PMID- 35242378
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220502
IS  - 2072-1439 (Print)
IS  - 2077-6624 (Electronic)
IS  - 2072-1439 (Linking)
VI  - 14
IP  - 1
DP  - 2022 Jan
TI  - Transthoracic minimally invasive closure for the treatment of ruptured sinus of 
      Valsalva aneurysm: immediate and mid-term follow-up results.
PG  - 169-176
LID - 10.21037/jtd-22-32 [doi]
AB  - BACKGROUND: We aimed to evaluate the immediate and mid-term outcomes of 
      transthoracic minimally invasive closure (TMIC) of ruptured sinus of Valsalva 
      aneurysm (RSVA), which is a rare and mostly congenital heart disease. METHODS: 
      From January 2014 to November 2020, 19 patients (16 males, 3 females) with RSVA 
      were selected for TMIC and were followed up at our centre. Data were analysed 
      from our prospectively collected database and clinical mid-term follow-up was 
      obtained. RESULTS: Among these 19 cases, transthoracic echocardiography showed 
      rupture of the right coronary sinus to the right atrium in 9 patients, 
      non-coronary sinus rupture to the right atrium in 7 patients, and right coronary 
      sinus rupture to the right ventricle in 3 patients. Most (13/19) cases were New 
      York Heart Association (NYHA) functional class III or IV. The mean diameters of 
      the defect from the aortic end and ruptured site were 8.8+/-3.0 and 6.4+/-2.6 mm, 
      respectively. TMIC was attempted using ventricular septal defect (VSD)/patent 
      ductus arteriosus (PDA) occluders 2-7 mm larger than the aortic ends of the 
      defects. All patients were successfully treated by TMIC and achieved complete 
      closure at discharge after a mean hospital stay length of 6.2+/-2.5 days. Seventeen 
      patients were NYHA class I while 2 patients were NYHA class II. No cases of 
      residual shunts, device embolization, infective endocarditis, or aortic 
      regurgitation were observed during a median follow-up of 36 months (range, 16-84 
      months). CONCLUSIONS: In appropriately selected cases with RSVA, TMIC is an 
      attractive alternative to surgery, with a high technical success rate and 
      encouraging short-term and mid-term outcomes. However, long-term follow-up is 
      needed.
CI  - 2022 Journal of Thoracic Disease. All rights reserved.
FAU - Wang, Shixiong
AU  - Wang S
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Liu, Debin
AU  - Liu D
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Li, Yongnan
AU  - Li Y
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Wu, Shiqun
AU  - Wu S
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Wang, Weifan
AU  - Wang W
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Ma, Qi
AU  - Ma Q
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Li, Yunjiao
AU  - Li Y
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Wang, Wenli
AU  - Wang W
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
FAU - Gao, Bingren
AU  - Gao B
AD  - Department of Cardiac Surgery, Lanzhou University Second Hospital, Lanzhou, 
      China.
LA  - eng
PT  - Journal Article
PL  - China
TA  - J Thorac Dis
JT  - Journal of thoracic disease
JID - 101533916
PMC - PMC8828512
OTO - NOTNLM
OT  - Ruptured sinus of Valsalva aneurysm (RSVA)
OT  - closure
OT  - congenital heart disease
OT  - minimally invasive
OT  - transesophageal echocardiography (TEE)
COIS- Conflicts of Interest: All authors have completed the ICMJE uniform disclosure 
      form (available at 
      https://jtd.amegroups.com/article/view/10.21037/jtd-22-32/coif). The authors have 
      no conflicts of interest to declare.
EDAT- 2022/03/05 06:00
MHDA- 2022/03/05 06:01
PMCR- 2022/01/01
CRDT- 2022/03/04 05:40
PHST- 2021/11/30 00:00 [received]
PHST- 2022/01/17 00:00 [accepted]
PHST- 2022/03/04 05:40 [entrez]
PHST- 2022/03/05 06:00 [pubmed]
PHST- 2022/03/05 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - jtd-14-01-169 [pii]
AID - 10.21037/jtd-22-32 [doi]
PST - ppublish
SO  - J Thorac Dis. 2022 Jan;14(1):169-176. doi: 10.21037/jtd-22-32.