PMID- 35280885
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220315
IS  - 2296-858X (Print)
IS  - 2296-858X (Electronic)
IS  - 2296-858X (Linking)
VI  - 9
DP  - 2022
TI  - Allergic Bronchopulmonary Mycosis Caused by Mucor Overlapping With Invasive 
      Pulmonary Mucormycosis: A Case Report.
PG  - 831213
LID - 10.3389/fmed.2022.831213 [doi]
LID - 831213
AB  - Mucormycosis is a rare and invasive fungal infection with high mortality. Cases 
      of invasive pulmonary mucormycosis that involve allergic reactions such as 
      allergic bronchopulmonary mycosis are rarely reported. Herein, we describe a case 
      of invasive pulmonary mucormycosis overlapping with allergic diseases in a 
      patient who presented with eosinophilia and high total plasma immunoglobulin E 
      (IgE). The patient was successfully treated with systemic corticosteroids 
      (initial dose of prednisolone approximately 0.5 mg/kg per day, total duration 
      less than 3 months) combined with posaconazole antifungal therapy. The treatment 
      resulted in recovery of peripheral-blood eosinophil count and total plasma IgE, 
      and significant reduction in lung lesions. A subsequent lobectomy was performed. 
      The findings in this case indicate that systemic corticosteroid therapy may 
      contribute to the treatment of pulmonary mucormycosis combined with allergic 
      factors.
CI  - Copyright (c) 2022 Zhang, Jin, Zhan, Shen, Yao, Gao, Yang, Zhou and Zhou.
FAU - Zhang, Ruhui
AU  - Zhang R
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
FAU - Jin, Ge
AU  - Jin G
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
FAU - Zhan, Yasheng
AU  - Zhan Y
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
FAU - Shen, Lisha
AU  - Shen L
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
FAU - Yao, Yake
AU  - Yao Y
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
FAU - Gao, Qiqi
AU  - Gao Q
AD  - Department of Pathology, The First Affiliated Hospital, Zhejiang University 
      School of Medicine, Hangzhou, China.
FAU - Yang, Qing
AU  - Yang Q
AD  - State Key Lab for Diagnostic and Treatment of Infectious Diseases, First 
      Affiliated Hospital, Zhejiang University, Hangzhou, China.
FAU - Zhou, Jianying
AU  - Zhou J
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
FAU - Zhou, Hua
AU  - Zhou H
AD  - Department of Respiratory and Critical Care Medicine, The First Affiliated 
      Hospital, Zhejiang University School of Medicine, Hangzhou, China.
LA  - eng
PT  - Case Reports
DEP - 20220224
PL  - Switzerland
TA  - Front Med (Lausanne)
JT  - Frontiers in medicine
JID - 101648047
PMC - PMC8907707
OTO - NOTNLM
OT  - IgE
OT  - allergic bronchopulmonary mycosis
OT  - glucocorticoid
OT  - invasive pulmonary mucormycosis
OT  - mucor
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/03/15 06:00
MHDA- 2022/03/15 06:01
PMCR- 2022/02/24
CRDT- 2022/03/14 05:15
PHST- 2021/12/08 00:00 [received]
PHST- 2022/01/12 00:00 [accepted]
PHST- 2022/03/14 05:15 [entrez]
PHST- 2022/03/15 06:00 [pubmed]
PHST- 2022/03/15 06:01 [medline]
PHST- 2022/02/24 00:00 [pmc-release]
AID - 10.3389/fmed.2022.831213 [doi]
PST - epublish
SO  - Front Med (Lausanne). 2022 Feb 24;9:831213. doi: 10.3389/fmed.2022.831213. 
      eCollection 2022.