PMID- 35193166 OWN - NLM STAT- MEDLINE DCOM- 20220608 LR - 20230916 IS - 2047-6310 (Electronic) IS - 2047-6302 (Print) IS - 2047-6302 (Linking) VI - 17 IP - 7 DP - 2022 Jul TI - Exploring an algorithm to harmonize International Obesity Task Force and World Health Organization child overweight and obesity prevalence rates. PG - e12905 LID - 10.1111/ijpo.12905 [doi] LID - e12905 AB - BACKGROUND: The International Obesity Task Force (IOTF) and World Health Organization (WHO) body mass index (BMI) cut-offs are widely used to assess child overweight, obesity and thinness prevalence, but the two references applied to the same children lead to different prevalence rates. OBJECTIVES: To develop an algorithm to harmonize prevalence rates based on the IOTF and WHO cut-offs, to make them comparable. METHODS: The cut-offs are defined as age-sex-specific BMI z-scores, for example, WHO +1 SD for overweight. To convert an age-sex-specific prevalence rate based on reference cut-off A to the corresponding prevalence based on reference cut-off B, first back-transform the z-score cut-offs zA and zB to age-sex-specific BMI cut-offs, then transform the BMIs to z-scores zB,A and zA,B using the opposite reference. These z-scores together define the distance between the two cut-offs as the z-score difference dzA,B = (1/2)(zB - zA + zA,B - zB,A) . Prevalence in the target group based on cut-off A is then transformed to a z-score, adjusted up or down according to dzA,B and back-transformed, and this predicts prevalence based on cut-off B. The algorithm's performance was tested on 74 groups of children from 14 European countries. RESULTS: The algorithm performed well. The standard deviation (SD) of the difference between pairs of prevalence rates was 6.6% (n = 604), while the residual SD, the difference between observed and predicted prevalence, was 2.3%, meaning that the algorithm explained 88% of the baseline variance. CONCLUSIONS: The algorithm goes some way to addressing the problem of harmonizing overweight and obesity prevalence rates for children aged 2-18. CI - (c) 2022 The Authors. Pediatric Obesity published by John Wiley & Sons Ltd on behalf of World Obesity Federation. FAU - Cole, Tim J AU - Cole TJ AUID- ORCID: 0000-0001-5711-8200 AD - Population, Policy and Practice Research and Teaching Programme, University College London Great Ormond Street Institute of Child Health, London, UK. FAU - Lobstein, Tim AU - Lobstein T AD - World Obesity Federation, London, UK. AD - Centre for Health Economics & Policy Innovation, Imperial College, London, UK. LA - eng PT - Journal Article DEP - 20220222 PL - England TA - Pediatr Obes JT - Pediatric obesity JID - 101572033 SB - IM MH - Algorithms MH - Body Mass Index MH - Child MH - Female MH - Humans MH - Male MH - *Obesity/epidemiology MH - *Overweight/epidemiology MH - Prevalence MH - World Health Organization PMC - PMC9285550 OTO - NOTNLM OT - IOTF OT - WHO OT - harmonization OT - obesity OT - overweight OT - prevalence COIS- Tim J. Cole declares the following conflicts of interest: he developed the LMS method with Peter Green and was first author on papers describing the IOTF cut-offs., , Tim Lobstein was also an author on the latter paper. EDAT- 2022/02/23 06:00 MHDA- 2022/06/09 06:00 PMCR- 2022/07/15 CRDT- 2022/02/22 20:13 PHST- 2022/01/08 00:00 [revised] PHST- 2021/07/22 00:00 [received] PHST- 2022/01/20 00:00 [accepted] PHST- 2022/02/23 06:00 [pubmed] PHST- 2022/06/09 06:00 [medline] PHST- 2022/02/22 20:13 [entrez] PHST- 2022/07/15 00:00 [pmc-release] AID - IJPO12905 [pii] AID - 10.1111/ijpo.12905 [doi] PST - ppublish SO - Pediatr Obes. 2022 Jul;17(7):e12905. doi: 10.1111/ijpo.12905. Epub 2022 Feb 22.