PMID- 35177928 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220501 IS - 1178-7074 (Print) IS - 1178-7074 (Electronic) IS - 1178-7074 (Linking) VI - 15 DP - 2022 TI - Comprehensive Assessment of the Left Ventricular Systolic Function in the Elderly with Acute Myocardial Infarction Using Echocardiography. PG - 1437-1445 LID - 10.2147/IJGM.S348594 [doi] AB - AIM: To evaluate the left ventricular (LV) systolic function in elderly with non-ST elevation myocardial infarction (NSTEMI) and ST elevation myocardial infarction (STEMI) using real-time three-dimensional echocardiography (RT-3DE) and two-dimensional speckle tracking imaging (STI). METHODS: Forty NSTEMI and forty STEMI patients after undergoing percutaneous coronary artery intervention (PCI) were enrolled. The myocardial segments were supplied by the infarct-related artery (Myo-(IRA)) which were indicated by the selective coronary arteriography (SCA). The LV end-diastolic volume (LVEDV), end-systolic volume (LVESV), stroke volume (LVSV) and ejection fraction (LVEF) were acquired by 4D LV Volume Tom Tec. LV longitudinal peak systolic strain (LPSS), radial peak systolic strain (RPSS), circumferential peak systolic strain (CPSS) of Myo-(IRA) segments, LV rotational peak degree in the base (rot-(base)) and in the apex (rot-(apex)), and twist were acquired by strain analysis software. Forty older healthy individuals were included as normal controls. RESULTS: The LVEF of the NSTEMI and STEMI patients at 1 week after PCI were significantly lower (P<0.05), then, this parameter was improved in both groups after 3 months, but was still significantly lower than that of the controls (P<0.05). The LPSS, RPSS, CPSS of the Myo(-IRA) segments, rot(-Base), rot(-Apex) and twist in both groups were significantly lower than those in the controls. The LPSS and CPSS of the Myo-IRA segments, rot(-Base), rot(-Apex) and twist in NSTEMI patients were obviously higher than those in STEMI patients in 1 week and 3 months after PCI (P<0.05). After 3 months, the RPSS of NSTEMI patients was improved notably and was obviously higher than that of STEMI patients (P<0.05). All these values in STEMI and NSTEMI patients were improved after 3 months, apart from LPSS in STEMI patients (P>0.05), but were still significantly lower than those in the controls (P<0.05). CONCLUSION: RT-3DE and STI can sensitively assess LV systolic function with different extents of transmural damage. CI - (c) 2022 Huang et al. FAU - Huang, Xin AU - Huang X AD - Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Liu, Yuan AU - Liu Y AD - Department of Emergency, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Guan, Bo AU - Guan B AD - Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Yang, Wenyi AU - Yang W AD - Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Sun, Shasha AU - Sun S AD - Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Luo, Jiakun AU - Luo J AD - Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Luo, Yukun AU - Luo Y AD - Department of Ultrasound, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Cao, Jian AU - Cao J AD - Department of Cardiology, The Second Medical Center & National Clinical Research Center for Geriatric Diseases, Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. FAU - Deng, Yujiao AU - Deng Y AD - Department of Ultrasound, The First Medical Center of Chinese PLA General Hospital, Beijing, 100853, People's Republic of China. LA - eng PT - Journal Article DEP - 20220211 PL - New Zealand TA - Int J Gen Med JT - International journal of general medicine JID - 101515487 PMC - PMC8846626 OTO - NOTNLM OT - acute myocardial infarction OT - echocardiography OT - elderly OT - left ventricular systolic function COIS- The authors declare that they have no conflict of interests. EDAT- 2022/02/19 06:00 MHDA- 2022/02/19 06:01 PMCR- 2022/02/11 CRDT- 2022/02/18 05:46 PHST- 2021/11/17 00:00 [received] PHST- 2022/01/25 00:00 [accepted] PHST- 2022/02/18 05:46 [entrez] PHST- 2022/02/19 06:00 [pubmed] PHST- 2022/02/19 06:01 [medline] PHST- 2022/02/11 00:00 [pmc-release] AID - 348594 [pii] AID - 10.2147/IJGM.S348594 [doi] PST - epublish SO - Int J Gen Med. 2022 Feb 11;15:1437-1445. doi: 10.2147/IJGM.S348594. eCollection 2022.