PMID- 35125465
OWN - NLM
STAT- MEDLINE
DCOM- 20220603
LR  - 20231001
IS  - 1534-4908 (Electronic)
IS  - 1530-4515 (Linking)
VI  - 32
IP  - 3
DP  - 2022 Jun 1
TI  - Perioperative Outcomes of Laparoscopic Liver Resection and Risk Factors for 
      Adverse Events.
PG  - 305-310
LID - 10.1097/SLE.0000000000001036 [doi]
AB  - PURPOSE: The perioperative outcomes and risk factors associated with adverse 
      events (AEs) after initial laparoscopic liver resection (LLR) are unclear. We 
      studied the outcomes of LLR and identified the predictive factors for AEs. 
      MATERIALS AND METHODS: Data from 100 adults who underwent LLR between April 2014 
      and February 2020 were reviewed. Baseline characteristics, surgery details, 
      intraoperative data, and postoperative outcomes were tabulated. The AEs included 
      conversion to open surgery, morbidity, and mortality. RESULTS: Major and minor 
      LLRs accounted for 16% and 84% of cases, respectively. Of the indications for 
      LLR, 88% were malignancies. Conversion to open surgery was necessary for 7% of 
      the patients, the overall morbidity rate was 21%, the major morbidity rate was 
      7%, and the 90-day mortality rate was 1%. Although the incidence of AEs was 
      higher after major LLR (37.5%) than after minor LLR (21.4%), the difference was 
      not statistically significant (P=0.095); the rate of AEs in the resection of 
      posterosuperior segments (43.7%) did not significantly differ from that of the 
      anteroinferior segments (19.2%; P=0.095). Multivariable analysis revealed that 
      the significant predictors of AEs included American Society of Anesthesiologists 
      (ASA) class III (odds ratio, 5.76; 95% confidence interval, 1.74-19.1; P=0.003) 
      and an operative time longer than 5 hours (odds ratio, 9.20; 95% confidence 
      interval, 2.41-35.07; P<0.001). CONCLUSION: To improve outcomes in LLR, patients 
      with ASA class III and those in whom surgery is expected to last longer than 5 
      hours should be taken into account for better patient selection.
CI  - Copyright (c) 2022 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Wiboonkhwan, Nan-Ak
AU  - Wiboonkhwan NA
AD  - Department of Surgery.
FAU - Thongkan, Tortrakoon
AU  - Thongkan T
AD  - Department of Surgery.
FAU - Sangkhathat, Surasak
AU  - Sangkhathat S
AD  - Department of Surgery.
FAU - Pruphetkaew, Nannapat
AU  - Pruphetkaew N
AD  - Epidemiology Unit, Faculty of Medicine, Prince of Songkla University, Hat Yai, 
      Songkhla Province, Thailand.
FAU - Pitakteerabundit, Thakerng
AU  - Pitakteerabundit T
AD  - Department of Surgery.
LA  - eng
PT  - Journal Article
DEP - 20220601
PL  - United States
TA  - Surg Laparosc Endosc Percutan Tech
JT  - Surgical laparoscopy, endoscopy & percutaneous techniques
JID - 100888751
SB  - IM
MH  - Adult
MH  - *Carcinoma, Hepatocellular/surgery
MH  - Hepatectomy/adverse effects
MH  - Humans
MH  - *Laparoscopy/adverse effects
MH  - Length of Stay
MH  - *Liver Neoplasms
MH  - Postoperative Complications/epidemiology/etiology/surgery
MH  - Retrospective Studies
MH  - Risk Factors
COIS- The authors declare no conflicts of interest.
EDAT- 2022/02/08 06:00
MHDA- 2022/06/07 06:00
CRDT- 2022/02/07 05:27
PHST- 2021/08/27 00:00 [received]
PHST- 2021/11/16 00:00 [accepted]
PHST- 2022/02/08 06:00 [pubmed]
PHST- 2022/06/07 06:00 [medline]
PHST- 2022/02/07 05:27 [entrez]
AID - 00129689-202206000-00004 [pii]
AID - 10.1097/SLE.0000000000001036 [doi]
PST - epublish
SO  - Surg Laparosc Endosc Percutan Tech. 2022 Jun 1;32(3):305-310. doi: 
      10.1097/SLE.0000000000001036.