PMID- 35236419
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220310
IS  - 2055-5784 (Print)
IS  - 2055-5784 (Electronic)
IS  - 2055-5784 (Linking)
VI  - 8
IP  - 1
DP  - 2022 Mar 2
TI  - Development and feasibility testing of a physical activity intervention for youth 
      with anxiety and depression: a study protocol.
PG  - 48
LID - 10.1186/s40814-022-01010-6 [doi]
LID - 48
AB  - BACKGROUND: Anxiety and depressive disorders in children and adolescents are 
      highly prevalent and account for more than half of all youth psychiatric 
      disorders. Left untreated, anxiety, and depression lead to numerous detrimental 
      outcomes, including reduced quality of life, psychiatric, and somatic comorbidity 
      and even reduced lifespan. This puts a large strain on child and adolescent 
      mental healthcare services (CAMHS) to provide effective treatments. However, even 
      when provided the best evidence-based treatment, between 40-50% of patients 
      continue to report significant symptom burdens. Thus, there is an immediate need 
      for supplemental and/or new treatment approaches. Physical activity as a 
      supplementary treatment may be such an approach. However, research investigating 
      this approach within this population is scant. This protocol paper describes the 
      development and feasibility trial of a physical activity-based intervention 
      targeting anxiety and depressive symptoms in youth treated in CAMHS. 
      METHODS/DESIGN: The study is based on the UK Medical Council Research Framework 
      (MRC) for developing and evaluating complex interventions. Feasibility and 
      acceptability of the physical activity intervention (confident, active, and happy 
      youth) will be evaluated in an uncontrolled open-label trial using qualitative 
      and quantitative data. Twenty youths with anxiety and/or depressive symptoms will 
      be recruited. Acceptability of assessment procedures, the intervention, and 
      perceived benefits and barriers to participation will be assessed, and 
      qualitative interviews with participants, caregivers, and referring specialists 
      will explore contextual and practical factors associated with intervention 
      delivery. Physical activity will be measured using the Actigraph GT3X+ monitor at 
      baseline, and post-intervention and change in anxiety and depression will be 
      assessed. DISCUSSION: This study will contribute to the development of 
      supplementary physical treatment interventions for youth with anxiety and 
      depression in contact with CAMHS. The goal is to examine new avenues of treatment 
      that ultimately may improve upon current treatment outcomes of anxiety and 
      depression. This work will be in preparation for a future definitive randomized 
      controlled trial (RCT) of this approach, in line with the MRC Framework. TRIAL 
      REGISTRATION: ClnicalTrials.gov, NCT05049759 . Registered on August 19, 2021. 
      Retrospectively registered.
CI  - (c) 2022. The Author(s).
FAU - Kodal, Arne
AU  - Kodal A
AD  - Department of Child and Adolescent Psychiatry, Division of Psychiatry, Haukeland 
      University Hospital, p.b 1400, N-5021, Bergen, Norway. 
      Arne.kodal@helse-bergen.no.
FAU - Muirhead, Fiona
AU  - Muirhead F
AD  - School of Psychological Science and Health, University of Strathclyde, Glasgow, 
      Scotland.
FAU - Reilly, John J
AU  - Reilly JJ
AD  - School of Psychological Science and Health, University of Strathclyde, Glasgow, 
      Scotland.
FAU - Wergeland, Gro Janne H
AU  - Wergeland GJH
AD  - Department of Child and Adolescent Psychiatry, Division of Psychiatry, Haukeland 
      University Hospital, p.b 1400, N-5021, Bergen, Norway.
AD  - Department of Clinical Medicine, Faculty of Medicine, University of Bergen, 
      N-5020, Bergen, Norway.
FAU - Thorsen, Paul Joachim Bloch
AU  - Thorsen PJB
AD  - Department of Child and Adolescent Psychiatry, Division of Psychiatry, Haukeland 
      University Hospital, p.b 1400, N-5021, Bergen, Norway.
FAU - Bovim, Lars Peder
AU  - Bovim LP
AD  - Department of Health and Functioning, Western Norway University of Applied 
      Sciences, Bergen, Norway.
FAU - Elgen, Irene Bircow
AU  - Elgen IB
AD  - Department of Child and Adolescent Psychiatry, Division of Psychiatry, Haukeland 
      University Hospital, p.b 1400, N-5021, Bergen, Norway.
AD  - Department of Clinical Medicine, Faculty of Medicine, University of Bergen, 
      N-5020, Bergen, Norway.
LA  - eng
SI  - ClinicalTrials.gov/NCT05049759
PT  - Journal Article
DEP - 20220302
PL  - England
TA  - Pilot Feasibility Stud
JT  - Pilot and feasibility studies
JID - 101676536
PMC - PMC8889653
OTO - NOTNLM
OT  - Anxiety
OT  - Depression
OT  - Intervention
OT  - Physical activity
OT  - Youth
COIS- The authors declare that they have no competing interests.
EDAT- 2022/03/04 06:00
MHDA- 2022/03/04 06:01
PMCR- 2022/03/02
CRDT- 2022/03/03 05:31
PHST- 2021/09/28 00:00 [received]
PHST- 2022/02/18 00:00 [accepted]
PHST- 2022/03/03 05:31 [entrez]
PHST- 2022/03/04 06:00 [pubmed]
PHST- 2022/03/04 06:01 [medline]
PHST- 2022/03/02 00:00 [pmc-release]
AID - 10.1186/s40814-022-01010-6 [pii]
AID - 1010 [pii]
AID - 10.1186/s40814-022-01010-6 [doi]
PST - epublish
SO  - Pilot Feasibility Stud. 2022 Mar 2;8(1):48. doi: 10.1186/s40814-022-01010-6.