PMID- 35228493 OWN - NLM STAT- MEDLINE DCOM- 20220302 LR - 20231213 IS - 1881-7742 (Electronic) IS - 0301-4800 (Linking) VI - 68 IP - 1 DP - 2022 TI - Effectiveness of Textured Soybean Protein on Blood Biochemistry in Vietnamese Type 2 Diabetes Mellitus Patients. PG - 32-38 LID - 10.3177/jnsv.68.32 [doi] AB - Type 2 diabetes mellitus (T2DM) has been increasing rapidly in Vietnam as well as world-wide. One of the major causes of the condition is low fiber intake. It is difficult to eat large amounts of vegetables every day to reach a sufficient amount of fiber but Textured Soybean Protein is rich in fiber. The study aimed to examine the effectiveness of Textured Soybean Protein consumption on T2DM patients. In this randomized controlled trial, 47 T2DM patients were divided into an intervention group (n=24) and a control group (n=23). The intervention group were asked to consume 40 g Textured Soybean Protein in 2 dishes for 4 wk. The control group continued their usual diet. Fasting blood samples were drawn before and after intervention to measure fasting plasma glucose (FPG), fructosamine, low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), total cholesterol (T-C), and triglycerides (TG). A 3-day food record was conducted at 1 wk before (baseline) and at the last week (final) of the intervention period. In the Textured Soybean Protein consumption group, there was a significant decrease in fructosamine (363+/-86 mumol/L to 347+/-82 mumol/L, p=0.03), T-C (5.2+/-0.9 mmol/L to 4.8+/-0.8 mmol/L, p=0.02) and TG (3.5+/-2.2 mmol/L to 2.8+/-2.0 mmol/L, p=0.02). Total energy intake in the two groups did not change significantly. There was a shift in the dietary pattern of the Textured Soybean Protein consumption group; lipid intake showed a significant decrease (p=0.001) and fiber intake increased by 6 g (p<0.001). The consumption of Textured Soybean Protein in the diet could have favorable effects in improving glycemic and lipid concentrations in T2DM patients. FAU - Ta, Ngoc Thi AU - Ta NT AD - Department of International Nutrition, Jumonji University Graduate School of Human Life Sciences. FAU - Ngo, Hien Thi Thu AU - Ngo HTT AD - Department of International Nutrition, Jumonji University Graduate School of Human Life Sciences. FAU - Nguyen, Phuong Mai AU - Nguyen PM AD - Department of International Nutrition, Jumonji University Graduate School of Human Life Sciences. FAU - Truong, Thu Thi AU - Truong TT AD - Department of Food and Nutrition, Hai Duong Medical Technical University. FAU - Nguyen, Giang Huong AU - Nguyen GH AD - Department of International Nutrition, Jumonji University Graduate School of Human Life Sciences. FAU - Dinh, Hang Thi Dieu AU - Dinh HTD AD - Hai Duong Medical Technical University. FAU - Nguyen, Linh Thuy AU - Nguyen LT AD - Department of Nutrition, Hanoi Medical University Hospital. FAU - LE, Huong Thi AU - LE HT AD - Department of Nutrition, Hanoi Medical University Hospital. FAU - Nguyen, Khan Cong AU - Nguyen KC AD - Hai Duong Medical Technical University. FAU - Yamamoto, Shigeru AU - Yamamoto S AD - Department of International Nutrition, Jumonji University Graduate School of Human Life Sciences. LA - eng PT - Journal Article PT - Randomized Controlled Trial PL - Japan TA - J Nutr Sci Vitaminol (Tokyo) JT - Journal of nutritional science and vitaminology JID - 0402640 RN - 0 (Blood Glucose) RN - 0 (Cholesterol, HDL) RN - 0 (Soybean Proteins) RN - 0 (Triglycerides) SB - IM MH - Asian People MH - Blood Glucose/metabolism MH - Cholesterol, HDL MH - *Diabetes Mellitus, Type 2 MH - Humans MH - *Soybean Proteins MH - Glycine max MH - Triglycerides OTO - NOTNLM OT - Textured Soybean Protein OT - fiber OT - hyperlipidemia OT - soybean OT - soybean protein OT - type 2 diabetes EDAT- 2022/03/02 06:00 MHDA- 2022/03/03 06:00 CRDT- 2022/03/01 05:55 PHST- 2022/03/01 05:55 [entrez] PHST- 2022/03/02 06:00 [pubmed] PHST- 2022/03/03 06:00 [medline] AID - 10.3177/jnsv.68.32 [doi] PST - ppublish SO - J Nutr Sci Vitaminol (Tokyo). 2022;68(1):32-38. doi: 10.3177/jnsv.68.32.