PMID- 35185016
OWN - NLM
STAT- MEDLINE
DCOM- 20220323
LR  - 20220323
IS  - 2052-4897 (Electronic)
IS  - 2052-4897 (Linking)
VI  - 10
IP  - 1
DP  - 2022 Feb
TI  - Mortality attributable to type 2 diabetes mellitus in Latin America and the 
      Caribbean: a comparative risk assessment analysis.
LID - 10.1136/bmjdrc-2021-002673 [doi]
LID - e002673
AB  - INTRODUCTION: We quantified the proportion and the absolute number of deaths 
      attributable to type 2 diabetes mellitus (T2DM) in Latin America and the 
      Caribbean (LAC) using an estimation approach. RESEARCH DESIGN AND METHODS: We 
      combined T2DM prevalence estimates from the NCD Risk Factor Collaboration, 
      relative risks between T2DM and all-cause mortality from a meta-analysis of 
      cohorts in LAC, and death rates from the Global Burden of Disease Study 2019. We 
      estimated population-attributable fractions (PAFs) and computed the absolute 
      number of attributable deaths in 1990 and 2019 by multiplying the PAFs by the 
      total deaths in each country, year, sex, and 5-year age group. RESULTS: Between 
      1985 and 2014 in LAC, the proportion of all-cause mortality attributable to T2DM 
      increased from 12.2% to 16.9% in men and from 14.5% to 19.3% in women. In 2019, 
      the absolute number of deaths attributable to T2DM was 349 787 in men and 330 414 
      in women. The highest death rates (deaths per 100 000 people) in 2019 were in 
      Saint Kitts and Nevis (325 in men, 229 in women), Guyana (313 in men, 272 in 
      women), and Haiti (269 in men, 265 in women). CONCLUSIONS: A substantial burden 
      of all deaths is attributed to T2DM in LAC. To decrease the mortality 
      attributable to T2DM in LAC, policies are needed to strengthen early diagnosis 
      and management, along with the prevention of complications.
CI  - (c) Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY. Published 
      by BMJ.
FAU - Guzman-Vilca, Wilmer Cristobal
AU  - Guzman-Vilca WC
AUID- ORCID: 0000-0002-2194-8496
AD  - CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano 
      Heredia, Lima, Peru.
AD  - Sociedad Cientifica de Estudiantes de Medicina Cayetano Heredia (SOCEMCH), 
      Universidad Peruana Cayetano Heredia, Lima, Peru.
FAU - Carrillo-Larco, Rodrigo M
AU  - Carrillo-Larco RM
AUID- ORCID: 0000-0002-2090-1856
AD  - CRONICAS Centre of Excellence in Chronic Diseases, Universidad Peruana Cayetano 
      Heredia, Lima, Peru rcarrill@ic.ac.uk.
AD  - Department of Epidemiology and Biostatistics, School of Public Health, Imperial 
      College London, London, UK.
AD  - Universidad Continental, Lima, Peru.
LA  - eng
GR  - WT_/Wellcome Trust/United Kingdom
GR  - 214185/Z/18/Z/WT_/Wellcome Trust/United Kingdom
PT  - Journal Article
PT  - Meta-Analysis
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - BMJ Open Diabetes Res Care
JT  - BMJ open diabetes research & care
JID - 101641391
SB  - IM
MH  - *Diabetes Mellitus, Type 2/epidemiology
MH  - Female
MH  - Humans
MH  - Latin America/epidemiology
MH  - Male
MH  - Prevalence
MH  - Risk Assessment
MH  - Risk Factors
PMC - PMC8860056
OTO - NOTNLM
OT  - population health
OT  - risk assessment
COIS- Competing interests: None declared.
EDAT- 2022/02/22 06:00
MHDA- 2022/03/24 06:00
PMCR- 2022/02/19
CRDT- 2022/02/21 05:59
PHST- 2021/11/02 00:00 [received]
PHST- 2022/01/18 00:00 [accepted]
PHST- 2022/02/21 05:59 [entrez]
PHST- 2022/02/22 06:00 [pubmed]
PHST- 2022/03/24 06:00 [medline]
PHST- 2022/02/19 00:00 [pmc-release]
AID - 10/1/e002673 [pii]
AID - bmjdrc-2021-002673 [pii]
AID - 10.1136/bmjdrc-2021-002673 [doi]
PST - ppublish
SO  - BMJ Open Diabetes Res Care. 2022 Feb;10(1):e002673. doi: 
      10.1136/bmjdrc-2021-002673.