PMID- 35161920 OWN - NLM STAT- MEDLINE DCOM- 20220216 LR - 20220219 IS - 1424-8220 (Electronic) IS - 1424-8220 (Linking) VI - 22 IP - 3 DP - 2022 Feb 4 TI - Cuffless Blood Pressure Estimation Based on Monte Carlo Simulation Using Photoplethysmography Signals. LID - 10.3390/s22031175 [doi] LID - 1175 AB - Blood pressure measurements are one of the most routinely performed medical tests globally. Blood pressure is an important metric since it provides information that can be used to diagnose several vascular diseases. Conventional blood pressure measurement systems use cuff-based devices to measure the blood pressure, which may be uncomfortable and sometimes burdensome to the subjects. Therefore, in this study, we propose a cuffless blood pressure estimation model based on Monte Carlo simulation (MCS). We propose a heterogeneous finger model for the MCS at wavelengths of 905 nm and 940 nm. After recording the photon intensities from the MCS over a certain range of blood pressure values, the actual photoplethysmography (PPG) signals were used to estimate blood pressure. We used both publicly available and self-made datasets to evaluate the performance of the proposed model. In case of the publicly available dataset for transmission-type MCS, the mean absolute errors are 3.32 +/- 6.03 mmHg for systolic blood pressure (SBP), 2.02 +/- 2.64 mmHg for diastolic blood pressure (DBP), and 1.76 +/- 2.8 mmHg for mean arterial pressure (MAP). The self-made dataset is used for both transmission- and reflection-type MCSs; its mean absolute errors are 2.54 +/- 4.24 mmHg for SBP, 1.49 +/- 2.82 mmHg for DBP, and 1.51 +/- 2.41 mmHg for MAP in the transmission-type case as well as 3.35 +/- 5.06 mmHg for SBP, 2.07 +/- 2.83 mmHg for DBP, and 2.12 +/- 2.83 mmHg for MAP in the reflection-type case. The estimated results of the SBP and DBP satisfy the requirements of the Association for the Advancement of Medical Instrumentation (AAMI) standards and are within Grade A according to the British Hypertension Society (BHS) standards. These results show that the proposed model is efficient for estimating blood pressures using fingertip PPG signals. FAU - Haque, Chowdhury Azimul AU - Haque CA AUID- ORCID: 0000-0002-3947-1454 AD - Department of Electronics Engineering, Kookmin University, Seoul 02707, Korea. FAU - Kwon, Tae-Ho AU - Kwon TH AUID- ORCID: 0000-0001-6784-5591 AD - Department of Electronics Engineering, Kookmin University, Seoul 02707, Korea. FAU - Kim, Ki-Doo AU - Kim KD AUID- ORCID: 0000-0001-5052-3844 AD - Department of Electronics Engineering, Kookmin University, Seoul 02707, Korea. LA - eng GR - 2015R1A5A7037615/National Research Foundation of Korea/ GR - NRF-2019R1F1A1062317/National Research Foundation of Korea/ PT - Journal Article DEP - 20220204 PL - Switzerland TA - Sensors (Basel) JT - Sensors (Basel, Switzerland) JID - 101204366 SB - IM MH - Blood Pressure MH - Blood Pressure Determination MH - Humans MH - *Hypertension/diagnosis MH - Monte Carlo Method MH - *Photoplethysmography PMC - PMC8838459 OTO - NOTNLM OT - Monte Carlo simulation OT - blood pressure OT - cuffless OT - machine learning OT - photoplethysmography COIS- The authors hereby declare that they have no conflict of interest. The funders had no role in the design of the study; in the collection, analyses, or interpretation of data; in the writing of the manuscript, or in the publication of the results. EDAT- 2022/02/16 06:00 MHDA- 2022/02/17 06:00 PMCR- 2022/02/04 CRDT- 2022/02/15 01:12 PHST- 2022/01/03 00:00 [received] PHST- 2022/01/28 00:00 [revised] PHST- 2022/01/29 00:00 [accepted] PHST- 2022/02/15 01:12 [entrez] PHST- 2022/02/16 06:00 [pubmed] PHST- 2022/02/17 06:00 [medline] PHST- 2022/02/04 00:00 [pmc-release] AID - s22031175 [pii] AID - sensors-22-01175 [pii] AID - 10.3390/s22031175 [doi] PST - epublish SO - Sensors (Basel). 2022 Feb 4;22(3):1175. doi: 10.3390/s22031175.