PMID- 35094664
OWN - NLM
STAT- MEDLINE
DCOM- 20230315
LR  - 20240402
IS  - 1945-5119 (Electronic)
IS  - 1074-9357 (Print)
IS  - 1074-9357 (Linking)
VI  - 30
IP  - 3
DP  - 2023 Apr
TI  - The minimal clinically important difference of the motricity index score.
PG  - 298-303
LID - 10.1080/10749357.2022.2031532 [doi]
AB  - INTRODUCTION: The Motricity Index (MI) can predict motor function after 
      rehabilitation, but its minimal clinically important difference (MCID) has not 
      been established. The primary study aim was to estimate the MCID value of the MI 
      arm score. METHODS: Between 2017 and 2018, 173 participants hospitalized with 
      confirmed ischemic stroke were recruited into an observational rehabilitation 
      study. Participants with motor weakness as measured by the Fugl-Meyer 
      upper-extremity (FM-UE) and MI with complete baseline and follow-up assessments 
      at 3 months were included in this analysis. The longitudinal recovery of the MI 
      arm score was anchored to having a poor outcome based on the FM-UE recovery (<9) 
      longitudinally. Results reported include the area-under-curve (AUC), along with 
      sensitivity, specificity, and optimal cut-points based on maximizing the Youden 
      statistic. RESULTS: Sixty-nine patients (median [IQR] age 70 [18] years; 48% 
      male; 54% white) were included in the final analysis. Mean +/- standard deviation 
      outcome scores at 3-months were: MI arm: 83.19 +/- 22.80; FM-UE: 53.04 +/- 17.26. For 
      the primary results, the MI arm score optimal MCID cutoff for observed recovery 
      was 13 points with a sensitivity of 80% (95% Confidence Interval (CI)(67.6%, 
      92.4%)) and a specificity of 69.0% (95% CI (52.1, 85.8%)), and the AUC was 0.8082 
      (0.7007, 0.9157). CONCLUSIONS: This was the first study to report the MCID of the 
      MI arm score, as anchored to the FM-UE recovery between acute evaluation and 
      3-months. The estimated optimal MCID of improvement in the MI arm score was 13 
      points.
FAU - Lin, Chen
AU  - Lin C
AUID- ORCID: 0000-0001-5291-9674
AD  - Departments of Neurology, The University of Alabama at Birmingham, Birmingham, 
      AL, USA.
FAU - Arevalo, Yurany A
AU  - Arevalo YA
AD  - Departments of Neurology, The University of Alabama at Birmingham, Birmingham, 
      AL, USA.
FAU - Harvey, Richard L
AU  - Harvey RL
AD  - Department of Physical Medicine and Rehabilitation, Northwestern University, 
      Chicago, IL, USA.
FAU - Prabhakaran, Shyam
AU  - Prabhakaran S
AD  - Department of Neurology, The University of Chicago, Chicago, IL, USA.
FAU - Martin, Kimberly D
AU  - Martin KD
AD  - Departments of Epidemiology, The University of Alabama at Birmingham, Birmingham, 
      AL, USA.
LA  - eng
GR  - I21 RX003612/RX/RRD VA/United States
GR  - IK2 CX002104/CX/CSRD VA/United States
GR  - UL1 TR003096/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Research Support, U.S. Gov't, Non-P.H.S.
DEP - 20220130
PL  - England
TA  - Top Stroke Rehabil
JT  - Topics in stroke rehabilitation
JID - 9439750
SB  - IM
MH  - Humans
MH  - Male
MH  - Aged
MH  - Female
MH  - *Stroke Rehabilitation
MH  - *Stroke/complications/diagnosis
MH  - Minimal Clinically Important Difference
MH  - Recovery of Function
MH  - Disability Evaluation
MH  - Upper Extremity
PMC - PMC9338175
MID - NIHMS1776476
OTO - NOTNLM
OT  - Stroke rehabilitation
OT  - functional outcome measure
OT  - minimal clinically important difference
OT  - motricity index
OT  - stroke outcomes
OT  - upper limb
EDAT- 2022/02/01 06:00
MHDA- 2023/03/16 06:00
PMCR- 2024/04/01
CRDT- 2022/01/31 05:33
PHST- 2022/02/01 06:00 [pubmed]
PHST- 2023/03/16 06:00 [medline]
PHST- 2022/01/31 05:33 [entrez]
PHST- 2024/04/01 00:00 [pmc-release]
AID - 10.1080/10749357.2022.2031532 [doi]
PST - ppublish
SO  - Top Stroke Rehabil. 2023 Apr;30(3):298-303. doi: 10.1080/10749357.2022.2031532. 
      Epub 2022 Jan 30.