PMID- 35126196 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231102 IS - 1664-0640 (Print) IS - 1664-0640 (Electronic) IS - 1664-0640 (Linking) VI - 12 DP - 2021 TI - The Need for Psychedelic-Assisted Therapy in the Black Community and the Burdens of Its Provision. PG - 774736 LID - 10.3389/fpsyt.2021.774736 [doi] LID - 774736 AB - Psychedelic medicine is an emerging field that examines entheogens, psychoactive substances that produce non-ordinary states of consciousness (NOSC). 3,4-methylenedioxymethamphetamine (MDMA) is currently in phase-3 FDA clinical trials in the United States (US) and Canada to treat the symptoms of posttraumatic stress disorder (PTSD). MDMA is used in conjunction with manualized therapy, because of its effectiveness in reducing fear-driven stimuli that contribute to trauma and anxiety symptoms. In 2017, the FDA designated MDMA as a "breakthrough therapy," signaling that it has advantages in safety, efficacy, and compliance over available medication for the treatment of trauma-, stress-, and anxiety-related disorders such as PTSD. In the US and Canada, historical and contemporary racial mistreatment is frequently experienced by Black people via a variety of macro and micro insults. Such experiences trigger physiological responses of anxiety and fear, which are associated with chronically elevated stress hormone levels (e.g., cortisol and epinephrine), similar to levels documented among those diagnosed with an anxiety disorder. This paper will explore the benefits of entheogens within psychedelic assisted-therapy and their potential benefits in addressing the sequelae of pervasive and frequent negative race-based experiences and promoting healing and thriving among Black, Indigenous and other People of Color (BIPOC). The author(s) discuss the ethical responsibility for providing psychedelic-assisted therapy within a culturally competent provider framework and the importance of psychedelic researchers to recruit and retain BIPOC populations in research and clinical training. CI - Copyright (c) 2022 Smith, Faber, Buchanan, Foster and Green. FAU - Smith, Darron T AU - Smith DT AD - Department of Sociology, The University of Memphis, Memphis, TN, United States. FAU - Faber, Sonya C AU - Faber SC AD - Bioville GmbH, Leipzig, Germany. FAU - Buchanan, NiCole T AU - Buchanan NT AD - Department of Psychology, Michigan State University, East Lansing, MI, United States. FAU - Foster, Dale AU - Foster D AD - Neuro-Source, Memphis, TN, United States. FAU - Green, Lilith AU - Green L AD - Department of Sociology, The University of Memphis, Memphis, TN, United States. LA - eng PT - Journal Article DEP - 20220120 PL - Switzerland TA - Front Psychiatry JT - Frontiers in psychiatry JID - 101545006 PMC - PMC8811257 OTO - NOTNLM OT - African Americans OT - Black Americans OT - Black Canadian OT - psychedelic research OT - psychedelic-assisted therapy OT - race-based harassment and discrimination OT - racial trauma COIS- SF was employed by the company Bioville GmbH. The remaining authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/02/08 06:00 MHDA- 2022/02/08 06:01 PMCR- 2022/01/20 CRDT- 2022/02/07 05:29 PHST- 2021/09/12 00:00 [received] PHST- 2021/12/14 00:00 [accepted] PHST- 2022/02/07 05:29 [entrez] PHST- 2022/02/08 06:00 [pubmed] PHST- 2022/02/08 06:01 [medline] PHST- 2022/01/20 00:00 [pmc-release] AID - 10.3389/fpsyt.2021.774736 [doi] PST - epublish SO - Front Psychiatry. 2022 Jan 20;12:774736. doi: 10.3389/fpsyt.2021.774736. eCollection 2021.