PMID- 35178334
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220322
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 10
IP  - 2
DP  - 2022 Feb
TI  - Noncontact magnetically controlled capsule endoscopy for infection-free gastric 
      examination during the COVID-19 pandemic: a pilot, open-label, randomized trial.
PG  - E163-E170
LID - 10.1055/a-1648-2238 [doi]
AB  - Background and study aims  Endoscopists have been at increased risk because of 
      their direct contact with patients during the COVID-19 pandemic. For patients, 
      being diagnosed with and monitored for gastrointestinal cancer and digestive 
      diseases in timely fashion has been challenging, given pandemic-related 
      adjustments in endoscopy departments. We developed a novel noncontact 
      magnetically controlled capsule endoscopy (ncMCE) system in our medical center. 
      In the current study, we aimed to evaluate the feasibility and safety of ncMCE 
      for gastric examination. Patients and methods  Patients were randomly assigned to 
      groups that received ncMCE or MCE in a 1:1 ratio from March 26, 2020 to April 26, 
      2020. Primary endpoints were feasibility assessed by completion rate (CR) and 
      safety based on the occurrence of adverse events (AEs) including infection. 
      Secondary endpoints included maneuverability of endoscopists, pre-procedure 
      perception and post-procedure satisfaction of patients, gastric examination time 
      (GET), and diagnostic yield (DY). Results  Forty patients were enrolled with 
      100 % CR in both groups without any AEs. Neither the endoscopist nor the patients 
      were infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) 
      within 14 days after gastric examination. There were no significant differences 
      in maneuverability (19.3 vs. 20.0, P  = 0.179), pre-procedure perception (9 vs. 
      9, P  = 0.626) and post-procedure satisfaction (45 vs. 44, P =  0.999), ord DY 
      (20 % vs. 30 %, P  = 0.465). Conclusions  ncMCE is a feasible and safe method of 
      gastric examination, which has the potential to protect both medical staff and 
      patients from COVID-19 infection while providing serving as an essential 
      endoscopy service.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commercial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Zhu, Jia-Hui
AU  - Zhu JH
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Pan, Jun
AU  - Pan J
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Xu, Xiao-Nan
AU  - Xu XN
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Liu, Ya-Wei
AU  - Liu YW
AD  - Department of Gastroenterology, The First Medical Center of PLA General 
      Hospital/Chinese PLA Postgraduate Military Medical School, Beijing, China.
FAU - Qian, Yang-Yang
AU  - Qian YY
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Jiang, Xi
AU  - Jiang X
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Jiang, Bin
AU  - Jiang B
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Zhou, Wei
AU  - Zhou W
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Linghu, En-Qiang
AU  - Linghu EQ
AD  - Department of Gastroenterology, The First Medical Center of PLA General 
      Hospital/Chinese PLA Postgraduate Military Medical School, Beijing, China.
FAU - Li, Zhao-Shen
AU  - Li ZS
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
FAU - Liao, Zhuan
AU  - Liao Z
AD  - National Clinical Research Center for Digestive Diseases, Department of 
      Gastroenterology, Changhai Hospital, Shanghai, China.
LA  - eng
PT  - Journal Article
DEP - 20220215
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
EIN - Endosc Int Open. 2022 Mar 17;10(2):C2. PMID: 35308303
PMC - PMC8847063
COIS- Competing interests The authors declare that they have no conflict of interest.
EDAT- 2022/02/19 06:00
MHDA- 2022/02/19 06:01
PMCR- 2022/02/01
CRDT- 2022/02/18 05:50
PHST- 2021/03/03 00:00 [received]
PHST- 2021/08/17 00:00 [accepted]
PHST- 2022/02/18 05:50 [entrez]
PHST- 2022/02/19 06:00 [pubmed]
PHST- 2022/02/19 06:01 [medline]
PHST- 2022/02/01 00:00 [pmc-release]
AID - 10.1055/a-1648-2238 [doi]
PST - epublish
SO  - Endosc Int Open. 2022 Feb 15;10(2):E163-E170. doi: 10.1055/a-1648-2238. 
      eCollection 2022 Feb.