PMID- 35097180
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220430
IS  - 2352-5517 (Print)
IS  - 2352-5517 (Electronic)
IS  - 2352-5517 (Linking)
VI  - 29
DP  - 2022 Mar
TI  - Isolated case of platelet satellitism around white blood cells and phagocytosis 
      by neutrophils and monocytes.
PG  - e00264
LID - 10.1016/j.plabm.2022.e00264 [doi]
LID - e00264
AB  - INTRODUCTION: Rarely, platelets can interact with other blood elements, forming 
      platelet aggregates. This paper presents an isolated case of platelet satellitism 
      around neutrophils, lymphocytes and monocytes with platelet phagocytosis by both 
      neutrophils and monocytes. CASE PRESENTATION: The subject was an 89-year-old 
      woman with breast cancer on anti-estrogenic hormone cancer therapy. Whole blood 
      sample collected in a tube with EDTA (Ethylenediaminetetra-acetic acid) 
      anticoagulant was analysed within 4 hours, using an XN haematology analyser 
      (Sysmex). The CBC (complete blood count) presented the following results: WBC 
      (White blood cell) 4.0 x 10(9)/L, RBC (Red blood cell) 3.58 x 10(12)/L, 
      haemoglobin 116 g/L, haematocrit 34.9%, MCV (Mean corpuscular volume) 97.5 fL, 
      MCH (Mean corpuscular haemoglobin) 32.5 pg, MCHC (Mean corpuscular haemoglobin 
      concentration) 33.2 g ⁄dL, RDW (Red blood cell distribution width) 14.6% and PLT 
      (Platelet) 136. CONCLUSION: This manuscript describes the platelet satellitism 
      around neutrophils, lymphocytes and monocytes and the interesting, very rare and 
      singular phenomenon of platelet phagocytosis by not only neutrophils but also 
      monocytes.
CI  - (c) 2022 Published by Elsevier B.V.
FAU - Lorubbio, Maria
AU  - Lorubbio M
AD  - Chemical-Clinical Analysis Laboratory, San Donato Hospital, Via Pietro Nenni, 
      20/22, 52100, Arezzo, Italy.
FAU - Ognibene, Agostino
AU  - Ognibene A
AD  - Chemical-Clinical Analysis Laboratory, San Donato Hospital, Via Pietro Nenni, 
      20/22, 52100, Arezzo, Italy.
LA  - eng
PT  - Case Reports
DEP - 20220114
PL  - Netherlands
TA  - Pract Lab Med
JT  - Practical laboratory medicine
JID - 101690848
PMC - PMC8783087
OTO - NOTNLM
OT  - Isolated pseudothrombocytopenia
OT  - Microscopic evaluation
OT  - Platelet phagocytosis
OT  - Platelet satellitism
OT  - White blood cells
COIS- None.
EDAT- 2022/02/01 06:00
MHDA- 2022/02/01 06:01
PMCR- 2022/01/14
CRDT- 2022/01/31 06:01
PHST- 2021/07/26 00:00 [received]
PHST- 2022/01/12 00:00 [accepted]
PHST- 2022/01/31 06:01 [entrez]
PHST- 2022/02/01 06:00 [pubmed]
PHST- 2022/02/01 06:01 [medline]
PHST- 2022/01/14 00:00 [pmc-release]
AID - S2352-5517(22)00003-8 [pii]
AID - e00264 [pii]
AID - 10.1016/j.plabm.2022.e00264 [doi]
PST - epublish
SO  - Pract Lab Med. 2022 Jan 14;29:e00264. doi: 10.1016/j.plabm.2022.e00264. 
      eCollection 2022 Mar.