PMID- 35166727 OWN - NLM STAT- MEDLINE DCOM- 20220217 LR - 20220217 IS - 2038-2502 (Electronic) IS - 0035-6484 (Linking) VI - 57 IP - 1 DP - 2022 Jan-Feb TI - Gender modulation of psychopathological dimensions associated to suicidality. PG - 23-32 LID - 10.1708/3749.37324 [doi] AB - OBJECTIVES: The dimensional approach to psychopathology has been proposed to reliably evaluate suicidality. Potential gender modulation of psychopathological dimensions associated to suicide attempts was investigated. METHODS: 91 subjects who committed a near-lethal suicide (SA group) and 374 who did not (nSA group) were recruited in a Psychiatric Intensive Care Unit regardless of their categorical diagnosis. The Hamilton Depression Rating Scale (HAM-D), the Brief Psychiatric Rating Scale - Expanded version (BPRS-E) and the Scale for Rapid Dimensional Evaluation (SVARAD) were administered at the admission. A Factorial Multivariate ANOVA was conducted according to General Linear Model: Sex and Suicidality were input as fixed factors, HAM-D, BPRS-E and SVARAD scores as dependent variables. RESULTS: Men with SA (MSA) displayed significant lower scores in SVARAD Activation dimension compared to women with SA (FSA) (p=0.049), men without SA (MnSA) (p<0.001) and women without SA (FnSA) (p<0.001). Both SA groups displayed significant higher scores compared to nSA groups in regard of Depression item (BPRS-E) (p<0,001). The MSA group displayed significant lower scores in Psychomotor agitation (HAM-D) compared to FSA (p=0,044), MnSA (p<0,001) and FnSA (p<0,001). CONCLUSIONS: By means of multifactorial statistics sex resulted a moderator of the relation between activation/agitation and suicidality, despite categorical diagnosis. FAU - Accinni, Tommaso AU - Accinni T AD - Department of Human Neurosciences, Sapienza University of Rome, Italy. FAU - Frascarelli, Marianna AU - Frascarelli M AD - Department of Human Neurosciences, Sapienza University of Rome, Italy. FAU - Vecchioni, Sofia AU - Vecchioni S AD - Department of Human Neurosciences, Sapienza University of Rome, Italy. FAU - Tarsitani, Lorenzo AU - Tarsitani L AD - Department of Human Neurosciences, Sapienza University of Rome, Italy. FAU - Biondi, Massimo AU - Biondi M AD - Department of Human Neurosciences, Sapienza University of Rome, Italy. FAU - Pasquini, Massimo AU - Pasquini M AD - Department of Human Neurosciences, Sapienza University of Rome, Italy. LA - eng PT - Journal Article PL - Italy TA - Riv Psichiatr JT - Rivista di psichiatria JID - 0425672 SB - IM MH - Brief Psychiatric Rating Scale MH - Female MH - Humans MH - Male MH - *Mental Disorders MH - Psychiatric Status Rating Scales MH - Psychopathology MH - *Suicide MH - Suicide, Attempted EDAT- 2022/02/16 06:00 MHDA- 2022/02/19 06:00 CRDT- 2022/02/15 12:17 PHST- 2022/02/15 12:17 [entrez] PHST- 2022/02/16 06:00 [pubmed] PHST- 2022/02/19 06:00 [medline] AID - 10.1708/3749.37324 [doi] PST - ppublish SO - Riv Psichiatr. 2022 Jan-Feb;57(1):23-32. doi: 10.1708/3749.37324.