PMID- 35254722 OWN - NLM STAT- MEDLINE DCOM- 20230322 LR - 20230330 IS - 1934-1563 (Electronic) IS - 1934-1482 (Linking) VI - 15 IP - 3 DP - 2023 Mar TI - Ultrasound-guided percutaneous carpal tunnel release: A systematic review. PG - 363-379 LID - 10.1002/pmrj.12801 [doi] AB - OBJECTIVE: Carpal tunnel syndrome (CTS) is the most common peripheral entrapment mononeuropathy. The purpose of this systematic review is to evaluate the reported clinical effectiveness and safety of ultrasound-guided percutaneous carpal tunnel release (USCTR) for the treatment of CTS. LITERATURE SURVEY: PubMed, EMBASE, and ScienceDirect databases were queried from database inception to February 20, 2021, to identify clinical studies on USCTR. METHODOLOGY: Two reviewers independently completed title, abstract, and full-text screening, and they extracted data in duplicate for analysis. Procedure techniques, outcome measures, and complications were descriptively analyzed. SYNTHESIS: Eighty-seven studies were eligible for screening. Twenty studies (three randomized controlled trials, three prospective cohort studies, and 14 case series) met inclusion criteria, with a total of 1772 USCTR cases. The overall level of evidence was very low, with seven studies with at least moderate risk of bias. Thirteen studies exceeded the minimal clinically important difference (MCID) for the Boston Carpal Tunnel Questionnaire Symptom Severity Scale (BCTQ-SS) and Boston Carpal Tunnel Questionnaire Functional Status Scale (BCTQ-FS), and six studies exceeded the MCID for the Quick Disabilities of Arm, Shoulder & Hand (QDASH). Five studies reported statistically significant improvement in these functional outcome measures as early as the first week post-procedure. A major complication occurred in one patient who developed suspected compartment syndrome, and minor complications were reported in 24 patients. CONCLUSIONS: Based on very low level of evidence, early studies suggest that USCTR may be an effective treatment for CTS, with potential for short post-procedure recovery times. CI - (c) 2022 American Academy of Physical Medicine and Rehabilitation. FAU - Chou, Raymond C AU - Chou RC AUID- ORCID: 0000-0001-6436-5525 AD - Physical Medicine and Rehabilitation Division, Department of Orthopaedic Surgery, Stanford University, Redwood City, California, USA. FAU - Robinson, David M AU - Robinson DM AD - Sports Medicine Division, Department of Orthopedic Surgery, Mayo Clinic, Minneapolis, Minnesota, USA. FAU - Homer, Scott AU - Homer S AD - Department of Physical Medicine and Rehabilitation, Spaulding Rehabilitation Hospital/Harvard Medical School, Charlestown, Massachusetts, USA. AD - Department of Orthopaedic Surgery, Brigham and Women's Hospital/Harvard Medical School, Boston, Massachusetts, USA. LA - eng PT - Journal Article PT - Review PT - Systematic Review DEP - 20220516 PL - United States TA - PM R JT - PM & R : the journal of injury, function, and rehabilitation JID - 101491319 SB - IM MH - Humans MH - *Carpal Tunnel Syndrome/diagnostic imaging/surgery MH - Prospective Studies MH - Treatment Outcome MH - Outcome Assessment, Health Care MH - Ultrasonography, Interventional/methods MH - Surveys and Questionnaires EDAT- 2022/03/08 06:00 MHDA- 2023/03/23 06:00 CRDT- 2022/03/07 12:19 PHST- 2022/02/08 00:00 [revised] PHST- 2021/11/01 00:00 [received] PHST- 2022/02/25 00:00 [accepted] PHST- 2022/03/08 06:00 [pubmed] PHST- 2023/03/23 06:00 [medline] PHST- 2022/03/07 12:19 [entrez] AID - 10.1002/pmrj.12801 [doi] PST - ppublish SO - PM R. 2023 Mar;15(3):363-379. doi: 10.1002/pmrj.12801. Epub 2022 May 16.