PMID- 3526093 OWN - NLM STAT- MEDLINE DCOM- 19860916 LR - 20190725 IS - 0026-8925 (Print) IS - 0026-8925 (Linking) VI - 203 IP - 2 DP - 1986 May TI - Streptococcal pyrogenic exotoxin type A (scarlet fever toxin) is related to Staphylococcus aureus enterotoxin B. PG - 354-6 AB - The nucleotide sequence of the gene encoding group A streptococcal pyrogenic exotoxin type A (SPE A) was determined by the dideoxy chain termination method. The first 30 residues of the translation product represented a hydrophobic signal peptide. The mature protein was 220 amino acids in length and had a molecular weight of 25,805. It has significant protein sequence homology with Staphylococcus aureus enterotoxin B but not with other proteins in the Dayhoff library. FAU - Johnson, L P AU - Johnson LP FAU - L'Italien, J J AU - L'Italien JJ FAU - Schlievert, P M AU - Schlievert PM LA - eng SI - GENBANK/X03929 PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - Germany TA - Mol Gen Genet JT - Molecular & general genetics : MGG JID - 0125036 RN - 0 (Bacterial Proteins) RN - 0 (Enterotoxins) RN - 0 (Exotoxins) RN - 0 (Membrane Proteins) RN - 0 (SpeA protein, Streptococcus pyogenes) RN - 0 (erythrogenic toxin) RN - 39424-53-8 (enterotoxin B, staphylococcal) SB - IM MH - Amino Acid Sequence MH - *Bacterial Proteins MH - Enterotoxins/*genetics MH - Exotoxins/*genetics MH - *Genes MH - *Genes, Bacterial MH - *Membrane Proteins MH - Sequence Homology, Nucleic Acid MH - Staphylococcus aureus/*genetics MH - Streptococcus pyogenes/*genetics EDAT- 1986/05/01 00:00 MHDA- 1986/05/01 00:01 CRDT- 1986/05/01 00:00 PHST- 1986/05/01 00:00 [pubmed] PHST- 1986/05/01 00:01 [medline] PHST- 1986/05/01 00:00 [entrez] AID - 10.1007/BF00333979 [doi] PST - ppublish SO - Mol Gen Genet. 1986 May;203(2):354-6. doi: 10.1007/BF00333979.