PMID- 35267842 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230308 IS - 2073-4360 (Electronic) IS - 2073-4360 (Linking) VI - 14 IP - 5 DP - 2022 Mar 3 TI - A Multi-Attribute Decision-Making Model for the Selection of Polymer-Based Biomaterial for Orthopedic Industrial Applications. LID - 10.3390/polym14051020 [doi] LID - 1020 AB - The potential of quantifying the variations in IR active bands was explored while using the chemometric analysis of FTIR spectra for selecting orthopedic biomaterial of industrial scale i.e., ultra-high molecular weight PE (UHMWPE). The nano composites UHMWPE with multi-walled carbon nano-tubes (MWCNTs) and Mg-silicate were prepared and irradiated with 25 kGy and 50 kGy of gamma dose. Principal component analysis (PCA) revealed that first three principal components (PCs) are responsible for explaining the >99% of variance in FTIR data of UHMWPE on addition of fillers and/or irradiation. The factor loadings plots revealed that PC-1 was responsible for explaining the variance in polyethylene characteristics bands and the IR active region induced by fillers i.e., 440 cm-1, 456 cm-1, from 900-1200 cm-1, 1210 cm-1, 1596 cm-1, PC-2 was responsible for explaining the variance in spectra due to radiation-induced oxidation and cross linking, while the PC-3 is responsible for explaining the variance induced because of IR active bands of MWCNTs. Hierarchy cluster analysis (HCA) was employed to classify the samples into four clusters with respect to similarity in their IR active bands which is further confirmed by PCA. According to multi attribute analysis with PCA and HCA, 65 kGy irradiated sample is optimum choice from the existing alternatives in the group of irradiated pristine UHMWPE, UHMWPE/Mg-silicate irradiated with 25 kGy of gamma dose was the optimum choice for UHWMPE/Mg-silicate nano composites, and UHMWPE/gammaMWCNTs composites containing 1.0% dof gamma MWCNTs for UHMWPE/MWCNTs nanocomposites, respectively. The results show the effectiveness of quantifying the variance for decision as far as optimization of biomaterials in orthopedic industrial applications is concerned. FAU - Rizwan, Ali AU - Rizwan A AUID- ORCID: 0000-0002-2348-8577 AD - Department of Industrial Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia. FAU - Abualsauod, Emad H AU - Abualsauod EH AUID- ORCID: 0000-0002-1717-1119 AD - Department of Industrial Engineering, College of Engineering, Taibah University, Medina 41411, Saudi Arabia. FAU - Othman, Asem Majed AU - Othman AM AD - Department of Industrial and Systems Engineering, College of Engineering, University of Jeddah, Jeddah 21959, Saudi Arabia. FAU - Serbaya, Suhail H AU - Serbaya SH AUID- ORCID: 0000-0003-0541-0511 AD - Department of Industrial Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia. FAU - Shahzad, Muhammad Atif AU - Shahzad MA AUID- ORCID: 0000-0003-2058-3648 AD - Department of Industrial Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia. FAU - Hameed, Abdul Zubar AU - Hameed AZ AD - Department of Industrial Engineering, Faculty of Engineering, King Abdulaziz University, Jeddah 21589, Saudi Arabia. LA - eng GR - G: 706-135-1443/Deanship of Scientific Research (DSR), King Abdulaziz University, Jeddah,/ PT - Journal Article DEP - 20220303 PL - Switzerland TA - Polymers (Basel) JT - Polymers JID - 101545357 PMC - PMC8912859 OTO - NOTNLM OT - FTIR spectroscopy OT - MWCNTs OT - PCA OT - UHMWPE OT - chemo metric analysis OT - industrial applications OT - optimization OT - scree plot COIS- The authors declare no conflict of interest. EDAT- 2022/03/11 06:00 MHDA- 2022/03/11 06:01 PMCR- 2022/03/03 CRDT- 2022/03/10 15:26 PHST- 2022/02/09 00:00 [received] PHST- 2022/02/27 00:00 [revised] PHST- 2022/03/01 00:00 [accepted] PHST- 2022/03/10 15:26 [entrez] PHST- 2022/03/11 06:00 [pubmed] PHST- 2022/03/11 06:01 [medline] PHST- 2022/03/03 00:00 [pmc-release] AID - polym14051020 [pii] AID - polymers-14-01020 [pii] AID - 10.3390/polym14051020 [doi] PST - epublish SO - Polymers (Basel). 2022 Mar 3;14(5):1020. doi: 10.3390/polym14051020.