PMID- 35228890
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220302
IS  - 2051-3380 (Print)
IS  - 2051-3380 (Electronic)
IS  - 2051-3380 (Linking)
VI  - 10
IP  - 3
DP  - 2022 Mar
TI  - Nontuberculous Mycobacterium-associated immune reconstitution inflammatory 
      syndrome in a non-HIV immunosuppressed patient.
PG  - e0918
LID - 10.1002/rcr2.918 [doi]
LID - e0918
AB  - A 69-year-old woman with rheumatoid arthritis, using immunosuppressants, 
      including etanercept-a tumour necrosis factor (TNF)-alpha antagonist-was referred to 
      our hospital with fever and fatigue. Chest computed tomography revealed cavities 
      in the left upper lobe. As Mycobacterium intracellulare infection was diagnosed, 
      all immunosuppressants were discontinued, and treatment with anti-nontuberculous 
      Mycobacterium drugs was initiated. However, her condition worsened paradoxically. 
      We diagnosed immune reconstitution inflammatory syndrome (IRIS) resulting from 
      the discontinuation of the TNF-alpha antagonist. Her condition improved with 
      prednisolone treatment. IRIS is generally observed during HIV treatment, but a 
      good understanding of immunosuppressant-related non-HIV IRIS is needed.
CI  - (c) 2022 The Authors. Respirology Case Reports published by John Wiley & Sons 
      Australia, Ltd on behalf of The Asian Pacific Society of Respirology.
FAU - Kobayashi, Misato
AU  - Kobayashi M
AUID- ORCID: 0000-0001-6042-9819
AD  - Department of Internal Medicine, Division of Medical Oncology and Respiratory 
      Medicine Shimane University Faculty of Medicine Izumo Japan.
FAU - Tsubata, Yukari
AU  - Tsubata Y
AUID- ORCID: 0000-0002-4260-2849
AD  - Department of Internal Medicine, Division of Medical Oncology and Respiratory 
      Medicine Shimane University Faculty of Medicine Izumo Japan.
FAU - Shiratsuki, Yohei
AU  - Shiratsuki Y
AD  - Department of Internal Medicine, Division of Medical Oncology and Respiratory 
      Medicine Shimane University Faculty of Medicine Izumo Japan.
FAU - Hotta, Takamasa
AU  - Hotta T
AD  - Department of Internal Medicine, Division of Medical Oncology and Respiratory 
      Medicine Shimane University Faculty of Medicine Izumo Japan.
FAU - Hamaguchi, Megumi
AU  - Hamaguchi M
AUID- ORCID: 0000-0002-1995-9217
AD  - Department of Internal Medicine, Division of Medical Oncology and Respiratory 
      Medicine Shimane University Faculty of Medicine Izumo Japan.
FAU - Isobe, Takeshi
AU  - Isobe T
AD  - Department of Internal Medicine, Division of Medical Oncology and Respiratory 
      Medicine Shimane University Faculty of Medicine Izumo Japan.
LA  - eng
PT  - Case Reports
DEP - 20220222
PL  - United States
TA  - Respirol Case Rep
JT  - Respirology case reports
JID - 101631052
PMC - PMC8864326
OTO - NOTNLM
OT  - immune reconstitution inflammatory syndrome
OT  - nontuberculous Mycobacterium
OT  - paradoxical reactions
OT  - tumour necrosis factor-alpha antagonists
COIS- None declared.
EDAT- 2022/03/02 06:00
MHDA- 2022/03/02 06:01
PMCR- 2022/02/22
CRDT- 2022/03/01 05:57
PHST- 2022/01/10 00:00 [received]
PHST- 2022/02/05 00:00 [revised]
PHST- 2022/02/14 00:00 [accepted]
PHST- 2022/03/01 05:57 [entrez]
PHST- 2022/03/02 06:00 [pubmed]
PHST- 2022/03/02 06:01 [medline]
PHST- 2022/02/22 00:00 [pmc-release]
AID - RCR2918 [pii]
AID - 10.1002/rcr2.918 [doi]
PST - epublish
SO  - Respirol Case Rep. 2022 Feb 22;10(3):e0918. doi: 10.1002/rcr2.918. eCollection 
      2022 Mar.