PMID- 35168877 OWN - NLM STAT- MEDLINE DCOM- 20221101 LR - 20221228 IS - 1878-3562 (Electronic) IS - 1590-8658 (Linking) VI - 54 IP - 11 DP - 2022 Nov TI - Efficacy and safety of cold snare polypectomy for sessile serrated polyps >/= 10 mm: A systematic review and meta-analysis. PG - 1486-1493 LID - S1590-8658(22)00143-8 [pii] LID - 10.1016/j.dld.2022.01.132 [doi] AB - BACKGROUND: Cold snare polypectomy (CSP) is a promising technique for the removal of sessile serrated polyps (SSPs) >/= 10 mm. However, the efficacy and safety of this technique remain undetermined. AIMS: We aimed to comprehensively evaluate the efficacy and safety of CSP for SSPs >/= 10 mm. METHODS: PubMed, EMBASE, Web of Science and Cochrane Library were searched up to January 2021. RESULTS: A total of 10 studies consisting of 1727 SSPs (range, 10-40 mm) from 1021 patients were included. The overall rates of technical success, adverse events (AEs) and residual SSPs were 100%, 0.7% and 2.9%, respectively. Subgroup analysis showed that the rates of technical success and AEs were comparable between CSP and cold endoscopic mucosal resection (EMR) (99.9% vs. 100% and 1.3% vs. 0.5%, respectively), between the proximal and distal colon (100% vs. 99.9% and 0.3% vs. 0, respectively), and between polyps of 10-19 mm and >/=20 mm (99.8% vs. 100% and 0.9% vs. 0, respectively). However, subgroup analysis showed that the rate of residual SSPs was slightly lower in CSP compared with cold EMR (1.3% vs. 3.9%), as well as in polyps of 10-19 mm compared with those >/=20 mm (3.1% vs. 4.7%). CONCLUSION: CSP was an effective and safe technique for removing SSPs >/= 10 mm. CI - Copyright (c) 2022. Published by Elsevier Ltd. FAU - Li, De-Feng AU - Li DF AD - Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), No.1017, Dongmen North Road, Luohu District, Shenzhen, Guangdong 518020, China. FAU - Van Overbeke, Lode AU - Van Overbeke L AD - AZ St-Maarten, Gastroenterology, Mechelen 2800, Belgium. FAU - Ohata, Ken AU - Ohata K AD - Department of Gastrointestinal Endoscopy, NTT Medical Center Tokyo, Shinagawa-ku, Tokyo 141-8625, Japan. FAU - Wang, Li-Sheng AU - Wang LS AD - Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), No.1017, Dongmen North Road, Luohu District, Shenzhen, Guangdong 518020, China. Electronic address: wanglsszrmyy@163.com. FAU - Yao, Jun AU - Yao J AD - Department of Gastroenterology, Shenzhen People's Hospital (The Second Clinical Medical College, Jinan University, The First Affiliated Hospital, Southern University of Science and Technology), No.1017, Dongmen North Road, Luohu District, Shenzhen, Guangdong 518020, China. Electronic address: jy_1108@126.com. LA - eng PT - Journal Article PT - Meta-Analysis PT - Review PT - Systematic Review DEP - 20220212 PL - Netherlands TA - Dig Liver Dis JT - Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver JID - 100958385 SB - IM MH - Humans MH - *Colonic Polyps/surgery MH - Colonoscopy/methods MH - *Adenoma/surgery MH - *Endoscopic Mucosal Resection/adverse effects/methods MH - *Colorectal Neoplasms/surgery/etiology MH - *Gastrointestinal Neoplasms OTO - NOTNLM OT - Cold snare polypectomy OT - Meta-analysis OT - Sessile serrated adenomas/polyps COIS- Conflict of interest None declared. EDAT- 2022/02/17 06:00 MHDA- 2022/11/02 06:00 CRDT- 2022/02/16 05:37 PHST- 2021/06/29 00:00 [received] PHST- 2022/01/22 00:00 [revised] PHST- 2022/01/25 00:00 [accepted] PHST- 2022/02/17 06:00 [pubmed] PHST- 2022/11/02 06:00 [medline] PHST- 2022/02/16 05:37 [entrez] AID - S1590-8658(22)00143-8 [pii] AID - 10.1016/j.dld.2022.01.132 [doi] PST - ppublish SO - Dig Liver Dis. 2022 Nov;54(11):1486-1493. doi: 10.1016/j.dld.2022.01.132. Epub 2022 Feb 12.