PMID- 35085735 OWN - NLM STAT- MEDLINE DCOM- 20220505 LR - 20220505 IS - 1569-8041 (Electronic) IS - 0923-7534 (Linking) VI - 33 IP - 4 DP - 2022 Apr TI - Concomitant type 2 diabetes mellitus (T2DM) in metastatic melanoma patients could be related to lower level of LAG-3: a transcriptomic analysis of a retrospective cohort. PG - 445-447 LID - S0923-7534(22)00016-3 [pii] LID - 10.1016/j.annonc.2022.01.007 [doi] FAU - Mallardo, D AU - Mallardo D AD - Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione 'G. Pascale', Naples, Italy. FAU - Cortellini, A AU - Cortellini A AD - Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK. FAU - Capone, M AU - Capone M AD - Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione 'G. Pascale', Naples, Italy. FAU - Madonna, G AU - Madonna G AD - Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione 'G. Pascale', Naples, Italy. FAU - Pinato, D J AU - Pinato DJ AD - Department of Surgery & Cancer, Imperial College London, Hammersmith Hospital, Du Cane Road, W120HS London, UK; Division of Oncology, Department of Translational Medicine, University of Piemonte Orientale, Novara, Italy. FAU - Warren, S AU - Warren S AD - NanoString Technologies, Seattle, USA. FAU - Simeone, E AU - Simeone E AD - Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione 'G. Pascale', Naples, Italy. FAU - Ascierto, P A AU - Ascierto PA AD - Melanoma, Cancer Immunotherapy and Development Therapeutics Unit, Istituto Nazionale Tumori IRCCS Fondazione 'G. Pascale', Naples, Italy. Electronic address: paolo.ascierto@gmail.com. LA - eng PT - Letter DEP - 20220125 PL - England TA - Ann Oncol JT - Annals of oncology : official journal of the European Society for Medical Oncology JID - 9007735 SB - IM MH - Cohort Studies MH - *Diabetes Mellitus, Type 2/complications/genetics MH - Humans MH - *Melanoma/complications/genetics MH - Retrospective Studies MH - Transcriptome COIS- Disclosure AC received consulting fees from MSD, BMS, AstraZeneca, and Roche; and speakers' fee from AstraZeneca, MSD, Novartis, and Astellas. DJP received lecture fees from ViiV Healthcare, Bayer Healthcare, BMS, Roche, EISAI, and Falk Foundation; travel expenses from BMS and Bayer Healthcare; consulting fees for Mina Therapeutics, EISAI, Roche, DaVolterra, and Astra Zeneca; and research funding (to institution) from MSD and BMS. SW is employee and stockholder in NanoString Technologies. ES received honoraria from Bristol Myers Squibb, Novartis, and Merck Sharp & Dohme. PAA has/had a consultant/advisory role for Bristol Meyers Squibb, Roche-Genentech, Merck Sharp & Dohme, Novartis, Merck Serono, Pierre-Fabre, AstraZeneca, Sun Pharma, Sanofi, Idera, Sandoz, Immunocore, 4SC, Italfarmaco, Nektar, Boehringer-Ingelheim, Eisai, Regeneron, Daiichi Sankyo, Pfizer, OncoSec, Nouscom, Lunaphore, Seagen, and iTeos; received research funds from Bristol Meyers Squibb, Roche-Genentech, Pfizer, and Sanofi. All other authors have declared no conflicts of interest. EDAT- 2022/01/28 06:00 MHDA- 2022/05/06 06:00 CRDT- 2022/01/27 20:12 PHST- 2021/11/19 00:00 [received] PHST- 2022/01/11 00:00 [revised] PHST- 2022/01/11 00:00 [accepted] PHST- 2022/01/28 06:00 [pubmed] PHST- 2022/05/06 06:00 [medline] PHST- 2022/01/27 20:12 [entrez] AID - S0923-7534(22)00016-3 [pii] AID - 10.1016/j.annonc.2022.01.007 [doi] PST - ppublish SO - Ann Oncol. 2022 Apr;33(4):445-447. doi: 10.1016/j.annonc.2022.01.007. Epub 2022 Jan 25.