PMID- 35151622
OWN - NLM
STAT- MEDLINE
DCOM- 20240108
LR  - 20240326
IS  - 2531-0437 (Electronic)
IS  - 2531-0429 (Linking)
VI  - 30
IP  - 1
DP  - 2024 Jan-Feb
TI  - Unsupervised physical activity interventions for people with COPD: A systematic 
      review and meta-analysis.
PG  - 53-67
LID - S2531-0437(22)00016-2 [pii]
LID - 10.1016/j.pulmoe.2022.01.007 [doi]
AB  - INTRODUCTION AND OBJECTIVES: Unsupervised PA interventions might have a role in 
      the management of chronic obstructive pulmonary disease (COPD) but their 
      effectiveness is largely unknown. Thus, we aimed to identify and synthesise data 
      on the effects of unsupervised PA interventions in people with COPD. MATERIAL AND 
      METHODS: Databases were systematically searched in April 2020, with weekly 
      updates until September 2021. Randomised controlled trials and quasi-experimental 
      studies comparing unsupervised PA with usual care, were included. Primary 
      outcomes were dyspnoea, exercise capacity and physical activity. The effect 
      direction plot was performed to synthesise results. Meta-analysis with forest 
      plots were conducted for the Chronic Respiratory Disease questionnaire - dyspnoea 
      domain (CRQ-D), 6-minute walk distance (6MWD) and incremental shuttle walk 
      distance (ISWD). RESULTS: Eleven studies with 900 participants with COPD (68+/-10 
      years; 58.8% male, FEV(1) 63.7+/-15.8% predicted) were included. All interventions 
      were conducted at home, most with daily sessions, for 8-12 weeks. Walking was the 
      most common component. The effect direction plot showed that unsupervised PA 
      interventions improved emotional function, fatigue, health-related quality of 
      life, muscle strength and symptoms of anxiety and depression. Meta-analysis 
      showed statistical, but not clinical, significant improvements in dyspnoea 
      (CRQ-D, MD=0.12, 95% CI 0.09-0.15) and exercise capacity, measured with 6MWD 
      (MD=13.70, 95% CI 3.58-23.83). Statistical and clinical significant improvements 
      were observed in exercise capacity, measured with ISWD (MD=58.59, 95% CI 
      5.79-111.39). None to minor adverse events and a high adherence rate were found. 
      CONCLUSIONS: Unsupervised PA interventions benefits dyspnoea and exercise 
      capacity of people with COPD, are safe and present a high adherence rate. 
      Unsupervised PA interventions should be considered for people with COPD who 
      cannot or do not want to engage in supervised PA interventions or as a 
      maintenance strategy of PA levels.
CI  - Copyright (c) 2022 Sociedade Portuguesa de Pneumologia. Published by Elsevier 
      Espana, S.L.U. All rights reserved.
FAU - Paixao, C
AU  - Paixao C
AD  - Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health 
      Sciences (ESSUA), University of Aveiro, Aveiro, Portugal; iBiMED - Institute of 
      Biomedicine, University of Aveiro, Aveiro, Portugal; Department of Medical 
      Sciences, University of Aveiro, Aveiro, Portugal.
FAU - Rocha, V
AU  - Rocha V
AD  - Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health 
      Sciences (ESSUA), University of Aveiro, Aveiro, Portugal; iBiMED - Institute of 
      Biomedicine, University of Aveiro, Aveiro, Portugal.
FAU - Brooks, D
AU  - Brooks D
AD  - School of Rehabilitation Sciences, McMaster University, Hamilton, Canada; West 
      Park Healthcare Centre, Toronto, Canada.
FAU - Marques, A
AU  - Marques A
AD  - Lab3R - Respiratory Research and Rehabilitation Laboratory, School of Health 
      Sciences (ESSUA), University of Aveiro, Aveiro, Portugal; iBiMED - Institute of 
      Biomedicine, University of Aveiro, Aveiro, Portugal. Electronic address: 
      amarques@ua.pt.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
DEP - 20220209
PL  - Spain
TA  - Pulmonology
JT  - Pulmonology
JID - 101723786
SB  - IM
MH  - Female
MH  - Humans
MH  - Male
MH  - Dyspnea/therapy
MH  - *Exercise
MH  - *Pulmonary Disease, Chronic Obstructive/therapy/psychology
MH  - *Quality of Life
OTO - NOTNLM
OT  - COPD
OT  - Meta-analysis
OT  - Physical activity
OT  - Systematic review
OT  - Unsupervised
EDAT- 2022/02/14 06:00
MHDA- 2024/01/08 06:42
CRDT- 2022/02/13 20:28
PHST- 2021/10/08 00:00 [received]
PHST- 2022/01/09 00:00 [revised]
PHST- 2022/01/10 00:00 [accepted]
PHST- 2024/01/08 06:42 [medline]
PHST- 2022/02/14 06:00 [pubmed]
PHST- 2022/02/13 20:28 [entrez]
AID - S2531-0437(22)00016-2 [pii]
AID - 10.1016/j.pulmoe.2022.01.007 [doi]
PST - ppublish
SO  - Pulmonology. 2024 Jan-Feb;30(1):53-67. doi: 10.1016/j.pulmoe.2022.01.007. Epub 
      2022 Feb 9.