PMID- 35147773 OWN - NLM STAT- MEDLINE DCOM- 20221125 LR - 20221125 IS - 1613-7671 (Electronic) IS - 0043-5325 (Linking) VI - 134 IP - 21-22 DP - 2022 Nov TI - Recurrent gestational diabetes : Breaking the transgenerational cycle with lifestyle modification. PG - 788-798 LID - 10.1007/s00508-022-02004-3 [doi] AB - PURPOSE: This literature review is aimed at examining the benefits of lifestyle modifications in preventing recurrent gestational diabetes (GDM). Worldwide GDM affects approximately 16.2% of all pregnancies with significant maternal, fetal and neonatal complications. Almost two thirds of pregnant women with GDM will develop type 2 diabetes mellitus (T2DM) in the years following pregnancy. The proportion of women affected by GDM is on the rise and reflects increasing trends in T2DM as well as adult and childhood obesity. METHODS: Using predefined subject headings, we searched for relevant articles from the PubMed, Scopus, and Cochrane databases. RESULTS: For high-risk women lifestyle modifications, such as dietary and exercise changes, are the mainstay of treatment to reduce negative outcomes for both women and their pregnancies. This includes reducing the incidence of recurrent GDM and future T2DM by intervening during pregnancy and in the postnatal period. CONCLUSION: This review provides an overview of the literature to date, discusses different targeted approaches and how these interventions can optimise their benefits, and where further research is required. CI - (c) 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature. FAU - Liney, Thomas AU - Liney T AD - The Hillingdon Hospitals NHS Foundation Trust, Pield Heath Road, UB8 3NN, Uxbridge, UK. FAU - Shah, Nishel M AU - Shah NM AUID- ORCID: 0000-0002-5694-9915 AD - Imperial College London, Academic Department of Obstetrics & Gynaecology, Level 3, Chelsea and Westminster Hospital, 369 Fulham Road, SW10 9NH, London, UK. FAU - Singh, Natasha AU - Singh N AUID- ORCID: 0000-0002-5130-9679 AD - Imperial College London, Academic Department of Obstetrics & Gynaecology, Level 3, Chelsea and Westminster Hospital, 369 Fulham Road, SW10 9NH, London, UK. n.mohammed@imperial.ac.uk. LA - eng PT - Letter PT - Review DEP - 20220211 PL - Austria TA - Wien Klin Wochenschr JT - Wiener klinische Wochenschrift JID - 21620870R SB - IM MH - Child MH - Infant, Newborn MH - Adult MH - Female MH - Pregnancy MH - Humans MH - *Diabetes, Gestational/diagnosis/prevention & control MH - *Diabetes Mellitus, Type 2/diagnosis/prevention & control MH - *Pediatric Obesity MH - Life Style MH - Exercise OTO - NOTNLM OT - Diabetes mellitus OT - Gestational diabetes OT - Lifestyle modifications OT - Obesity OT - Pregnancy EDAT- 2022/02/12 06:00 MHDA- 2022/11/26 06:00 CRDT- 2022/02/11 12:13 PHST- 2021/07/22 00:00 [received] PHST- 2022/01/09 00:00 [accepted] PHST- 2022/02/12 06:00 [pubmed] PHST- 2022/11/26 06:00 [medline] PHST- 2022/02/11 12:13 [entrez] AID - 10.1007/s00508-022-02004-3 [pii] AID - 10.1007/s00508-022-02004-3 [doi] PST - ppublish SO - Wien Klin Wochenschr. 2022 Nov;134(21-22):788-798. doi: 10.1007/s00508-022-02004-3. Epub 2022 Feb 11.