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical 
      Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, 
      Taiyuan, China.
AD  - Department of Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
FAU - Kang, Chun-Song
AU  - Kang CS
AD  - Department of Ultrasound, Shanxi Bethune Hospital, Shanxi Academy of Medical 
      Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, 
      Taiyuan, China.
AD  - Department of Ultrasound, Tongji Hospital, Tongji Medical College, Huazhong 
      University of Science and Technology, Wuhan, China.
LA  - eng
PT  - Journal Article
DEP - 20220107
PL  - Switzerland
TA  - Front Physiol
JT  - Frontiers in physiology
JID - 101549006
PMC - PMC8777120
OTO - NOTNLM
OT  - 2D-speckle tracking imaging
OT  - diabetes mellitus
OT  - diabetic cardiomyopathy
OT  - left ventricular
OT  - strain
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/01/25 06:00
MHDA- 2022/01/25 06:01
PMCR- 2022/01/07
CRDT- 2022/01/24 08:48
PHST- 2021/06/17 00:00 [received]
PHST- 2021/11/30 00:00 [accepted]
PHST- 2022/01/24 08:48 [entrez]
PHST- 2022/01/25 06:00 [pubmed]
PHST- 2022/01/25 06:01 [medline]
PHST- 2022/01/07 00:00 [pmc-release]
AID - 10.3389/fphys.2021.726719 [doi]
PST - epublish
SO  - Front Physiol. 2022 Jan 7;12:726719. doi: 10.3389/fphys.2021.726719. eCollection 
      2021.