PMID- 35210488
OWN - NLM
STAT- MEDLINE
DCOM- 20220307
LR  - 20220307
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 12
IP  - 1
DP  - 2022 Feb 24
TI  - Size fractionation of high-density polyethylene breakdown nanoplastics reveals 
      different toxic response in Daphnia magna.
PG  - 3109
LID - 10.1038/s41598-022-06991-1 [doi]
LID - 3109
AB  - Plastic litter is a growing environmental problem. Recently, microplastics and 
      nanoplastics, produced during breakdown processes in nature, have been in focus. 
      Although there is a growing knowledge concerning microplastic, little is still 
      known about the effect of nanoplastics. We have showed that mechanical breakdown 
      of high-density polyethylene (HDPE), followed by filtration through 0.8 microm 
      filters, produces material toxic to the freshwater zooplankton Daphnia magna and 
      affected the reproduction in life-time tests. However, further size fractionation 
      and purification reveals that the nanoplastics fraction is non-toxic at these 
      concentrations, whereas the fraction with smaller sizes, below ~ 3 nm, is toxic. 
      The HDPE nanoplastics are highly oxidized and with an average diameter of 110 nm. 
      We conclude that mechanical breakdown of HDPE may cause environmental problems, 
      but that the fraction of leached additives and short chain HDPE are more 
      problematic than HDPE nanoplastics.
CI  - (c) 2022. The Author(s).
FAU - Ekvall, Mikael T
AU  - Ekvall MT
AD  - Aquatic Ecology Unit, Department of Biology, Ecology Building, Lund University, 
      223 62, Lund, Sweden.
AD  - NanoLund, Lund University, Box 118, 221 00, Lund, Sweden.
FAU - Gimskog, Isabella
AU  - Gimskog I
AD  - NanoLund, Lund University, Box 118, 221 00, Lund, Sweden.
AD  - Biochemistry and Structural Biology, Lund University, Box 124, 221 00, Lund, 
      Sweden.
FAU - Hua, Jing
AU  - Hua J
AD  - NanoLund, Lund University, Box 118, 221 00, Lund, Sweden.
AD  - Biochemistry and Structural Biology, Lund University, Box 124, 221 00, Lund, 
      Sweden.
FAU - Kelpsiene, Egle
AU  - Kelpsiene E
AD  - NanoLund, Lund University, Box 118, 221 00, Lund, Sweden.
AD  - Biochemistry and Structural Biology, Lund University, Box 124, 221 00, Lund, 
      Sweden.
FAU - Lundqvist, Martin
AU  - Lundqvist M
AD  - NanoLund, Lund University, Box 118, 221 00, Lund, Sweden.
AD  - Biochemistry and Structural Biology, Lund University, Box 124, 221 00, Lund, 
      Sweden.
FAU - Cedervall, Tommy
AU  - Cedervall T
AD  - NanoLund, Lund University, Box 118, 221 00, Lund, Sweden. 
      tommy.cedervall@biochemistry.lu.se.
AD  - Biochemistry and Structural Biology, Lund University, Box 124, 221 00, Lund, 
      Sweden. tommy.cedervall@biochemistry.lu.se.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220224
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
RN  - 0 (Microplastics)
RN  - 0 (Plastics)
RN  - 0 (Water Pollutants, Chemical)
RN  - 9002-88-4 (Polyethylene)
SB  - IM
MH  - Animals
MH  - Chemical Fractionation
MH  - Daphnia/*drug effects/metabolism/*physiology
MH  - Fresh Water
MH  - Microplastics/toxicity
MH  - Plastics/toxicity
MH  - Polyethylene/*toxicity
MH  - Water Pollutants, Chemical/toxicity
MH  - Zooplankton/drug effects
PMC - PMC8873248
COIS- The authors declare no competing interests.
EDAT- 2022/02/26 06:00
MHDA- 2022/03/08 06:00
PMCR- 2022/02/24
CRDT- 2022/02/25 05:34
PHST- 2021/10/08 00:00 [received]
PHST- 2022/02/10 00:00 [accepted]
PHST- 2022/02/25 05:34 [entrez]
PHST- 2022/02/26 06:00 [pubmed]
PHST- 2022/03/08 06:00 [medline]
PHST- 2022/02/24 00:00 [pmc-release]
AID - 10.1038/s41598-022-06991-1 [pii]
AID - 6991 [pii]
AID - 10.1038/s41598-022-06991-1 [doi]
PST - epublish
SO  - Sci Rep. 2022 Feb 24;12(1):3109. doi: 10.1038/s41598-022-06991-1.