PMID- 35248813
OWN - NLM
STAT- MEDLINE
DCOM- 20220331
LR  - 20220401
IS  - 1873-3379 (Electronic)
IS  - 0891-4222 (Linking)
VI  - 124
DP  - 2022 May
TI  - Estimation of the minimal clinically important difference on the Aberrant 
      Behaviour Checklist-Irritability (ABC-I) for people with intellectual 
      disabilities who display aggressive challenging behaviour: A triangulated 
      approach.
PG  - 104202
LID - S0891-4222(22)00032-4 [pii]
LID - 10.1016/j.ridd.2022.104202 [doi]
AB  - BACKGROUND: The minimal clinically important difference (MCID) is relevant in the 
      estimation of improvement in a patient outcome. AIM: To determine the MCID on the 
      Aberrant Behaviour Checklist-Irritability (ABC-I), widely used to measure the 
      effects of intervention for aggressive challenging behaviour in people with 
      intellectual disabilities. METHOD AND PROCEDURES: We utilised distribution and 
      anchor based methods to estimate the ABC-I MCID. We extracted data from 15 
      randomised controlled trials (RCTs) for meta-analysis. We conducted three online 
      workshops with family carers and professionals to consider meaningful change in 
      case vignettes of increasing severity of aggressive challenging behaviour. 
      OUTCOMES AND RESULTS: We did not find overlap in the range of values between the 
      two approaches. The meta-analysis indicated a range of MCID on the ABC-I (0.05, 
      4.94) whilst the anchor-based estimation indicated a larger change (6.6, 16.6). 
      CONCLUSIONS AND IMPLICATIONS: The MCID is essential in interpreting the results 
      from intervention studies. The present work was undertaken as part of a wider 
      programme on the development and testing of a psychosocial intervention for 
      aggressive challenging behaviour, and it is of interest to researchers in 
      justifying how they choose and determine the MCID on the outcome of interest.
CI  - Copyright (c) 2022 Elsevier Ltd. All rights reserved.
FAU - Hassiotis, Angela
AU  - Hassiotis A
AD  - UCL Division of Psychiatry and Camden Learning Disability Service, London, UK. 
      Electronic address: a.hassiotis@ucl.ac.uk.
FAU - Melville, Craig
AU  - Melville C
AD  - Psychological Medicine, University of Glasgow, UK.
FAU - Jahoda, Andrew
AU  - Jahoda A
AD  - Psychological Medicine, University of Glasgow, UK.
FAU - Strydom, Andre
AU  - Strydom A
AD  - Institute of Psychiatry, Psychology and Neurosciences, Kings College London, UK.
FAU - Cooper, Sally-Ann
AU  - Cooper SA
AD  - Psychological Medicine, University of Glasgow, UK.
FAU - Taggart, Laurence
AU  - Taggart L
AD  - Institute of Nursing and Health Research, Ulster University, Belfast, UK.
FAU - Cooper, Vivien
AU  - Cooper V
AD  - Challenging Behaviour Foundation, UK.
FAU - Steed, Elizabeth
AU  - Steed E
AD  - Institute of Population Health Sciences, Queen Mary's University, London, UK.
FAU - Ali, Afia
AU  - Ali A
AD  - UCL Division of Psychiatry and Camden Learning Disability Service, London, UK.
FAU - Hunter, Rachael
AU  - Hunter R
AD  - UCL Division of Psychiatry and Camden Learning Disability Service, London, UK.
FAU - Elahi, Farah
AU  - Elahi F
AD  - Camden and Islington Foundation NHS Trust, London, UK.
FAU - Chauhan, Umesh
AU  - Chauhan U
AD  - University of Central Lancashire, UK.
FAU - Rapaport, Penny
AU  - Rapaport P
AD  - UCL Division of Psychiatry and Camden Learning Disability Service, London, UK.
FAU - Marston, Louise
AU  - Marston L
AD  - UCL Division of Psychiatry and Camden Learning Disability Service, London, UK.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
DEP - 20220303
PL  - United States
TA  - Res Dev Disabil
JT  - Research in developmental disabilities
JID - 8709782
SB  - IM
MH  - Aggression
MH  - Caregivers
MH  - Checklist
MH  - Humans
MH  - *Intellectual Disability
MH  - *Minimal Clinically Important Difference
OTO - NOTNLM
OT  - Aggressive challenging behaviour
OT  - Clinical trials
OT  - Intellectual Disabilities
OT  - MCID
OT  - RCT
EDAT- 2022/03/07 06:00
MHDA- 2022/04/01 06:00
CRDT- 2022/03/06 20:30
PHST- 2021/10/04 00:00 [received]
PHST- 2022/02/09 00:00 [revised]
PHST- 2022/02/19 00:00 [accepted]
PHST- 2022/03/07 06:00 [pubmed]
PHST- 2022/04/01 06:00 [medline]
PHST- 2022/03/06 20:30 [entrez]
AID - S0891-4222(22)00032-4 [pii]
AID - 10.1016/j.ridd.2022.104202 [doi]
PST - ppublish
SO  - Res Dev Disabil. 2022 May;124:104202. doi: 10.1016/j.ridd.2022.104202. Epub 2022 
      Mar 3.