PMID- 35277161
OWN - NLM
STAT- MEDLINE
DCOM- 20220315
LR  - 20220317
IS  - 1471-2474 (Electronic)
IS  - 1471-2474 (Linking)
VI  - 23
IP  - 1
DP  - 2022 Mar 11
TI  - Clinical outcomes one year after a digital musculoskeletal (MSK) program: an 
      observational, longitudinal study with nonparticipant comparison group.
PG  - 237
LID - 10.1186/s12891-022-05188-x [doi]
LID - 237
AB  - BACKGROUND: The evidence base for the impact of digital health on musculoskeletal 
      (MSK) outcomes is growing, but it is unclear how much digital MSK programs 
      address pain and function in the intermediate and long term. METHODS: This 
      observational study of digital MSK program participants versus nonparticipants 
      (n = 2570) examined pain, function, depression, and anxiety at 3, 6, and 
      12 months, and health care use at 12 months. The intervention group engaged in a 
      digital MSK program that included exercise, education, and coaching for at least 
      3 months. The nonparticipant group registered, but never started the program. We 
      collected data in app or by emailed survey at 3, 6, and 12 months after 
      registering for the program. We conducted descriptive analyses and unadjusted and 
      adjusted regression modeling. RESULTS: The odds ratio of achieving a minimally 
      clinically important difference (MCID) in pain improvement for the intervention 
      versus the nonparticipant group was 1.97 (95% CI: 1.28, 3.02; p = .002) at 
      3 months, 1.44 (95% CI: 0.91, 2.25; p = .11) at 6 months, and 2.06 (95% CI: 1.38, 
      3.08; p = .004) at 12 months in adjusted models. The odds ratio of achieving a 
      MCID in functional improvement for the intervention versus the nonparticipant 
      group was 1.56 (95% CI: 1.03, 2.38; p = .01) at 3 months, 1.55 (95% CI: 1.02, 
      2.37; p = .04) at 6 months, and 1.35 (95% CI: 0.89, 2.06, p = 0.16) at 12 months 
      in adjusted models. For those with moderate to severe depression or anxiety at 
      baseline, we observed statistically significant lower odds of moderate to severe 
      depression or anxiety at 3 months, 6 months, and 12 months for the intervention 
      versus the nonparticipant group in adjusted models (p < .05). At 12 months, the 
      percentage with invasive, imaging, and conservative services was higher for the 
      nonparticipant versus intervention group by 5.7, 8.1, and 16.7 percentage points, 
      respectively (p < 0.05). CONCLUSIONS: A digital MSK program may offer 
      participants sustained improvement in pain, depression, and anxiety with 
      concomitant decreases in health care use.
CI  - (c) 2022. The Author(s).
FAU - Wang, Grace
AU  - Wang G
AUID- ORCID: 0000-0002-1392-1218
AD  - Hinge Health, Inc., 455 Market Street, Suite 700, CA, 94105, San Francisco, USA. 
      grace.wang@hingehealth.com.
FAU - Yang, Manshu
AU  - Yang M
AD  - Department of Psychology, University of Rhode Island, Chafee Hall 406, 142 Flagg 
      Road, Kingston, RI, 02881, USA.
FAU - Hong, Mindy
AU  - Hong M
AD  - Hinge Health, Inc., 455 Market Street, Suite 700, CA, 94105, San Francisco, USA.
FAU - Krauss, Jeffrey
AU  - Krauss J
AD  - Hinge Health, Inc., 455 Market Street, Suite 700, CA, 94105, San Francisco, USA.
FAU - Bailey, Jeannie F
AU  - Bailey JF
AD  - Orthopaedic Surgery, University of California, San Francisco, 95 Kirkham St., San 
      Francisco, CA, 94122, USA.
LA  - eng
PT  - Journal Article
PT  - Observational Study
DEP - 20220311
PL  - England
TA  - BMC Musculoskelet Disord
JT  - BMC musculoskeletal disorders
JID - 100968565
SB  - IM
MH  - Anxiety/diagnosis/epidemiology/therapy
MH  - *Anxiety Disorders
MH  - Humans
MH  - Longitudinal Studies
MH  - *Pain
MH  - Surveys and Questionnaires
PMC - PMC8914456
OTO - NOTNLM
OT  - Anxiety
OT  - Depression
OT  - Function
OT  - Musculoskeletal pain
OT  - Telemedicine
COIS- Hinge Health, Inc. employees and manuscript authors GW, MH, and JK designed the 
      study, interpreted results, and wrote the manuscript. Hinge Health, Inc. 
      employees GW and MH analyzed data. GW, MH, and JK have equity interest in Hinge 
      Health, Inc.
EDAT- 2022/03/13 06:00
MHDA- 2022/03/16 06:00
PMCR- 2022/03/11
CRDT- 2022/03/12 05:21
PHST- 2021/10/05 00:00 [received]
PHST- 2022/03/04 00:00 [accepted]
PHST- 2022/03/12 05:21 [entrez]
PHST- 2022/03/13 06:00 [pubmed]
PHST- 2022/03/16 06:00 [medline]
PHST- 2022/03/11 00:00 [pmc-release]
AID - 10.1186/s12891-022-05188-x [pii]
AID - 5188 [pii]
AID - 10.1186/s12891-022-05188-x [doi]
PST - epublish
SO  - BMC Musculoskelet Disord. 2022 Mar 11;23(1):237. doi: 10.1186/s12891-022-05188-x.