PMID- 35144606
OWN - NLM
STAT- MEDLINE
DCOM- 20220406
LR  - 20220406
IS  - 1746-6148 (Electronic)
IS  - 1746-6148 (Linking)
VI  - 18
IP  - 1
DP  - 2022 Feb 10
TI  - 3T high-resolution magnetic resonance imaging, conventional ultrasonography and 
      ultrasound biomicroscopy of the normal canine eye.
PG  - 67
LID - 10.1186/s12917-021-03108-0 [doi]
LID - 67
AB  - BACKGROUND: Advances in MRI coil technology and increased availability of 
      high-field MRI in veterinary medicine enable the acquisition of images of 
      increasingly high spatial resolution while preserving signal-to-noise ratio.The 
      purpose of the present study was to compare 3T high-resolution magnetic resonance 
      imaging (HR-MRI) with ultrasound (US) and ultrasound biomicroscopy (UBM) in the 
      normal canine eye, to assess its potential to depict normal ocular anatomy. 
      RESULTS: HR-MRI was compared with US and UBM in 10 eyes from 10 healthy beagle 
      dogs. Ocular structures (cornea, anterior chamber, iridocorneal angle, iris, 
      lens, ciliary body, choroid, vitreous body, posterior wall of the eye, optic 
      nerve and optic nerve sheath, extraocular muscles) were assessed subjectively and 
      central corneal thickness (CCT), anterior chamber depth (ACD), aqueous depth 
      (AQD), anteroposterior, mediolateral and dorsoventral lens diameter (APLD, MLLD, 
      DVLD), anteroposterior diameter of the globe including and excluding the 
      scleroretinal rim (APDSRR, APD), vitreous chamber depth (VCD) and optic nerve 
      sheath diameter (ONSD) were measured in HR-MRI and in US. Optic nerve diameter 
      (OND) was measured in HR-MRI. HR-MRI and UBM appearance of the anterior segment 
      were subjectively compared. Detailed reference high-resolution MRI images of 
      normal eyes of Beagle dogs are provided. CONCLUSIONS: HR-MRI allowed assessment 
      of all structures identified with US and UBM. The MRI examinations were performed 
      under general anesthesia with the addition of a neuromuscular blocking agent, 
      while US and UBM examinations were performed in conscious animals. Visibility of 
      the entire ocular wall, the lens, the structures caudal to the ciliary body and 
      the optic nerve and its sheath was superior with HR-MRI. HR-MRI allowed the 
      distinction of retina, choroid and sclera, and the delineation of structures not 
      previously identified in canine eyes with MRI, including Tenon's capsule and the 
      sub-Tenon's space.Plane selection was more accurate with HR-MRI compared to US. 
      In general, the range of measurements was narrower for MRI than for US. CCT, AQD, 
      APLD, MLLD, APD, APDSRR and ONSD differed significantly between HR-MRI and US, 
      respectively (p = 0.005-0.027).Micro-MRI may be useful for the assessment of 
      ocular pathologies in the future.
CI  - (c) 2022. The Author(s).
FAU - Ivan, Daniel
AU  - Ivan D
AD  - Clinic for Diagnostic Imaging, Department for Clinical Diagnostics and Services, 
      Vetsuisse Faculty, University of Zurich, Zurich, Switzerland. 
      ivandanielmv@yahoo.com.
FAU - Ohlerth, Stefanie
AU  - Ohlerth S
AD  - Clinic for Diagnostic Imaging, Department for Clinical Diagnostics and Services, 
      Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
FAU - Richter, Henning
AU  - Richter H
AD  - Clinic for Diagnostic Imaging, Department for Clinical Diagnostics and Services, 
      Vetsuisse Faculty, University of Zurich, Zurich, Switzerland.
FAU - Verdino, Dagmar
AU  - Verdino D
AD  - Veterinary Anesthesia Services International GmbH, Winterthur, Switzerland.
FAU - Rampazzo, Antonella
AU  - Rampazzo A
AD  - Ophthalmology Section, Equine Department, Vetsuisse Faculty, Zurich, Switzerland.
FAU - Pot, Simon
AU  - Pot S
AD  - Ophthalmology Section, Equine Department, Vetsuisse Faculty, Zurich, Switzerland.
LA  - eng
PT  - Journal Article
DEP - 20220210
PL  - England
TA  - BMC Vet Res
JT  - BMC veterinary research
JID - 101249759
SB  - IM
MH  - Animals
MH  - *Anterior Eye Segment/anatomy & histology/diagnostic imaging
MH  - Cornea/anatomy & histology
MH  - Dogs
MH  - Magnetic Resonance Imaging/veterinary
MH  - *Microscopy, Acoustic/methods/veterinary
MH  - Ultrasonography/veterinary
PMC - PMC8829979
OTO - NOTNLM
OT  - 3 Tesla
OT  - Dog
OT  - Eye
OT  - HR-MRI
OT  - MRI microscopy
OT  - Microcoil
OT  - Ultrasound
OT  - Ultrasound biomicroscopy
COIS- The authors declare that they have no competing interests.
EDAT- 2022/02/12 06:00
MHDA- 2022/04/07 06:00
PMCR- 2022/02/10
CRDT- 2022/02/11 05:30
PHST- 2021/08/28 00:00 [received]
PHST- 2021/12/03 00:00 [accepted]
PHST- 2022/02/11 05:30 [entrez]
PHST- 2022/02/12 06:00 [pubmed]
PHST- 2022/04/07 06:00 [medline]
PHST- 2022/02/10 00:00 [pmc-release]
AID - 10.1186/s12917-021-03108-0 [pii]
AID - 3108 [pii]
AID - 10.1186/s12917-021-03108-0 [doi]
PST - epublish
SO  - BMC Vet Res. 2022 Feb 10;18(1):67. doi: 10.1186/s12917-021-03108-0.