PMID- 35188832
OWN - NLM
STAT- MEDLINE
DCOM- 20220831
LR  - 20220831
IS  - 1940-2465 (Electronic)
IS  - 1066-8969 (Linking)
VI  - 30
IP  - 7
DP  - 2022 Oct
TI  - MYC Amplification in Epithelioid Angiosarcoma of the Urinary Bladder and Prostate 
      Following Prostate Radiotherapy: A Case Report with a Novel Molecular Alteration.
PG  - 792-796
LID - 10.1177/10668969221081740 [doi]
AB  - Epithelioid angiosarcoma is a rare variant of angiosarcoma. Radiation-associated 
      epithelioid angiosarcoma of the urinary bladder and prostate is an exceedingly 
      rare tumor and there are only 8 cases of epithelioid angiosarcoma of the urinary 
      bladder and prostate associated with previous radiotherapy in the literature. To 
      the best of our knowledge, MYC gene amplification has not been previously 
      reported in epithelioid angiosarcoma of the urinary bladder and prostate 
      following radiotherapy, although it is observed in radiation-associated 
      angiosarcoma of other anatomic sites. Here we report the first case of 
      epithelioid angiosarcoma of the urinary bladder and prostate with MYC gene 
      amplification detected by fluorescence in situ hybridization (FISH) analysis in a 
      70-year-old male patient 10 years after receiving radiation and hormonal therapy 
      for prostate cancer.
FAU - Panwar, Vandana
AU  - Panwar V
AD  - 89063Department of Pathology, University of Texas Southwestern Medical Center, 
      Dallas, TX, USA.
FAU - Tintle, Suzanne J
AU  - Tintle SJ
AD  - 89063Department of Pathology, University of Texas Southwestern Medical Center, 
      Dallas, TX, USA.
FAU - Koorse Germans, Sharon
AU  - Koorse Germans S
AUID- ORCID: 0000-0001-9275-6056
AD  - 89063Department of Pathology, University of Texas Southwestern Medical Center, 
      Dallas, TX, USA.
FAU - Koduru, Prasad
AU  - Koduru P
AD  - 89063Department of Pathology, University of Texas Southwestern Medical Center, 
      Dallas, TX, USA.
FAU - Jia, Liwei
AU  - Jia L
AUID- ORCID: 0000-0002-2118-6428
AD  - 89063Department of Pathology, University of Texas Southwestern Medical Center, 
      Dallas, TX, USA.
LA  - eng
PT  - Case Reports
PT  - Journal Article
DEP - 20220221
PL  - United States
TA  - Int J Surg Pathol
JT  - International journal of surgical pathology
JID - 9314927
SB  - IM
MH  - *Hemangioendothelioma, Epithelioid/complications
MH  - *Hemangiosarcoma/etiology/genetics
MH  - Humans
MH  - In Situ Hybridization, Fluorescence
MH  - Male
MH  - Prostate/pathology
MH  - Urinary Bladder/pathology
OTO - NOTNLM
OT  - MYC amplification
OT  - angiosarcoma
OT  - prostate
OT  - urinary bladder
EDAT- 2022/02/22 06:00
MHDA- 2022/09/01 06:00
CRDT- 2022/02/21 17:09
PHST- 2022/02/22 06:00 [pubmed]
PHST- 2022/09/01 06:00 [medline]
PHST- 2022/02/21 17:09 [entrez]
AID - 10.1177/10668969221081740 [doi]
PST - ppublish
SO  - Int J Surg Pathol. 2022 Oct;30(7):792-796. doi: 10.1177/10668969221081740. Epub 
      2022 Feb 21.