PMID- 35259164
OWN - NLM
STAT- MEDLINE
DCOM- 20220427
LR  - 20240311
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 17
IP  - 3
DP  - 2022
TI  - Clinical improvement after surgery for degenerative cervical myelopathy; A 
      comparison of Patient-Reported Outcome Measures during 12-month follow-up.
PG  - e0264954
LID - 10.1371/journal.pone.0264954 [doi]
LID - e0264954
AB  - OBJECT: Although many patients report clinical improvement after surgery due to 
      degenerative cervical myelopathy, the aim of intervention is to stop progression 
      of spinal cord dysfunction. We wanted to provide estimates and assess achievement 
      rates of Minimal Clinically Important Difference (MCID) at 3- and 12-month 
      follow-up for Neck Disability Index (NDI), Numeric Rating Scale for arm pain 
      (NRS-AP) and neck pain (NRS-NP), Euro-Qol (EQ-5D-3L), and European Myelopathy 
      Score (EMS). METHODS: 614 degenerative cervical myelopathy patients undergoing 
      surgery responded to Patient-Reported Outcome Measures (PROMs) prior to, 3 and 12 
      months after surgery. External criterion was the Global Perceived Effect Scale 
      (1-7), defining MCID as "slightly better", "much better" and "completely 
      recovered". MCID estimates with highest sensitivity and specificity were 
      calculated by Receiver Operating Curves for change and percentage change scores 
      in the whole sample and in anterior and posterior procedural groups. RESULTS: The 
      NDI and NRS-NP percentage change scores were the most accurate PROMs with a MCID 
      of 16%. The change score for NDI and percentage change scores for NDI, NRS-AP and 
      NRS-NP were slightly higher in the anterior procedure group compared to the 
      posterior procedure group, while remaining PROM estimates were similar across 
      procedure type. The MCID achievement rates at 12-month follow-up ranged from 51% 
      in EMS to 62% in NRS-NP. CONCLUSION: The NDI and NRS-NP percentage change scores 
      were the most accurate PROMs to measure clinical improvement after surgery for 
      degenerative cervical myelopathy. We recommend using different cut-off estimates 
      for anterior and posterior approach procedures. A MCID achievement rate of 60% or 
      less must be interpreted in the perspective that the main goal of surgery for 
      degenerative cervical myelopathy is to prevent worsening of the condition.
FAU - Mjaset, Christer
AU  - Mjaset C
AUID- ORCID: 0000-0002-0210-1396
AD  - Faculty of Medicine, University of Oslo, Oslo, Norway.
AD  - Department of Neurosurgery, Oslo University Hospital, Oslo, Norway.
AD  - Department of Research and Innovation, Division of Clinical Neuroscience, Oslo 
      University Hospital, Oslo, Norway.
FAU - Zwart, John-Anker
AU  - Zwart JA
AD  - Faculty of Medicine, University of Oslo, Oslo, Norway.
AD  - Department of Research and Innovation, Division of Clinical Neuroscience, Oslo 
      University Hospital, Oslo, Norway.
FAU - Kolstad, Frode
AU  - Kolstad F
AD  - Department of Neurosurgery, Oslo University Hospital, Oslo, Norway.
FAU - Solberg, Tore
AU  - Solberg T
AD  - Institute of Clinical Medicine, The Arctic University of Norway, Tromso, Norway.
AD  - Department of Neurosurgery, The University Hospital of North Norway, Tromso, 
      Norway.
AD  - The Norwegian Registry for Spine Surgery, The University Hospital of North 
      Norway, Tromso, Norway.
FAU - Grotle, Margreth
AU  - Grotle M
AD  - Department of Research and Innovation, Division of Clinical Neuroscience, Oslo 
      University Hospital, Oslo, Norway.
AD  - Department of Physiotherapy, Faculty of Health Sciences, Oslo Metropolitan 
      University, Oslo, Norway.
LA  - eng
PT  - Journal Article
DEP - 20220308
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
EIN - PLoS One. 2024 Mar 11;19(3):e0300610. PMID: 38466707
MH  - Cervical Vertebrae/surgery
MH  - Follow-Up Studies
MH  - Humans
MH  - Neck Pain/surgery
MH  - Patient Reported Outcome Measures
MH  - *Spinal Cord Diseases/surgery
MH  - Treatment Outcome
PMC - PMC8903279
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/03/09 06:00
MHDA- 2022/04/28 06:00
PMCR- 2022/03/08
CRDT- 2022/03/08 17:11
PHST- 2021/08/06 00:00 [received]
PHST- 2022/02/18 00:00 [accepted]
PHST- 2022/03/08 17:11 [entrez]
PHST- 2022/03/09 06:00 [pubmed]
PHST- 2022/04/28 06:00 [medline]
PHST- 2022/03/08 00:00 [pmc-release]
AID - PONE-D-21-25531 [pii]
AID - 10.1371/journal.pone.0264954 [doi]
PST - epublish
SO  - PLoS One. 2022 Mar 8;17(3):e0264954. doi: 10.1371/journal.pone.0264954. 
      eCollection 2022.