PMID- 35114503
OWN - NLM
STAT- MEDLINE
DCOM- 20220325
LR  - 20220325
IS  - 2468-7812 (Electronic)
IS  - 2468-7812 (Linking)
VI  - 58
DP  - 2022 Apr
TI  - Pressure pain threshold mappings of the infraspinatus muscle in chronic 
      unilateral shoulder pain patients do not reflect generalized hypersensitivity.
PG  - 102495
LID - S2468-7812(21)00179-X [pii]
LID - 10.1016/j.msksp.2021.102495 [doi]
AB  - OBJECTIVES: Increased mechanical sensitivity has been observed on the unaffected 
      side in chronic pain conditions, suggesting generalized or widespread 
      hypersensitivity. However, this cannot be considered as a universal response 
      since this hypersensitivity is inconsistent across muscle pain pathologies. The 
      aim of this study was to assess generalized hypersensitivity in chronic 
      unilateral shoulder pain, using pressure pain threshold (PPT) mappings of the 
      infraspinatus muscle. The proposed evaluation is based on the assessment of PPT 
      on a limited subset of sites, reducing potential habituation or sensitization 
      effects. METHODS: Twenty-nine patients with unilateral shoulder pain (USP) and 
      twenty-seven healthy volunteers were recruited. PPT was assessed using a manual 
      pressure algometer. Six sites distributed over the infraspinatus muscle were 
      assessed, and three repetitions were performed at each site. Mappings were 
      derived using two-dimensional interpolation. RESULTS: Lower PPT values were found 
      in the symptomatic side in comparison with the asymptomatic side at all 
      assessment sites (estimated difference: 1.42 +/- 0.10 kgf/cm(2), p < 0.001), but 
      there were no differences among the asymptomatic side of USP patients and any of 
      the sides in healthy volunteers (largest estimated difference: 0.17 +/- 0.28 
      kgf/cm(2), p = 0.927). Furthermore, the medial region of the infraspinatus muscle 
      showed higher mechanical sensitivity in both healthy volunteers and USP patients. 
      CONCLUSIONS: These results suggest that USP does not induce generalized 
      hypersensitivity, in contrast with previously reported findings. Physiotherapists 
      could take these results into account for the assessment and treatment of 
      patients with USP.
CI  - Copyright (c) 2021. Published by Elsevier Ltd.
FAU - Intelangelo, Leonardo
AU  - Intelangelo L
AD  - Musculoskeletal Research Unit - UIM, University Center for Assistance, Teaching 
      and Research - CUADI, University of Gran Rosario - UGR, Rosario, Argentina. 
      Electronic address: lintelangelo@ugr.edu.ar.
FAU - Bordachar, Diego
AU  - Bordachar D
AD  - Musculoskeletal Research Unit - UIM, University Center for Assistance, Teaching 
      and Research - CUADI, University of Gran Rosario - UGR, Rosario, Argentina.
FAU - Mendoza, Cristian
AU  - Mendoza C
AD  - Musculoskeletal Research Unit - UIM, University Center for Assistance, Teaching 
      and Research - CUADI, University of Gran Rosario - UGR, Rosario, Argentina.
FAU - Lassaga, Ignacio
AU  - Lassaga I
AD  - Musculoskeletal Research Unit - UIM, University Center for Assistance, Teaching 
      and Research - CUADI, University of Gran Rosario - UGR, Rosario, Argentina.
FAU - Barbosa, Alexandre Carvalho
AU  - Barbosa AC
AD  - Department of Physical Therapy, Musculoskeletal Research Group - NIME, Federal 
      University of Juiz de Fora, Brazil.
FAU - Manresa, Jose Biurrun
AU  - Manresa JB
AD  - Institute for Research and Development on Bioengineering and Bioinformatics 
      (IBB), CONICET-UNER, Oro Verde, Argentina; Center for Neuroplasticity and Pain 
      (CNAP), SMI(R), Faculty of Medicine, Aalborg University, Aalborg, Denmark.
FAU - Mista, Christian
AU  - Mista C
AD  - Institute for Research and Development on Bioengineering and Bioinformatics 
      (IBB), CONICET-UNER, Oro Verde, Argentina.
LA  - eng
PT  - Journal Article
DEP - 20211217
PL  - Netherlands
TA  - Musculoskelet Sci Pract
JT  - Musculoskeletal science & practice
JID - 101692753
SB  - IM
MH  - Humans
MH  - *Pain Threshold/physiology
MH  - Rotator Cuff
MH  - Shoulder
MH  - *Shoulder Pain
OTO - NOTNLM
OT  - Generalized hypersensitivity
OT  - Infraspinatus muscle
OT  - Pressure algometry
OT  - Pressure pain threshold
EDAT- 2022/02/04 06:00
MHDA- 2022/03/26 06:00
CRDT- 2022/02/03 20:15
PHST- 2021/08/25 00:00 [received]
PHST- 2021/11/25 00:00 [revised]
PHST- 2021/12/14 00:00 [accepted]
PHST- 2022/02/04 06:00 [pubmed]
PHST- 2022/03/26 06:00 [medline]
PHST- 2022/02/03 20:15 [entrez]
AID - S2468-7812(21)00179-X [pii]
AID - 10.1016/j.msksp.2021.102495 [doi]
PST - ppublish
SO  - Musculoskelet Sci Pract. 2022 Apr;58:102495. doi: 10.1016/j.msksp.2021.102495. 
      Epub 2021 Dec 17.