PMID- 35169397
OWN - NLM
STAT- MEDLINE
DCOM- 20220315
LR  - 20231110
IS  - 1748-6718 (Electronic)
IS  - 1748-670X (Print)
IS  - 1748-670X (Linking)
VI  - 2022
DP  - 2022
TI  - The Value of Echocardiography Combined with NT-pro BNP Level in Assessment and 
      Prognosis of Diastolic Heart Failure.
PG  - 2102496
LID - 10.1155/2022/2102496 [doi]
LID - 2102496
AB  - BACKGROUND: To investigate the significance of echocardiography combined with 
      N-terminal pro-B-type natriuretic peptide (NT-pro BNP) levels in the evaluation 
      and prognosis of diastolic heart failure (DHF). METHODS: Clinical data were 
      collected from 168 patients with DHF. Serum levels of NT-pro BNP were first 
      measured by ELISA. Meanwhile, the echocardiography was used to examine left 
      ventricular end-diastolic diameter (LVEDD), left ventricular diameter (LVD), and 
      other parameters. Multivariate logistic regression analysis was performed for 
      variables in heart failure assessment grade or poor prognosis. Finally, the 
      predictive ability for New York Heart Association (NYHA) class as well as 
      prognosis was assessed by ROC curves. RESULTS: NT-pro BNP was the overexpression 
      in the serum of patients with DHF. And the degree of elevation was related to 
      NYHA class, while NT-pro BNP levels were significantly higher in the P-MACE group 
      than in the N-MACE group. According to the multivariate logistic regression 
      analysis, the ratio of peak velocity of left atrial early diastolic blood flow to 
      early diastolic peak velocity of mitral annulus (E/Ea) and serum NT-pro BNP level 
      was risk factors for NYHA class and prognosis. However, LVEF, LVEDD, and flow 
      propagation velocity (Vp) can be a benefit condition. In addition, ROC curve 
      showed that echocardiography combined with NT-pro BNP content had higher accuracy 
      in NYHA class and prognostic assessment of DHF than applied separately. 
      CONCLUSIONS: The diagnosis of echocardiography combined with NT-pro BNP levels 
      has the potential to distinguish the NYHA class in heart function of patients 
      with DHF and determine the prognosis of patients.
CI  - Copyright (c) 2022 Shaolei Chen et al.
FAU - Chen, Shaolei
AU  - Chen S
AD  - Department of Ultrasound Medicine, Sinopharm Dongfeng General Hospital, Hubei 
      University of Medicine, Shiyan 442008, Hubei, China.
FAU - Zhou, Yanli
AU  - Zhou Y
AD  - Department of Ultrasound Medicine, Sinopharm Dongfeng General Hospital, Hubei 
      University of Medicine, Shiyan 442008, Hubei, China.
FAU - Wu, Xia
AU  - Wu X
AD  - Department of Ultrasound Medicine, Sinopharm Dongfeng General Hospital, Hubei 
      University of Medicine, Shiyan 442008, Hubei, China.
FAU - Shi, Shaojun
AU  - Shi S
AD  - Department of Ultrasound Medicine, Sinopharm Dongfeng General Hospital, Hubei 
      University of Medicine, Shiyan 442008, Hubei, China.
FAU - Wu, Haiyan
AU  - Wu H
AD  - Department of Ultrasound Medicine, Sinopharm Dongfeng General Hospital, Hubei 
      University of Medicine, Shiyan 442008, Hubei, China.
FAU - Li, Peng
AU  - Li P
AUID- ORCID: 0000-0002-3652-7870
AD  - Department of Ultrasound Medicine, Sinopharm Dongfeng General Hospital, Hubei 
      University of Medicine, Shiyan 442008, Hubei, China.
LA  - eng
PT  - Journal Article
PT  - Retracted Publication
DEP - 20220204
PL  - United States
TA  - Comput Math Methods Med
JT  - Computational and mathematical methods in medicine
JID - 101277751
RN  - 0 (Biomarkers)
RN  - 0 (Peptide Fragments)
RN  - 0 (pro-brain natriuretic peptide (1-76))
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
SB  - IM
RIN - Comput Math Methods Med. 2023 Nov 1;2023:9784095. PMID: 37946937
MH  - Aged
MH  - Biomarkers/blood
MH  - Case-Control Studies
MH  - Computational Biology
MH  - Echocardiography, Doppler, Color
MH  - Female
MH  - Heart Failure, Diastolic/*blood/classification/*diagnostic imaging
MH  - Humans
MH  - Logistic Models
MH  - Male
MH  - Middle Aged
MH  - Multivariate Analysis
MH  - Natriuretic Peptide, Brain/*blood
MH  - Peptide Fragments/*blood
MH  - Prognosis
MH  - ROC Curve
PMC - PMC8841100
COIS- The authors declare that they have no conflict of interest.
EDAT- 2022/02/17 06:00
MHDA- 2022/03/16 06:00
PMCR- 2022/02/04
CRDT- 2022/02/16 05:49
PHST- 2021/10/19 00:00 [received]
PHST- 2021/12/22 00:00 [revised]
PHST- 2022/01/04 00:00 [accepted]
PHST- 2022/02/16 05:49 [entrez]
PHST- 2022/02/17 06:00 [pubmed]
PHST- 2022/03/16 06:00 [medline]
PHST- 2022/02/04 00:00 [pmc-release]
AID - 10.1155/2022/2102496 [doi]
PST - epublish
SO  - Comput Math Methods Med. 2022 Feb 4;2022:2102496. doi: 10.1155/2022/2102496. 
      eCollection 2022.