PMID- 35198281
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220225
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 1
DP  - 2022 Jan
TI  - The Correlation Between Surgical Procedures and Quality of Life Among Sickle Cell 
      Disease Patients: A Perspective Saudi Study.
PG  - e21367
LID - 10.7759/cureus.21367 [doi]
LID - e21367
AB  - INTRODUCTION: Sickle cell disease (SCD) is among the common prevalent diseases in 
      Saudi Arabia. It is associated with several complications that sometimes 
      necessitate surgical procedures. Those patients can also have a lower quality of 
      life (QoL) due to several reasons. Our aim in this study is to highlight the 
      association between sociodemographic data, clinical data, and SCD-related 
      surgeries in patients with their QoL. METHODS: A cross-sectional study was 
      performed using a validated Arabic version of the World Health Organization 
      QoL-BREF (WHOQOL-BREF) questionnaire distributed in electronic form. Male and 
      female Arabic speakers (18+ years old) of Saudi origin were included in this 
      study; those who did not meet these criteria were excluded. RESULTS: We 
      distributed 309 questionnaires to the targeted subjects; however, only 204 met 
      our inclusion criteria. Our findings revealed 135 female respondents and 69 male 
      respondents. Interestingly, splenectomy was not significantly associated with a 
      difference in all aspects of QoL in SCD patients. However, the data showed 
      significantly lower respective mean scores for physical health (p=0.002 & 
      p=0.022) and overall QoL (p=0.024 & p=0.042) for those who underwent 
      cholecystectomy and hip arthroplasty. In contrast, shoulder arthroplasty appeared 
      to be associated with significantly lower mean scores for physical health 
      (T=-2.597; p=0.010) and the environmental aspect of QoL (T=-2.016; p=0.045). 
      CONCLUSION: Cholecystectomy, hip arthroplasty, and shoulder arthroplasty were 
      significantly associated with lower QoL in SCD patients.
CI  - Copyright (c) 2022, Al Saad et al.
FAU - Al Saad, Ali J
AU  - Al Saad AJ
AD  - Clinical Neuroscience, King Faisal University, Al-Ahsa, SAU.
FAU - Buhalim, Rayan A
AU  - Buhalim RA
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Al Jabr, Faisal A
AU  - Al Jabr FA
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Al Dehailan, Abdulaziz M
AU  - Al Dehailan AM
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
FAU - Albahrani, Abdulaziz A
AU  - Albahrani AA
AD  - College of Medicine, King Faisal University, Al-Ahsa, SAU.
LA  - eng
PT  - Journal Article
DEP - 20220118
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC8853970
OTO - NOTNLM
OT  - heath related quality of life
OT  - kingdom of saudi arabia (ksa)
OT  - mental health and psychiatry
OT  - post cholecystectomy
OT  - post-splenectomy
OT  - psychological impacts
OT  - sickle cell anemia
OT  - surgeries
OT  - surgical operation
OT  - total joint arthroplasty
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/02/25 06:00
MHDA- 2022/02/25 06:01
PMCR- 2022/01/18
CRDT- 2022/02/24 05:42
PHST- 2022/01/17 00:00 [accepted]
PHST- 2022/02/24 05:42 [entrez]
PHST- 2022/02/25 06:00 [pubmed]
PHST- 2022/02/25 06:01 [medline]
PHST- 2022/01/18 00:00 [pmc-release]
AID - 10.7759/cureus.21367 [doi]
PST - epublish
SO  - Cureus. 2022 Jan 18;14(1):e21367. doi: 10.7759/cureus.21367. eCollection 2022 
      Jan.