PMID- 35086071
OWN - NLM
STAT- MEDLINE
DCOM- 20220418
LR  - 20220418
IS  - 2057-1976 (Electronic)
IS  - 2057-1976 (Linking)
VI  - 8
IP  - 2
DP  - 2022 Feb 10
TI  - A dosimetric comparative analysis of Brainlab elements and Eclipse RapidArc for 
      spine SBRT treatment planning.
LID - 10.1088/2057-1976/ac4f97 [doi]
AB  - Purpose. This is a dosimetric study comparing stereotactic body radiotherapy 
      (SBRT) plans of spine tumors using Brainlab Elements Spine planning module 
      against Eclipse RapidArc plans. Dose conformity, dose gradient, dose fall-off, 
      and patient-specific quality assurance (QA) metrics were evaluated. 
      Methods:Twenty patients were immobilized in supine position using half Vac-Lok. A 
      prescription dose of 16 Gy in a single fraction was planned for Varian TrueBeam. 
      Conformal arc plans were generated with Pencil beam (PB), MonteCarlo (MC) in 
      Elements, and RapidArc with Acuros XB algorithm in Eclipse using identical 
      treatment geometry.Results. Eclipse, Elements PB, and Elements MC generated 
      dosimetrically conformal plans having Inverse Paddick Conformity Index (IPCI) 
      <1.3. All plans satisfied the dose constraints to target and OARs. Elements PB 
      had a sharper gradient than Elements MC with average GI of 3.67(95% CI: 
      3.52-3.82) and 4.06 (95% CI: 3.93-4.20) respectively. Eclipse plans were more 
      homogeneous with mean HI = 1.22 (95% CI: 1.20-1.23) that is lower than others. 
      Average maximum clinical target volume (CTV) doses were higher in Elements MC 
      with 22.31 Gy (95% CI: 21.87-22.74), while PB plans have 21.15 Gy (95% CI: 
      20.36-21.96), respectively. Elements MC and PB plans had lower average dose to 
      0.35 c.c. of spinal cord (D0.35cc) of 7.60 Gy (95% CI: 7.18-8.02) and 8.42 Gy 
      (95% CI: 7.83-9.01). All plans had >95% points passing the gamma QA criteria at 
      3%/2 mm.Conclusion. All treatment plans achieved clinically acceptable target 
      coverage >95% and meet spinal cord dose limits. Smart optimization in Brainlab 
      Elements spine module produced dosimetrically superior plans by better spinal 
      cord sparing.
CI  - (c) 2022 IOP Publishing Ltd.
FAU - Deshazer, Garron
AU  - Deshazer G
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
FAU - Narayanasamy, Ganesh
AU  - Narayanasamy G
AUID- ORCID: 0000-0002-7608-0612
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
FAU - Bimali, Milan
AU  - Bimali M
AD  - Department of Biostatistics, University of Arkansas for Medical Sciences, Little 
      Rock, AR, United States of America.
AD  - Winthrop P. Rockefeller Cancer Institute, University of Arkansas for Medical 
      Sciences, Little Rock, AR, United States of America.
FAU - Galhardo, Edvaldo
AU  - Galhardo E
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
AD  - Radiaion Oncology, Genesis Care, Bradenton, FL, United States of America.
FAU - Kalantari, Faraz
AU  - Kalantari F
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
FAU - Xia, Fen
AU  - Xia F
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
FAU - Penagaricano, Jose
AU  - Penagaricano J
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
AD  - H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, United States of 
      America.
FAU - Morrill, Steven
AU  - Morrill S
AD  - Department of Radiation Oncology, University of Arkansas for Medical Sciences, 
      Little Rock, AR, United States of America.
LA  - eng
PT  - Journal Article
DEP - 20220210
PL  - England
TA  - Biomed Phys Eng Express
JT  - Biomedical physics & engineering express
JID - 101675002
SB  - IM
MH  - Humans
MH  - Radiometry
MH  - *Radiosurgery/methods
MH  - Radiotherapy Dosage
MH  - Radiotherapy Planning, Computer-Assisted/methods
MH  - *Radiotherapy, Intensity-Modulated/methods
OTO - NOTNLM
OT  - brainlab spine
OT  - dose falloff
OT  - spine radiotherapy
OT  - spine sbrt
EDAT- 2022/01/28 06:00
MHDA- 2022/04/19 06:00
CRDT- 2022/01/27 20:18
PHST- 2021/12/21 00:00 [received]
PHST- 2022/01/27 00:00 [accepted]
PHST- 2022/01/28 06:00 [pubmed]
PHST- 2022/04/19 06:00 [medline]
PHST- 2022/01/27 20:18 [entrez]
AID - 10.1088/2057-1976/ac4f97 [doi]
PST - epublish
SO  - Biomed Phys Eng Express. 2022 Feb 10;8(2). doi: 10.1088/2057-1976/ac4f97.