PMID- 35236188
OWN - NLM
STAT- MEDLINE
DCOM- 20230414
LR  - 20230414
IS  - 1477-111X (Electronic)
IS  - 0267-6591 (Linking)
VI  - 38
IP  - 4
DP  - 2023 May
TI  - A six-year study of complications related to peripherally inserted central 
      catheters: A multi-center retrospective cohort study in China.
PG  - 689-697
LID - 10.1177/02676591221076287 [doi]
AB  - OBJECTIVE: Peripherally inserted central catheters (PICCs), the most frequent 
      central venous catheter, are used to provide medical treatments, although 
      long-term PICC-related adverse outcomes are unknown in China. This study 
      systematically investigated PICC-related complications in four Chinese hospitals. 
      METHODS: Between January 2014 and January 2020, we analyzed the results of 3550 
      patients with PICC who were referred to four Chinese hospitals. All patients 
      underwent PICC treatment in four Chinese hospitals. Patient-reported signs and 
      symptoms of a putative PICC-related complication or functional were studied. 
      Long-term outcomes and hospitalization costs were also evaluated. RESULTS: An 
      aggregate of 3285 patients were enrolled in the analytic cohort. 58.6% were 
      females and 41.4% were males. The most common reasons for PICC placement included 
      oncologic malignancy and critically ill patients. The majority of PICCs had 
      valved systems (90.7%) and were implanted in the right side (85.5%) and into the 
      basilic vein (87.7%). At least one potential PICC-related problem or adverse 
      effects (AEs) was reported by 67.3% of patients. Central line-associated 
      bloodstream infection (28.1%) and symptomatic deep vein thrombosis (20.7%) were 
      the most common complications. The majority of PICCs were removed for causes 
      other than AEs, with just 723 reported AEs accounting for 22.0% of all PICC 
      removals. The most reasons for PICCs removal were occlusion (425, 12.9%) and 
      exit-site infections (189, 5.8%). CONCLUSIONS: This study is the first 
      retrospective study in our country to explore PICC-related complications. While 
      living with a PICC, more than 67.3% of patients report signs and symptoms of at 
      least one PICC-related problem or adverse impacts, such as difficulties with PICC 
      use and poor effects on physical and social function. In this group, PICCs are 
      safe and effective, although the danger of PICC-related problems should not be 
      disregarded.
FAU - Wan, Rong
AU  - Wan R
AD  - Department of Nursing, The 904th Hospital of Joint Logistic Support Force, Wuxi, 
      China.
FAU - Gu, Lilei
AU  - Gu L
AD  - Department of Oncology, The 904th Hospital of Joint Logistic Support Force, Wuxi, 
      China.
FAU - Yin, Bi
AU  - Yin B
AD  - Department of Physical Examination, The 904th Hospital of Joint Logistic Support 
      Force, Wuxi, China.
FAU - Cai, Shengwei
AU  - Cai S
AD  - Department of Oncology, The 904th Hospital of Joint Logistic Support Force, Wuxi, 
      China.
FAU - Zhou, Rengui
AU  - Zhou R
AD  - Department of Oncology, The 904th Hospital of Joint Logistic Support Force, Wuxi, 
      China.
FAU - Yang, Weilin
AU  - Yang W
AUID- ORCID: 0000-0001-5623-3258
AD  - Department of Oncology, The 904th Hospital of Joint Logistic Support Force, Wuxi, 
      China.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20220302
PL  - England
TA  - Perfusion
JT  - Perfusion
JID - 8700166
SB  - IM
MH  - Male
MH  - Female
MH  - Humans
MH  - Retrospective Studies
MH  - *Catheterization, Central Venous/adverse effects
MH  - Risk Factors
MH  - *Central Venous Catheters/adverse effects
MH  - Catheters
MH  - *Catheterization, Peripheral/adverse effects
OTO - NOTNLM
OT  - China
OT  - Complications
OT  - central line-associated bloodstream infection
OT  - deep vein thrombosis
OT  - peripherally inserted central catheters
EDAT- 2022/03/04 06:00
MHDA- 2023/04/14 06:42
CRDT- 2022/03/03 05:30
PHST- 2023/04/14 06:42 [medline]
PHST- 2022/03/04 06:00 [pubmed]
PHST- 2022/03/03 05:30 [entrez]
AID - 10.1177/02676591221076287 [doi]
PST - ppublish
SO  - Perfusion. 2023 May;38(4):689-697. doi: 10.1177/02676591221076287. Epub 2022 Mar 
      2.