PMID- 35162396 OWN - NLM STAT- MEDLINE DCOM- 20220228 LR - 20220228 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 19 IP - 3 DP - 2022 Jan 26 TI - Geographic and Ethnic Variations in Serum Concentrations of Legacy Persistent Organic Pollutants among Men in the Nenets Autonomous Okrug, Arctic Russia. LID - 10.3390/ijerph19031379 [doi] LID - 1379 AB - The overwhelming majority of Arctic biomonitoring studies in humans include either pregnant or non-pregnant women of reproductive age while little attention is paid to toxic compounds concentrations in men. This study contributes with information of the present amounts of persistent organic pollutants (POPs) in men living in Arctic Russia. We studied the serum concentrations of 11 polychlorinated biphenyl (PCB) congeners and 17 organochlorine pesticides (OCPs) and some of their metabolites in samples collected from 92 adult men (mean age 43 years) from seven different settlements in Nenets Autonomous Okrug (NAO). The median concentrations of individual PCB congeners increased in the order PCB 183, PCB 180, PCB 118, PCB 138, PCB 153. The concentrations of o, p'-DDD, p, p'-DDD, aldrin, mirex and 1,2,3,5-TCB were in most cases below the quantification limit. The observed concentrations of PCBs and chlorinated pesticides were in the same range as those found in similar groups of women of these territories, but lower than of men in other Arctic countries. However, significant geographic differences between the settlements were observed with exceptionally high concentrations of PCBs in the Islands group. The highest serum summation operatorPCBs and beta-HCH levels were observed in adult males aged 60-78 years. We found significant variations in serum concentrations of POPs across settlements and ethnic groups with exceptionally high concentrations of PCBs among the residents of the Arctic islands. At the same time, our findings suggest a considerable decrease in serum concentration of POPs over the last decade. FAU - Varakina, Yulia AU - Varakina Y AUID- ORCID: 0000-0002-7531-9193 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Aksenov, Andrey AU - Aksenov A AUID- ORCID: 0000-0003-1013-1357 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Lakhmanov, Dmitry AU - Lakhmanov D AD - Laboratory of Environmental Analytical Chemistry, Core Facility Center "Arktika", Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Trofimova, Anna AU - Trofimova A AUID- ORCID: 0000-0001-7271-2283 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Korobitsyna, Rimma AU - Korobitsyna R AUID- ORCID: 0000-0003-0882-1615 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Belova, Natalia AU - Belova N AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. AD - Northern State Medical University, Troitskiy Ave. 51, 163000 Arkhangelsk, Russia. FAU - Kotsur, Dmitry AU - Kotsur D AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. AD - N. Laverov Federal Center for Integrated Arctic Research, Ural Branch of the Russian Academy of Sciences, Naberezhnaya Severnoy Dvini 23, 163000 Arkhangelsk, Russia. FAU - Sorokina, Tatiana AU - Sorokina T AUID- ORCID: 0000-0002-4873-8747 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Grjibovski, Andrej M AU - Grjibovski AM AUID- ORCID: 0000-0002-5464-0498 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. AD - Northern State Medical University, Troitskiy Ave. 51, 163000 Arkhangelsk, Russia. AD - Department of Epidemiology and Modern Vaccination Technology, I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya Str., 8-2, 119991 Moscow, Russia. AD - West Kazakhstan Marat Ospanov Medical University, Aktobe 0300190, Kazakhstan. FAU - Popova, Ludmila AU - Popova L AD - Department of Chemistry and Chemical Ecology, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. FAU - Chashchin, Valery AU - Chashchin V AUID- ORCID: 0000-0002-2600-0522 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. AD - North-Western State Medical University Named after I. I. Mechnikov, Kirochnaya ul. 41, 191015 Saint-Petersburg, Russia. AD - Institute of Ecology, National Research University Higher School of Economics, Myasnitskaya Str. 20, 101000 Moscow, Russia. FAU - Odland, Jon Oyvind AU - Odland JO AD - Department of Public Health and Nursing, Norwegian University of Science and Technology, 7491 Trondheim, Norway. AD - Department of General Hygiene, I.M. Sechenov First Moscow State Medical University (Sechenov University), Trubetskaya Str., 8-2, 119992 Moscow, Russia. FAU - Thomassen, Yngvar AU - Thomassen Y AUID- ORCID: 0000-0001-7334-6385 AD - Arctic Biomonitoring Laboratory, Northern (Arctic) Federal University Named after M. V. Lomonosov, Naberezhnaya Severnoy Dvini 17, 163002 Arkhangelsk, Russia. AD - Institute of Ecology, National Research University Higher School of Economics, Myasnitskaya Str. 20, 101000 Moscow, Russia. AD - National Institute of Occupational Health, Gydas vei 8, N-0304 Oslo, Norway. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220126 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 RN - 0 (Environmental Pollutants) RN - 0 (Hydrocarbons, Chlorinated) RN - 0 (Pesticides) RN - DFC2HB4I0K (Polychlorinated Biphenyls) SB - IM MH - Adult MH - Aged MH - Environmental Monitoring MH - *Environmental Pollutants/analysis MH - Ethnicity MH - Female MH - Humans MH - *Hydrocarbons, Chlorinated/analysis MH - Male MH - Middle Aged MH - Persistent Organic Pollutants MH - *Pesticides/analysis MH - *Polychlorinated Biphenyls MH - Pregnancy PMC - PMC8835178 OTO - NOTNLM OT - PCBs OT - Russian Arctic OT - biomonitoring OT - indigenous peoples OT - men OT - pesticides COIS- The authors declare that there is no conflict of interest related to the publication of this article that should be reported. EDAT- 2022/02/16 06:00 MHDA- 2022/03/01 06:00 PMCR- 2022/01/26 CRDT- 2022/02/15 01:13 PHST- 2021/12/01 00:00 [received] PHST- 2022/01/19 00:00 [revised] PHST- 2022/01/25 00:00 [accepted] PHST- 2022/02/15 01:13 [entrez] PHST- 2022/02/16 06:00 [pubmed] PHST- 2022/03/01 06:00 [medline] PHST- 2022/01/26 00:00 [pmc-release] AID - ijerph19031379 [pii] AID - ijerph-19-01379 [pii] AID - 10.3390/ijerph19031379 [doi] PST - epublish SO - Int J Environ Res Public Health. 2022 Jan 26;19(3):1379. doi: 10.3390/ijerph19031379.