PMID- 35239782
OWN - NLM
STAT- MEDLINE
DCOM- 20220307
LR  - 20220319
IS  - 1414-431X (Electronic)
IS  - 0100-879X (Print)
IS  - 0100-879X (Linking)
VI  - 55
DP  - 2022
TI  - Strenuous swimming raises blood non-enzymatic antioxidant capacity in rats.
PG  - e11891
LID - S0100-879X2022000100621 [pii]
LID - 10.1590/1414-431X2022e11891 [doi]
LID - e11891
AB  - The non-enzymatic antioxidant system protects blood components from oxidative 
      damage and/or injury. Herein, plasma non-enzymatic antioxidant capacity after 
      acute strenuous swimming exercise (Exe) and exercise until exhaustion (Exh) was 
      measured in rats. The experiments were carried out in never exposed (Nex) and 
      pre-exposed (Pex) groups. The Nex group did not undergo any previous training 
      before the acute strenuous swimming test and the Pex group was submitted to daily 
      swimming for 10 min in the first week and 15 min per day in the second week 
      before testing. Plasma glucose, lactate, and pyruvate were measured and plasma 
      total protein sulfhydryl groups (thiol), trolox equivalent antioxidant capacity 
      (TEAC), ferric reducing ability of plasma (FRAP), and total radical-trapping 
      antioxidant parameter (TRAP) levels were evaluated. There were marked increases 
      in plasma lactate concentrations (Nex-Control 1.31+/-0.20 vs NexExe 4.16+/-0.39 vs 
      NexExh 7.19+/-0.67) and in thiol (Nex-Control 271.9+/-5.6 vs NexExh 314.7+/-5.7), TEAC 
      (Nex-Control 786.4+/-60.2 vs NexExh 1027.7+/-58.2), FRAP (Nex-Control 309.2+/-17.7 vs 
      NexExh 413.4+/-24.3), and TRAP (Nex-Control 0.50+/-0.15 vs NexExh 2.6+/-0.32) levels 
      after acute swimming and/or exhaustion. Also, there were increased plasma lactate 
      concentrations (Pex-Control 1.39+/-0.15 vs PexExe 5.22+/-0.91 vs PexExh 10.07+/-0.49), 
      thiol (Pex-Control 252.9+/-8.2 vs PexExh 284.6+/-6.7), FRAP (Pex-Control 296.5+/-15.4 
      vs PexExh 445.7+/-45.6), and TRAP (Pex-Control 1.8+/-0.1 vs PexExh 4.6+/-0.2) levels 
      after acute swimming and/or exhaustion. Lactate showed the highest percent of 
      elevation in the Nex and Pex groups. In conclusion, plasma lactate may contribute 
      to plasma antioxidant defenses, and the TRAP assay is the most sensitive assay 
      for assessing plasma non-antioxidant capacity after strenuous exercise.
FAU - Godoy, G
AU  - Godoy G
AUID- ORCID: 0000-0003-3339-0853
AD  - Programa de Pos-Graduacao em Ciencias Farmaceuticas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
FAU - Travassos, P B
AU  - Travassos PB
AUID- ORCID: 0000-0001-6914-2494
AD  - Programa de Pos-Graduacao em Ciencias Biologicas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
FAU - Antunes, M M
AU  - Antunes MM
AUID- ORCID: 0000-0003-4728-8518
AD  - Programa de Pos-Graduacao em Ciencias Farmaceuticas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
FAU - Iwanaga, C C
AU  - Iwanaga CC
AUID- ORCID: 0000-0002-8261-6380
AD  - Programa de Pos-Graduacao em Ciencias Farmaceuticas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
FAU - Sa-Nakanishi, A B
AU  - Sa-Nakanishi AB
AUID- ORCID: 0000-0002-2300-1861
AD  - Programa de Pos-Graduacao em Ciencias Biologicas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
FAU - Curi, R
AU  - Curi R
AUID- ORCID: 0000-0001-5095-9154
AD  - Programa de Pos-Graduacao Interdisciplinar em Ciencias da Saude, Universidade 
      Cruzeiro do Sul, Sao Paulo, SP, Brasil.
AD  - Secao de Producao de Imunobiologicos, Centro Bioindustrial, Instituto Butantan, 
      Sao Paulo, SP, Brasil.
FAU - Comar, J F
AU  - Comar JF
AUID- ORCID: 0000-0002-9518-7589
AD  - Programa de Pos-Graduacao em Ciencias Biologicas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
FAU - Bazotte, R B
AU  - Bazotte RB
AUID- ORCID: 0000-0001-8563-7913
AD  - Programa de Pos-Graduacao em Ciencias Farmaceuticas, Universidade Estadual de 
      Maringa, Maringa, PR, Brasil.
LA  - eng
PT  - Journal Article
DEP - 20220228
PL  - Brazil
TA  - Braz J Med Biol Res
JT  - Brazilian journal of medical and biological research = Revista brasileira de 
      pesquisas medicas e biologicas
JID - 8112917
RN  - 0 (Antioxidants)
RN  - 8558G7RUTR (Pyruvic Acid)
SB  - IM
MH  - Animals
MH  - *Antioxidants/metabolism
MH  - Oxidative Stress
MH  - *Physical Conditioning, Animal
MH  - Pyruvic Acid
MH  - Rats
MH  - Swimming
PMC - PMC8905668
EDAT- 2022/03/04 06:00
MHDA- 2022/03/08 06:00
PMCR- 2022/02/28
CRDT- 2022/03/03 17:14
PHST- 2021/10/23 00:00 [received]
PHST- 2022/01/04 00:00 [accepted]
PHST- 2022/03/03 17:14 [entrez]
PHST- 2022/03/04 06:00 [pubmed]
PHST- 2022/03/08 06:00 [medline]
PHST- 2022/02/28 00:00 [pmc-release]
AID - S0100-879X2022000100621 [pii]
AID - 10.1590/1414-431X2022e11891 [doi]
PST - epublish
SO  - Braz J Med Biol Res. 2022 Feb 28;55:e11891. doi: 10.1590/1414-431X2022e11891. 
      eCollection 2022.