PMID- 35155373
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220216
IS  - 2296-2646 (Print)
IS  - 2296-2646 (Electronic)
IS  - 2296-2646 (Linking)
VI  - 10
DP  - 2022
TI  - Research Progress of UiO-66-Based Electrochemical Biosensors.
PG  - 842894
LID - 10.3389/fchem.2022.842894 [doi]
LID - 842894
AB  - UiO-66, as a member of the MOFs families, is widely employed in sensing, drug 
      release, separation, and adsorption due to its large specific surface area, 
      uniform pore size, easy functionalization, and excellent stability. Especially in 
      electrochemical biosensors, UiO-66 has demonstrated excellent adsorption capacity 
      and response signal, which significantly improves the sensitivity and specificity 
      of detection. However, the existing application research remains in its infancy, 
      lacking systematic methods, and recycling utilization and exclusive sensing of 
      UiO-66 still require further improvement. Therefore, one of the present research 
      objectives is to explore the breakthrough point of existing technologies and 
      optimize the performance of UiO-66-based electrochemical biosensors (UiO-66-EBs). 
      In this work, we summarized current experimental methods and detection mechanisms 
      of UiO-66-EBs in environmental detection, food safety, and disease diagnosis, 
      analyzed the existing problems, and proposed some suggestions to provide new 
      ideas for future research.
CI  - Copyright (c) 2022 Wu, Zhang, Zhang, Wang, Wang, Liu, Guo and Song.
FAU - Wu, Ming
AU  - Wu M
AD  - Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, 
      Ministry of Education, College of Life Science, Jilin Agricultural University, 
      Changchun, China.
FAU - Zhang, Qi
AU  - Zhang Q
AD  - Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, 
      Ministry of Education, College of Life Science, Jilin Agricultural University, 
      Changchun, China.
FAU - Zhang, Qiuyu
AU  - Zhang Q
AD  - Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, 
      Ministry of Education, College of Life Science, Jilin Agricultural University, 
      Changchun, China.
FAU - Wang, Huan
AU  - Wang H
AD  - College of Food Science and Engineering, Jilin Agricultural University, 
      Changchun, China.
FAU - Wang, Fawei
AU  - Wang F
AD  - Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, 
      Ministry of Education, College of Life Science, Jilin Agricultural University, 
      Changchun, China.
AD  - College of Life Sciences, Engineering Research Center of the Chinese Ministry of 
      Education for Bioreactor and Pharmaceutical Development, Jilin Agricultural 
      University, Changchun, China.
FAU - Liu, Junmei
AU  - Liu J
AD  - College of Food Science and Engineering, Jilin Agricultural University, 
      Changchun, China.
FAU - Guo, Liquan
AU  - Guo L
AD  - Key Laboratory of Straw Comprehensive Utilization and Black Soil Conservation, 
      Ministry of Education, College of Life Science, Jilin Agricultural University, 
      Changchun, China.
FAU - Song, Kai
AU  - Song K
AD  - School of Life Science, Changchun Normal University, Changchun, China.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20220126
PL  - Switzerland
TA  - Front Chem
JT  - Frontiers in chemistry
JID - 101627988
PMC - PMC8825417
OTO - NOTNLM
OT  - UiO-66
OT  - biomedical
OT  - electrochemical biosensor
OT  - environmental
OT  - food safety
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/02/15 06:00
MHDA- 2022/02/15 06:01
PMCR- 2022/01/01
CRDT- 2022/02/14 05:34
PHST- 2021/12/24 00:00 [received]
PHST- 2022/01/05 00:00 [accepted]
PHST- 2022/02/14 05:34 [entrez]
PHST- 2022/02/15 06:00 [pubmed]
PHST- 2022/02/15 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 842894 [pii]
AID - 10.3389/fchem.2022.842894 [doi]
PST - epublish
SO  - Front Chem. 2022 Jan 26;10:842894. doi: 10.3389/fchem.2022.842894. eCollection 
      2022.