PMID- 35130814 OWN - NLM STAT- MEDLINE DCOM- 20220406 LR - 20220531 IS - 1744-8360 (Electronic) IS - 1473-7175 (Linking) VI - 22 IP - 2 DP - 2022 Feb TI - Immunopsychiatry: an update on autoimmune encephalitis for neuropsychiatrists. PG - 155-167 LID - 10.1080/14737175.2022.2038136 [doi] AB - INTRODUCTION: Autoimmune encephalitis (AIE) is a group of immune-mediated inflammatory processes of the brain with marked psychiatric features. Although relatively rare, they might offer difficult differential diagnosis with psychiatric conditions, especially catatonia and psychotic syndromes. Anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis is the most common AIE, presenting with psychiatric syndromes in 90% of cases. The associated psychopathology is complex, pleomorphic, and best characterized when there is involvement of a psychiatrist in the assessment. AREAS COVERED: This text will review the main aspects of AIE to psychiatrists and/or neuropsychiatrists. EXPERT OPINION: Immune system dysfunction has been implicated in the pathophysiology of psychiatric symptoms and disorders. The use of diagnostic criteria for possible AIE, especially when specific antibodies of AIE are not available, allows early diagnosis and prompt treatment which are associated with better clinical outcomes. The study of the psychiatric aspects of AIE can broaden our knowledge of the underlying mechanisms of various psychiatric manifestations. FAU - Marques, Frederico Moraes Cardoso AU - Marques FMC AUID- ORCID: 0000-0002-7556-6805 AD - Cognitive and Behavioral Neurology, Department of Clinical Medicine, Federal University of Goias, School of Medicine, Goiania, GO, Brazil. FAU - Nardi, Antonio Egidio AU - Nardi AE AUID- ORCID: 0000-0002-2152-4669 AD - Institute of Psychiatry, Federal University of Rio de Janeiro, School of Medicine, Brazil. FAU - Teixeira, Antonio L AU - Teixeira AL AUID- ORCID: 0000-0002-9621-5422 AD - Neurology and Psychiatry, University of Texas Health Science Center McGovern Medical School, Houston, TX, USA. FAU - Caixeta, Leonardo AU - Caixeta L AUID- ORCID: 0000-0002-5736-9058 AD - Neurology and Neuropsychiatry, Department of Clinical Medicine, Federal University of Goias, School of Medicine, Goiania, GO, Brazil. LA - eng PT - Journal Article DEP - 20220221 PL - England TA - Expert Rev Neurother JT - Expert review of neurotherapeutics JID - 101129944 RN - 0 (Receptors, N-Methyl-D-Aspartate) SB - IM MH - *Anti-N-Methyl-D-Aspartate Receptor Encephalitis/diagnosis/psychology MH - *Catatonia/complications MH - *Hashimoto Disease/diagnosis/psychology MH - Humans MH - *Mental Disorders/complications MH - Psychiatry MH - Receptors, N-Methyl-D-Aspartate OTO - NOTNLM OT - *Immunopsychiatry OT - *autoimmune encephalitis OT - *catatonia OT - *neuropsychiatry OT - *psychopathology EDAT- 2022/02/09 06:00 MHDA- 2022/04/07 06:00 CRDT- 2022/02/08 05:37 PHST- 2022/02/09 06:00 [pubmed] PHST- 2022/04/07 06:00 [medline] PHST- 2022/02/08 05:37 [entrez] AID - 10.1080/14737175.2022.2038136 [doi] PST - ppublish SO - Expert Rev Neurother. 2022 Feb;22(2):155-167. doi: 10.1080/14737175.2022.2038136. Epub 2022 Feb 21.