PMID- 35264128
OWN - NLM
STAT- MEDLINE
DCOM- 20220311
LR  - 20220319
IS  - 1471-2474 (Electronic)
IS  - 1471-2474 (Linking)
VI  - 23
IP  - 1
DP  - 2022 Mar 9
TI  - Quality of life assessment after total knee arthroplasty in patients with 
      Parkinson's disease.
PG  - 230
LID - 10.1186/s12891-022-05176-1 [doi]
LID - 230
AB  - BACKGROUND: The number of Parkinson's patients (PD) undergoing total knee 
      arthroplasty (TKA) is increasing. The purpose of the study was to characterize 
      quality of life (QOL) outcomes for patients with coexisting PD and knee 
      osteoarthritis (KOA) following TKA. METHODS: Patients with coexisting PD and KOA 
      undergoing TKA between June 2014 and June 2020 were included. These patients were 
      matched to controls with KOA alone by age, gender, basic social background 
      information and Knee society score (KSS). The primary measure was to assess the 
      QOL by the absolute changes in the EuroQOL5-Dimensions (EQ-5D), Pain and 
      Disability Questionnaire (PDQ), and Patient Health Questionnaire-9(PHQ-9) at the 
      last follow-up (LFU). Secondary measures were changes in QOL that exceeded the 
      minimum clinically important difference value (MCID). Data on the health status 
      and QOL of all patients were collected. Simple and multivariate regression 
      analysis was used to evaluate the impact of PD on their QOL. RESULTS: Twelve KOA 
      patients with PD were compared with 48 controls. Control patients experienced QOL 
      improvement across all three measures:EQ-5D index (0.545-0.717, P < 0.01), PDQ 
      (81.1-52.3, P < 0.01) and PHQ-9(8.22-5.91, P < 0.01) were significantly improved 
      at the LFU; while in patients with PD, only PDQ (91.0-81.4, P = 0.03) slightly 
      improved. There were significant differences in the improvement of QOL between PD 
      patients and the control group through EQ-5D (0.531 vs.0.717, P < 0.01) and PDQ 
      (81.4vs.52.3, P < 0.01) at the LFU. CONCLUSION: TKA has no benefit of QOL beyond 
      a slight improvement in pain-related disability in the KOA patients with PD.
CI  - (c) 2022. The Author(s).
FAU - Zong, Yaqi
AU  - Zong Y
AD  - Department of Orthopedics, Bao Di Clinical College of Tianjin Medical University, 
      Bao Di Hospital, 8 Guangchuan Road, Baodi District, Tianjin, 301800, Tianjin, 
      China.
FAU - Hao, Congqiang
AU  - Hao C
AD  - Department of Orthopedics, Bao Di Clinical College of Tianjin Medical University, 
      Bao Di Hospital, 8 Guangchuan Road, Baodi District, Tianjin, 301800, Tianjin, 
      China.
FAU - Zhang, Yingjian
AU  - Zhang Y
AD  - Department of Orthopedics, Bao Di Clinical College of Tianjin Medical University, 
      Bao Di Hospital, 8 Guangchuan Road, Baodi District, Tianjin, 301800, Tianjin, 
      China.
FAU - Wu, Shuwen
AU  - Wu S
AD  - Department of Orthopedics, Bao Di Clinical College of Tianjin Medical University, 
      Bao Di Hospital, 8 Guangchuan Road, Baodi District, Tianjin, 301800, Tianjin, 
      China. 819069049@qq.com.cn.
LA  - eng
PT  - Journal Article
DEP - 20220309
PL  - England
TA  - BMC Musculoskelet Disord
JT  - BMC musculoskeletal disorders
JID - 100968565
SB  - IM
MH  - *Arthroplasty, Replacement, Knee/adverse effects
MH  - Humans
MH  - *Osteoarthritis, Knee/complications/diagnosis/surgery
MH  - *Parkinson Disease/complications/diagnosis/surgery
MH  - Quality of Life
MH  - Treatment Outcome
PMC - PMC8908622
OTO - NOTNLM
OT  - Knee Osteoarthritis
OT  - Parkinson's Disease
OT  - The Quality of Life
OT  - Total Knee Arthroplasty
COIS- The authors declare that they have no competing interests.
EDAT- 2022/03/11 06:00
MHDA- 2022/03/12 06:00
PMCR- 2022/03/09
CRDT- 2022/03/10 05:33
PHST- 2021/12/08 00:00 [received]
PHST- 2022/03/02 00:00 [accepted]
PHST- 2022/03/10 05:33 [entrez]
PHST- 2022/03/11 06:00 [pubmed]
PHST- 2022/03/12 06:00 [medline]
PHST- 2022/03/09 00:00 [pmc-release]
AID - 10.1186/s12891-022-05176-1 [pii]
AID - 5176 [pii]
AID - 10.1186/s12891-022-05176-1 [doi]
PST - epublish
SO  - BMC Musculoskelet Disord. 2022 Mar 9;23(1):230. doi: 10.1186/s12891-022-05176-1.