PMID- 35277363 OWN - NLM STAT- MEDLINE DCOM- 20220426 LR - 20220613 IS - 1871-403X (Print) IS - 1871-403X (Linking) VI - 16 IP - 2 DP - 2022 Mar-Apr TI - Explorations on risk profiles for overweight and obesity in 9501 preschool-aged children. PG - 106-114 LID - S1871-403X(22)00019-9 [pii] LID - 10.1016/j.orcp.2022.02.007 [doi] AB - BACKGROUND: Childhood obesity places a major burden on global public health. We aimed to identify and characterize potential factors, both individually and jointly, in association with overweight and obesity in Chinese preschool-aged children. METHODS: We cross-sectionally recruited 9501 preschool-aged children from 30 kindergartens in Beijing and Tangshan. Overweight and obesity are defined according to the World Health Organization (WHO), International Obesity Task Force (IOTF), and China criteria. RESULTS: After multivariable adjustment, eating speed, sleep duration, birthweight, and paternal body mass index (BMI) were consistently and significantly associated with childhood overweight and obesity under three growth criteria at a significance level of 5%. Additional fast food intake frequency, maternal BMI, gestational weight gain (GWG) and maternal pre-pregnancy BMI were significant factors for overweight (WHO criteria) and obesity (both IOTF and China criteria). Importantly, there were significant interactions between parental obesity and eating speed for childhood obesity. Finally, for practical reasons, risk nomogram models were constructed for childhood overweight and obesity based on significant factors under each criterion, with good prediction accuracy. CONCLUSION: Our findings indicated a synergistic association of lifestyle, fetal and neonatal, and family-related factors with the risk of experiencing overweight and obesity among preschool-aged children. CI - Copyright (c) 2022. Published by Elsevier Ltd. FAU - Wang, Qiong AU - Wang Q AD - Graduate School, Beijing University of Chinese Medicine, Beijing, China; Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China. FAU - Yang, Min AU - Yang M AD - Graduate School, Beijing University of Chinese Medicine, Beijing, China; Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China. FAU - Deng, Xiangling AU - Deng X AD - Graduate School, Beijing University of Chinese Medicine, Beijing, China; Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China. FAU - Wang, Shunan AU - Wang S AD - Graduate School, Beijing University of Chinese Medicine, Beijing, China; Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China. FAU - Zhou, Bo AU - Zhou B AD - Graduate School, Beijing University of Chinese Medicine, Beijing, China; Department of Pediatrics, China-Japan Friendship Hospital, Beijing, China. FAU - Li, Xiumei AU - Li X AD - Department of Pediatrics, Changping District Maternal and Child Health Care Hospital, Beijing, China. FAU - Shi, Jinfeng AU - Shi J AD - Department of Pediatrics, Tangshan Maternal and Child Health Care Hospital, Hebei, China. FAU - Zhang, Zhixin AU - Zhang Z AD - International Medical Services, China-Japan Friendship Hospital, Beijing, China. Electronic address: zhangzhixin032@163.com. FAU - Niu, Wenquan AU - Niu W AD - Institute of Clinical Medical Sciences, China-Japan Friendship Hospital, Beijing, China. Electronic address: niuwenquan_shcn@163.com. LA - eng PT - Journal Article DEP - 20220309 PL - Netherlands TA - Obes Res Clin Pract JT - Obesity research & clinical practice JID - 101303911 SB - IM MH - Body Mass Index MH - Child MH - Child, Preschool MH - China/epidemiology MH - Female MH - *Gestational Weight Gain MH - Humans MH - Infant, Newborn MH - Overweight/epidemiology/etiology MH - *Pediatric Obesity/epidemiology/etiology MH - Pregnancy MH - Risk Factors OTO - NOTNLM OT - Childhood overweight and obesity OT - Interaction OT - Nomogram OT - Preschool-aged children OT - Risk profile EDAT- 2022/03/13 06:00 MHDA- 2022/04/27 06:00 CRDT- 2022/03/12 05:24 PHST- 2021/06/24 00:00 [received] PHST- 2022/02/02 00:00 [revised] PHST- 2022/02/20 00:00 [accepted] PHST- 2022/03/13 06:00 [pubmed] PHST- 2022/04/27 06:00 [medline] PHST- 2022/03/12 05:24 [entrez] AID - S1871-403X(22)00019-9 [pii] AID - 10.1016/j.orcp.2022.02.007 [doi] PST - ppublish SO - Obes Res Clin Pract. 2022 Mar-Apr;16(2):106-114. doi: 10.1016/j.orcp.2022.02.007. Epub 2022 Mar 9.