PMID- 35176316
OWN - NLM
STAT- MEDLINE
DCOM- 20220506
LR  - 20220622
IS  - 1096-0953 (Electronic)
IS  - 0013-9351 (Linking)
VI  - 210
DP  - 2022 Jul
TI  - Ambient particulate air pollution, blood cell parameters, and effect modification 
      by psychosocial stress: Findings from two studies in three major Chinese cities.
PG  - 112932
LID - S0013-9351(22)00259-6 [pii]
LID - 10.1016/j.envres.2022.112932 [doi]
AB  - The associations between particulate matter (PM) exposure, psychosocial stress 
      and blood cell parameters are bringing novel insights to characterize the early 
      damage of multiple diseases. Based on two studies conducted in three Chinses 
      cities using cross-sectional (Beijing, 425 participants) and panel study (Tianjin 
      and Shanghai, 92 participants with 361 repeated measurements) designs, this study 
      explored the associations between short-term exposure to ambient PM and blood 
      cell parameters, and the effect modification by psychosocial stress. Increasing 
      PM(2.5) exposure was significantly associated with decreases in red blood cell 
      (RBC) count and mean corpuscular hemoglobin concentration (MCHC), and increases 
      in mean corpuscular volume (MCV), platelets count (PLT) and platelet hematocrit 
      (PCT) in both studies. For instance, a 10 mug/m(3) increment in PM(2.5) 
      concentration was associated with a 1.04% (95%CI: 0.16%, 1.92%) increase in PLT 
      (4-d) and a 1.09% (95%CI: 0.31%, 1.87%) increase in PCT (4-d) in the 
      cross-sectional study, and a 0.64% (95%CI: 0.06%, 1.22%) increase in PLT (1-d) 
      and a 0.72% (95%CI: 0.33%, 1.11%) increase in PCT (1-d) in the panel study, 
      respectively. In addition, stronger increases in MCV, PLT, and PCT associated 
      with PM(2.5) exposure were found in higher psychosocial stress group compared to 
      lower psychosocial stress group (p for interaction <0.10), indicating that blood 
      cell parameters of individuals with higher psychosocial stress might be more 
      susceptible to the early damages of PM(2.5) exposure.
CI  - Copyright (c) 2022 Elsevier Inc. All rights reserved.
FAU - Wang, Wanzhou
AU  - Wang W
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Guo, Tongjun
AU  - Guo T
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Guo, Huaqi
AU  - Guo H
AD  - School of Public Health, Shanghai Jiao Tong University School of Medicine, 
      Shanghai, China.
FAU - Chen, Xi
AU  - Chen X
AD  - Department of Occupational and Environmental Health, Tianjin Key Laboratory of 
      Environment, Nutrition and Public Health, School of Public Health, Tianjin 
      Medical University, Tianjin, China.
FAU - Ma, Yating
AU  - Ma Y
AD  - Institute of Social Psychology, School of Humanities and Social Sciences, Xi'an 
      Jiaotong University, Xi'an, Shaanxi, China.
FAU - Deng, Hongyan
AU  - Deng H
AD  - Qinglongqiao Community Health Service Center, Haidian District, Beijing, China.
FAU - Yu, Hengyi
AU  - Yu H
AD  - School of Public Health, Shanghai Jiao Tong University School of Medicine, 
      Shanghai, China.
FAU - Chen, Qiao
AU  - Chen Q
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Li, Hongyu
AU  - Li H
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Liu, Qisijing
AU  - Liu Q
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Shan, Anqi
AU  - Shan A
AD  - Department of Occupational and Environmental Health, Tianjin Key Laboratory of 
      Environment, Nutrition and Public Health, School of Public Health, Tianjin 
      Medical University, Tianjin, China.
FAU - Li, Yaoyan
AU  - Li Y
AD  - Department of Occupational and Environmental Health, Tianjin Key Laboratory of 
      Environment, Nutrition and Public Health, School of Public Health, Tianjin 
      Medical University, Tianjin, China.
FAU - Pang, Bo
AU  - Pang B
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Shi, Jiazhang
AU  - Shi J
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Wang, Xinmei
AU  - Wang X
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Chen, Juan
AU  - Chen J
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Deng, Furong
AU  - Deng F
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Sun, Zhiwei
AU  - Sun Z
AD  - Department of Toxicology and Sanitary Chemistry, School of Public Health, Capital 
      Medical University, Beijing, China; Beijing Key Laboratory of Environmental 
      Toxicology, Capital Medical University, Beijing, China.
FAU - Guo, Xinbiao
AU  - Guo X
AD  - Department of Occupational and Environmental Health Sciences, School of Public 
      Health, Peking University, Beijing, China.
FAU - Wang, Yan
AU  - Wang Y
AD  - School of Public Health, Shanghai Jiao Tong University School of Medicine, 
      Shanghai, China; The Ninth People's Hospital of Shanghai Jiao Tong University 
      School of Medicine, Shanghai, China. Electronic address: wangyan@shsmu.edu.cn.
FAU - Tang, Naijun
AU  - Tang N
AD  - Department of Occupational and Environmental Health, Tianjin Key Laboratory of 
      Environment, Nutrition and Public Health, School of Public Health, Tianjin 
      Medical University, Tianjin, China. Electronic address: tangnaijun@tmu.edu.cn.
FAU - Wu, Shaowei
AU  - Wu S
AD  - Department of Occupational and Environmental Health, School of Public Health, 
      Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, China; Key 
      Laboratory for Disease Prevention and Control and Health Promotion of Shaanxi 
      Province, Xi'an, Shaanxi, China; Key Laboratory of Trace Elements and Endemic 
      Diseases in Ministry of Health, Xi'an, Shaanxi, China. Electronic address: 
      shaowei_wu@xjtu.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20220214
PL  - Netherlands
TA  - Environ Res
JT  - Environmental research
JID - 0147621
RN  - 0 (Air Pollutants)
RN  - 0 (Dust)
RN  - 0 (Particulate Matter)
SB  - IM
MH  - *Air Pollutants/analysis/toxicity
MH  - *Air Pollution/adverse effects/analysis
MH  - Blood Cells
MH  - China
MH  - Cities
MH  - Cross-Sectional Studies
MH  - Dust
MH  - Environmental Exposure/analysis
MH  - Humans
MH  - Particulate Matter/analysis/toxicity
MH  - Stress, Psychological
OTO - NOTNLM
OT  - Biomarkers
OT  - Blood cell parameters
OT  - Effect modification
OT  - Particulate matter
OT  - Platelets
OT  - Psychosocial stress
EDAT- 2022/02/18 06:00
MHDA- 2022/05/07 06:00
CRDT- 2022/02/17 20:12
PHST- 2021/10/17 00:00 [received]
PHST- 2022/01/04 00:00 [revised]
PHST- 2022/02/07 00:00 [accepted]
PHST- 2022/02/18 06:00 [pubmed]
PHST- 2022/05/07 06:00 [medline]
PHST- 2022/02/17 20:12 [entrez]
AID - S0013-9351(22)00259-6 [pii]
AID - 10.1016/j.envres.2022.112932 [doi]
PST - ppublish
SO  - Environ Res. 2022 Jul;210:112932. doi: 10.1016/j.envres.2022.112932. Epub 2022 
      Feb 14.