PMID- 35262045 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220310 IS - 2667-7474 (Electronic) IS - 2667-7466 (Print) IS - 2667-7466 (Linking) VI - 59 IP - 4 DP - 2021 Dec TI - En Bloc Resection of Supraglottic Carcinomas with Transoral Laser Microsurgery. PG - 282-288 LID - 10.4274/tao.2021.2021-8-13 [doi] AB - OBJECTIVE: Complete en bloc supraglottic tumor excision with transoral laser microsurgery (TLM) can be achieved with good postoperative outcomes. We report surgical feasibility and the postsurgical outcomes of en bloc resection of supraglottic laryngeal squamous cell carcinomas (LSCC) with TLM. METHODS: Seventeen patients who underwent TLM for supraglottic laryngeal cancer were included in the study. Demographic and pathological data, clinic and follow-up outcomes of the patients were reviewed and analyzed. RESULTS: Type 1 TLM was performed in three patients, type 2a in one patient, type 3b in 12 patients, and type 4b in one patient. Negative surgical margins were achieved in all of the cases. Re-excision or any adjuvant treatment for positive resection margins was not required in any of the cases. Eight patients received adjuvant radiotherapy due to lymph node metastasis. Mean follow-up time was 33.8+/-15.7 months (range: 10-65 months). None of the patients had recurrence or distant metastasis. CONCLUSION: The transoral approach with the use of CO(2) laser and microscopy offers complete tumor excision for treating supraglottic LSCC. The three-dimensional structure of the supraglottis can be achieved with adequate exposure. En bloc resection is possible with safe margins. CI - (c)Copyright 2021 by Official Journal of the Turkish Society of Otorhinolaryngology and Head and Neck Surgery. FAU - Ozturk, Kerem AU - Ozturk K AUID- ORCID: 0000-0003-4608-6105 AD - Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey. FAU - Ozturk, Arin AU - Ozturk A AUID- ORCID: 0000-0002-3321-7033 AD - Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey. FAU - Turhal, Goksel AU - Turhal G AUID- ORCID: 0000-0003-0020-1921 AD - Department of Otorhinolaryngology, Ege University Faculty of Medicine, Izmir, Turkey. LA - eng PT - Journal Article DEP - 20220222 PL - Turkey TA - Turk Arch Otorhinolaryngol JT - Turkish archives of otorhinolaryngology JID - 101682806 PMC - PMC8864201 OTO - NOTNLM OT - Larynx carcinoma OT - partial laryngectomy OT - squamous cell carcinoma OT - supraglottic carcinoma OT - transoral laser microsurgery COIS- Conflict of Interest: No conflict of interest was declared by the authors. EDAT- 2022/03/10 06:00 MHDA- 2022/03/10 06:01 PMCR- 2021/12/01 CRDT- 2022/03/09 08:45 PHST- 2021/09/18 00:00 [received] PHST- 2021/11/11 00:00 [accepted] PHST- 2022/03/09 08:45 [entrez] PHST- 2022/03/10 06:00 [pubmed] PHST- 2022/03/10 06:01 [medline] PHST- 2021/12/01 00:00 [pmc-release] AID - 50796 [pii] AID - 10.4274/tao.2021.2021-8-13 [doi] PST - ppublish SO - Turk Arch Otorhinolaryngol. 2021 Dec;59(4):282-288. doi: 10.4274/tao.2021.2021-8-13. Epub 2022 Feb 22.